anti-Ubiquitin Specific Peptidase 14 (USP14) Antikörper

USP14 encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. Zusätzlich bieten wir Ihnen USP14 Proteine (15) und USP14 Kits (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
USP14 9097 P54578
USP14 59025 Q9JMA1
USP14 291796  
Direkt bei antikoerper-online bestellen
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Online bestellen
  • orders@antikoerper-online.de

Top anti-USP14 Antikörper auf antikoerper-online.de

Showing 10 out of 86 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Maus Unkonjugiert IF, WB Immunofluorescence of monoclonal antibody to USP14 on HeLa cell (antibody concentration 20 µg/mL). USP14 monoclonal antibody (M04), clone 6D6 Western Blot analysis of USP14 expression in HeLa. 0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$450.00
Details
Human Maus Unkonjugiert WB USP14 monoclonal antibody (M08), clone 1F8. Western Blot analysis of USP14 expression in Hela NE. 0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$450.00
Details
Human Maus Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$537.17
Details
Human Kaninchen Unkonjugiert IHC (p), WB The anti-USP14 Pab (ABIN388902) is used in Western blot to detect USP14 in USP14-transfected HeLa cell lysates. Transfection data is kindly provided by Dr. B. Pierrat from the Novartis Institute for Biomedical Research (Basel, Switzerland). Western blot analysis of anti-USP14 Pab (ABIN388902) in A2058 cell line lysates (35 µg/lane). USP14 (arrow) was detected using the purified polyclonal antibody. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert WB WB Image Sample (30 ug of whole cell lysate) A: A431 , 10% SDS PAGE antibody diluted at 1:1000 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
$358.60
Details
Human Kaninchen Unkonjugiert WB USP14 Antibody (C-term) (ABIN1881985) western blot analysis in A2058 cell line lysates (35 µg/lane). This demonstrates the USP14 antibody detected the USP14 protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Maus Unkonjugiert IF, ELISA, WB USP14 monoclonal antibody (M04), clone 6D6 Western Blot analysis of USP14 expression in HeLa . Immunofluorescence of monoclonal antibody to USP14 on HeLa cell. [antibody concentration 20 ug/ml] 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Maus Unkonjugiert ELISA, WB USP14 monoclonal antibody (M08), clone 1F8. Western Blot analysis of USP14 expression in Hela S3 NE . Detection limit for recombinant GST tagged USP14 is approximately 1ng/ml as a capture antibody. 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
Details
Human Maus Unkonjugiert ELISA, WB USP14 polyclonal antibody (A01), Lot # 060707JCS1 Western Blot analysis of USP14 expression in Jurkat . USP14 polyclonal antibody (A01), Lot # 060707JCS1. Western Blot analysis of USP14 expression in NIH/3T3. 50 μL Anmelden zum Anzeigen 11 bis 12 Tage
$305.71
Details

USP14 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Human ,
, ,
,
, , , , ,
Mouse (Murine) ,
,
,
Rat (Rattus)
,
,

Am meisten referenzierte anti-USP14 Antikörper

  1. Human Polyclonal USP14 Primary Antibody für WB - ABIN1881985 : Chen, Qin, Li, Walters, Wilson, Mei, Wilson: The proteasome-associated deubiquitinating enzyme Usp14 is essential for the maintenance of synaptic ubiquitin levels and the development of neuromuscular junctions. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2009 (PubMed)
    Show all 6 Pubmed References

  2. Human Monoclonal USP14 Primary Antibody für WB - ABIN1882288 : Reuter, Medhurst, Waisfisz, Zhi, Herterich, Hoehn, Gross, Joenje, Hoatlin, Mathew, Huber: Yeast two-hybrid screens imply involvement of Fanconi anemia proteins in transcription regulation, cell signaling, oxidative metabolism, and cellular transport. in Experimental cell research 2003 (PubMed)
    Show all 3 Pubmed References

  3. Human Monoclonal USP14 Primary Antibody für IF, ELISA - ABIN563939 : Hyrskyluoto, Bruelle, Lundh, Do, Kivinen, Rappou, Reijonen, Waltimo, Petersén, Lindholm, Korhonen: Ubiquitin-specific protease-14 reduces cellular aggregates and protects against mutant huntingtin-induced cell degeneration: involvement of the proteasome and ER stress-activated kinase IRE1?. in Human molecular genetics 2014 (PubMed)

  4. Human Polyclonal USP14 Primary Antibody für IHC (p), WB - ABIN388902 : Mines, Goodwin, Limbird, Cui, Fan: Deubiquitination of CXCR4 by USP14 is critical for both CXCL12-induced CXCR4 degradation and chemotaxis but not ERK ativation. in The Journal of biological chemistry 2009 (PubMed)

Weitere Antikörper gegen USP14 Interaktionspartner

Human Ubiquitin Specific Peptidase 14 (USP14) Interaktionspartner

  1. Study detected elevated USP14 expression at both mRNA and protein levels, and was significantly associated with distant metastasis.

  2. These findings suggested that USP14 induces NF-kappaB activity and ERK1/2 phosphorylation triggered by microbial infection.

  3. Ubiquitin-specific protease 14 regulates cell proliferation and apoptosis in oral squamous cell carcinoma

  4. our report demonstrates significant value in targeting USP14/UCHL5 (zeige UCHL5 Antikörper) with VLX1570 in drug-resistant Waldenstrom macroglobulinemia (WM) and carries a high potential for clinical translation

  5. USP14 promotes prostate cancer progression.

  6. without a ubiquitinated substrate present, Usp14 suppresses multiple proteasomal activities, especially basal ATP consumption and degradation of non-ubiquitinated proteins. These allosteric effects thus reduce ATP hydrolysis by inactive proteasomes and nonspecific proteolysis and enhance proteasomal specificity for ubiquitinated proteins.

  7. USP14 regulates autophagy by negatively controlling K63 ubiquitination of Beclin 1 (zeige BECN1 Antikörper)

  8. USP14 plays an important role in the progression and metastasis of esophageal squamous cell carcinoma.

  9. USP14 participates in CAM-DR of MM through acting as a bridge between Bcl-xl (zeige BCL2L1 Antikörper) apoptotic pathway and Wnt (zeige WNT2 Antikörper)-signaling pathways and may be represented as a good candidate for pursuing clinical trials in MM.

  10. Results show that USP14 mRNA is overexpressed in hepatocellular carcinoma (HCC (zeige FAM126A Antikörper)) tissues and inversely correlates with miR (zeige MLXIP Antikörper)-4782-3p level which binds to USP14 3'UTR (zeige UTS2R Antikörper) to regulate its expression.

Mouse (Murine) Ubiquitin Specific Peptidase 14 (USP14) Interaktionspartner

  1. analysis of the molecular mechanisms through which CBP stability is regulated by FBXL19 and USP14, which results in the modulation of chromatin remodeling and the expression of cytokine-encoding genes

  2. These findings suggested that USP14 induces NF-kappaB activity and ERK1/2 phosphorylation triggered by microbial infection.

  3. without a ubiquitinated substrate present, Usp14 suppresses multiple proteasomal activities, especially basal ATP consumption and degradation of non-ubiquitinated proteins. These allosteric effects thus reduce ATP hydrolysis by inactive proteasomes and nonspecific proteolysis and enhance proteasomal specificity for ubiquitinated proteins.

  4. USP14's catalytic activity is required for nervous system structure and function and has an ongoing role in NMJ synaptic transmission. USP14 regulation of the ubiquitination status of protein kinases, coordinates NMJ intracellular signaling pathways.

  5. Overexpression of the Usp14 reduces cellular aggregates in mutant Htt-expressing cells mainly via the ubiquitin proteasome system.

  6. USP14 modulates hippocampal short-term plasticity and vesicle number independent of its deubiquitinating activity.

  7. Differences in genetic background were shown to affect ubiquitin expression and dramatically alter the phenotypes caused by USP14 deficiency.

  8. Data indicate that increased levels of phosphorylated tau correlated with the onset of axonal varicosities in the ubiquitin-specific protease 14 (Usp14)-deficient mice.

  9. miR-124 promotes neuronal survival under ischemic conditions via Usp14-dependent REST degradation.

  10. overexpression of HA-USP14 increased TNFalpha (zeige TNF Antikörper)

USP14 Antigen-Profil

Protein Überblick

This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. Mice with a mutation that results in reduced expression of the ortholog of this protein are retarded for growth, develop severe tremors by 2 to 3 weeks of age followed by hindlimb paralysis and death by 6 to 10 weeks of age. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Genbezeichner und Symbole assoziert mit USP14

  • ubiquitin specific peptidase 14 (USP14) Antikörper
  • peptidase C19 family protein (usp14) Antikörper
  • ubiquitin specific peptidase 14 (Usp14) Antikörper
  • ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) (usp14) Antikörper
  • ubiquitin specific protease 14 (Bm1_28765) Antikörper
  • ubiquitin specific peptidase 14 S homeolog (usp14.S) Antikörper
  • ubiquitin specific peptidase 14 (usp14) Antikörper
  • universal stress protein (RR_RS06480) Antikörper
  • Ubiquitin carboxyl-terminal hydrolase 14 (usp-14) Antikörper
  • 2610005K12Rik Antikörper
  • 2610037B11Rik Antikörper
  • AW107924 Antikörper
  • ax Antikörper
  • C78769 Antikörper
  • DDBDRAFT_0202821 Antikörper
  • DDBDRAFT_0237695 Antikörper
  • DDB_0202821 Antikörper
  • DDB_0237695 Antikörper
  • MGC69343 Antikörper
  • MGC81945 Antikörper
  • tgt Antikörper
  • USP14 Antikörper
  • wu:fk63d09 Antikörper
  • zgc:55949 Antikörper

Bezeichner auf Proteinebene für USP14

deubiquitinating enzyme 14 , tRNA-guanine transglycosylase, 60-kD subunit , ubiquitin carboxyl-terminal hydrolase 14 , ubiquitin specific protease 14 (tRNA-guanine transglycosylase) , ubiquitin thioesterase 14 , ubiquitin thiolesterase 14 , ubiquitin-specific processing protease 14 , ubiquitin-specific-processing protease 14 , ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) , ubiquitin domain-containing protein , ataxia , dUB-type TGT for deubiquitinating enzyme , ubiquitin specific protease 14 , universal stress protein , queuine tRNA-ribosyltransferase , ubiquitin carboxyl-terminal hydrolase 14-like

GENE ID SPEZIES
9097 Homo sapiens
100090009 Ornithorhynchus anatinus
8617881 Dictyostelium discoideum AX4
59025 Mus musculus
291796 Rattus norvegicus
335736 Danio rerio
455325 Pan troglodytes
505106 Bos taurus
6100653 Brugia malayi
421063 Gallus gallus
447733 Xenopus laevis
448110 Xenopus (Silurana) tropicalis
480182 Canis lupus familiaris
698087 Macaca mulatta
3130489 Haloarcula marismortui ATCC 43049
100009078 Oryctolagus cuniculus
100013535 Monodelphis domestica
100394297 Callithrix jacchus
100473541 Ailuropoda melanoleuca
100586916 Nomascus leucogenys
175105 Caenorhabditis elegans
Ausgewählte Anbieter für anti-USP14 (USP14) Antikörper
Haben Sie etwas anderes gesucht?