anti-Ubiquitin Specific Peptidase 11 (USP11) Antikörper

Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. Zusätzlich bieten wir Ihnen USP11 Proteine (2) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
USP11 8237 P51784
USP11 236733 Q99K46
USP11 408217  
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Top anti-USP11 Antikörper auf antikoerper-online.de

Showing 10 out of 101 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Human Ziege Unkonjugiert ELISA, WB ABIN185009 staining (1 ug/ml) of Jurkat lysate (RIPA buffer, 30 ug total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. 100 μg 6 bis 7 Tage
$429.84
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of USP11 expression in Jurkat (A), SP2/0 (B), H9C2 (C) whole cell lysates. 200 μL 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL 6 bis 8 Tage
$484.00
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Human Kaninchen Unkonjugiert ELISA, WB 100 μL Verfügbar
$363.46
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Human Ziege Unkonjugiert ELISA, WB 100 μg 11 bis 14 Tage
$610.50
Details
Human Kaninchen Unkonjugiert ELISA, ICC, IF, WB Western blot analysis of extracts from 293 cells, using USP11 antibody. ABIN6275650 staining  293 cells by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25¡ãC. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37¡ãC. An  Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody(Cat.# S0006), diluted at 1/600, was used as secondary antibod 100 μL 11 bis 12 Tage
$390.77
Details
Human Ziege Unkonjugiert WB   0.1 mg 4 bis 8 Tage
$462.00
Details
Human Kaninchen Unkonjugiert ICC, IF, WB ICC/IF Image Confocal immunofluorescence analysis (Olympus FV10i) of paraformaldehyde-fixed HeLa, using USP11, antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with  (Red) at 1:2000. WB Image Sample(30 μg of whole cell lysate) A:HeLa S3, 7.5% SDS PAGE antibody diluted at 1:1000 100 μL 3 bis 4 Tage
$466.18
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of anti-USP11 Pab in Jurkat cell line lysates (35ug/lane). Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma; HC = hepatocarcinoma. 400 μL 2 bis 3 Tage
$515.63
Details
Human Maus Unkonjugiert FACS, WB 100 μL 11 bis 13 Tage
$366.77
Details

Am meisten referenzierte anti-USP11 Antikörper

  1. Human Polyclonal USP11 Primary Antibody für IHC (p), ELISA - ABIN545117 : Swanson, Freund, Ploder, McInnes, Valle: A ubiquitin C-terminal hydrolase gene on the proximal short arm of the X chromosome: implications for X-linked retinal disorders. in Human molecular genetics 1996 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal USP11 Primary Antibody für ELISA, WB - ABIN547089 : Ideguchi, Ueda, Tanaka, Yang, Tsuji, Ohno, Hagiwara, Aoki, Ishigatsubo: Structural and functional characterization of the USP11 deubiquitinating enzyme, which interacts with the RanGTP-associated protein RanBPM. in The Biochemical journal 2002 (PubMed)

Weitere Antikörper gegen USP11 Interaktionspartner

Human Ubiquitin Specific Peptidase 11 (USP11) Interaktionspartner

  1. USP11 is involved in chromatin condensation, genomic stability, and cell survival. Together, these observations indicate that USP11 is a chromatin modifier critically involved in DNA damage response and the maintenance of genomic stability.

  2. USP11 depletion suppresses cell proliferation and wound healing in lung epithelial cells, and these effects are reversed by E2F1 and PEG10 overexpression.

  3. A crystal structure of a USP11-peptide complex revealed a previously unknown binding site in USP11's noncatalytic ubiquitin-like region.

  4. modulating USP11 expression altered the stability of TGFb receptor type II (TGFBR2) and TGFb downstream signaling in human breast cancer cells. Together, these data suggest that deubiquitination of TGFBR2 by USP11 effectively spares TGFBR2 from proteasomal degradation to promote EMT and metastasis

  5. Studied ubiquitin specific peptidase 11 (USP11) expression in hepatocellular carcinoma in clinical samples, in vivo and in vitro; found USP11 upregulated HCC cell invasion, migration ability and results suggest USP11 promotes HCC tumor invasion through inducing angiogenesis.

  6. Study results revealed that USP11 promoted epithelialtomesenchymal transition in ovarian cancer by deubiquitinating Snail, and USP11 may be a novel therapeutic target for ovarian cancer treatment.

  7. FASN-induced S6 kinase facilitates USP11-eIF4B complex formation for sustained oncogenic translation in diffuse large B-cell lymphoma.

  8. These findings reveal an important mechanism by which p21 can be stabilized by direct deubiquitylation, and they pinpoint a crucial role of the USP11-p21 axis in regulating cell-cycle progression and DNA damage responses.

  9. show that USP11 is associated with the mitotic spindle, does not regulate SAC inactivation, but controls ubiquitination of RAE1 at the mitotic spindle, hereby functionally modulating its interaction with Nuclear Mitotic Apparatus protein (NuMA)

  10. High USP11 expression is associated with cancer.

  11. USP11 may contribute to the pathogenesis of pulmonary fibrosis by stabilization of TbetaRII and promotion of TGFbeta-1 signaling.

  12. We demonstrated that, while depletion of XIAP attenuates cell transformation, elevated USP11 significantly promotes the tumor colony formation through stabilization of XIAP.

  13. These findings elucidate deeply and extensively the mechanism of RNF8/RNF168 and USP11 to maintain the proper status of ubiquitylation gammaH2AX to repair double strand breaks.

  14. novel insight into cross-talk between ubiquitin and SUMO and uncover USP11 and RNF4 as a balanced SUMO-targeted ubiquitin ligase/protease pair with a role in the DDR.

  15. PML degradation mechanism through Notch/Hey1-induced repression of USP11 involved in brain tumour pathogenesis

  16. USP11 is a novel regulator of p53, which is required for p53 activation in response to DNA damage

  17. Our data support a model whereby USP11 domains outside the catalytic core domain serve as protein interaction or trafficking modules rather than a direct regulatory function of the proteolytic activity.

  18. USP-11 is not a predictor of a pCR after anthracycline-taxane-containing NST for breast cancer. Low USP-11 expression was independently correlated with better survival outcomes.

  19. USP11 augments TGFbeta signalling by deubiquitylating ALK5.

  20. Ablation of either USP7 or USP11 in primary human fibroblasts results in de-repression of the INK4a tumour suppressor accompanied by loss of Polycomb repressive complex 1 binding at the locus and a senescence-like proliferative arrest.

Mouse (Murine) Ubiquitin Specific Peptidase 11 (USP11) Interaktionspartner

  1. USP11 may contribute to the pathogenesis of pulmonary fibrosis by stabilization of TbetaRII and promotion of TGFbeta-1 signaling.

  2. USP11 augments TGFbeta signalling by deubiquitylating ALK5.

  3. structural and functional characterization of the USP11 deubiquitinating enzyme

USP11 Antigen-Profil

Protein Überblick

Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases that specifically cleave ubiquitin from ubiquitin-conjugated protein substrates. This gene encodes a deubiquitinating enzyme which lies in a gene cluster on chromosome Xp11.23

Genbezeichner und Symbole assoziert mit USP11

  • ubiquitin specific peptidase 11 (USP11) Antikörper
  • universal stress protein (RR_RS19935) Antikörper
  • ubiquitin specific peptidase 11 (Usp11) Antikörper
  • 6230415D12Rik Antikörper
  • DKFZp459L098 Antikörper
  • mKIAA4085 Antikörper
  • Uhx1 Antikörper
  • USP11 Antikörper

Bezeichner auf Proteinebene für USP11

ubiquitin carboxyl-terminal hydrolase 11 , ubiquitin specific protease 11 , ubiquitin specific peptidase 11 , universal stress protein , deubiquitinating enzyme 11 , ubiquitin carboxyl-terminal hydrolase, X-linked , ubiquitin thioesterase 11 , ubiquitin thiolesterase 11 , ubiquitin-specific processing protease 11 , ubiquitin-specific-processing protease 11 , mucin

GENE ID SPEZIES
538948 Bos taurus
706555 Macaca mulatta
3130687 Haloarcula marismortui ATCC 43049
100051171 Equus caballus
100172618 Pongo abelii
100595071 Nomascus leucogenys
8237 Homo sapiens
236733 Mus musculus
404014 Canis lupus familiaris
408217 Rattus norvegicus
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