Tyrosinase  Proteine (TYR)

The enzyme encoded by TYR catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. Zusätzlich bieten wir Ihnen Tyrosinase  Antikörper (279) und Tyrosinase  Kits (65) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
TYR 7299 P14679
TYR 22173 P11344
TYR 308800  
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Top Tyrosinase  Proteine auf antikoerper-online.de

Showing 10 out of 15 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 50 bis 55 Tage
$5,262.31
Details
Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 50 bis 55 Tage
$7,493.38
Details
Escherichia coli (E. coli) Wildschwein His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$704.00
Details
Escherichia coli (E. coli) Human His-SUMO Tag 100 μg Anmelden zum Anzeigen 11 Days
$411.40
Details
Hefe Human His tag 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
$484.00
Details
Escherichia coli (E. coli) Schwein Unkonjugiert SDS-PAGE analysis of Pig Tyrosinase Protein. 100 μg Anmelden zum Anzeigen 11 bis 18 Tage
$639.61
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$814.00
Details
Wheat germ Human GST tag 2 μg Anmelden zum Anzeigen 11 bis 12 Tage
$338.33
Details
Hefe Cat His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,113.83
Details
Hefe REACT_Pelodiscus sinensis japonicus His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,656.50
Details

TYR Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , ,
, , , ,
Mouse (Murine)
,
Rat (Rattus)

Weitere Proteine zu Tyrosinase  (TYR) Interaktionspartnern

Zebrafish Tyrosinase  (TYR) Interaktionspartner

  1. Retinal pigment epithelium (which normally expresses tyrosinase) secretes a modulatory factor, possibly L-DOPA, which regulates light adaptation in the retinal circuitry.

Atlantic Salmon (Salmo salar) Tyrosinase  (TYR) Interaktionspartner

  1. Transcription of the tyrosinase gene family in an Atlantic salmon leukocyte cell line (SHK-1) is influenced by temperature, but not by virus infection or bacterin stimulation.

Human Tyrosinase  (TYR) Interaktionspartner

  1. Membrane-associated human tyrosinase is an enzymatically active monomeric glycoprotein.

  2. The effect of histidine mutations on the structural stability of human tyrosinase leading to albinism has been reported.

  3. Compound heterozygous mutations (c.832C>T and c.929_930insC) in the TYR gene may be responsible for partial clinical manifestations of oculocutaneous albinism

  4. Mutations in tyrosinase gene is associated with Oculocutaneous albinism type 1.

  5. tyrosinase as a potential GPR143 binding protein opens new avenues for investigating the mechanisms that regulate pigmentation and neurogenesis.

  6. Aberrant tyrosinase expression in an atypical fibroxanthoma

  7. Findings suggested that miR-330-5p represents a potential tumor-suppressive miRNA and plays an important role in cutaneous malignant melanoma progression by suppressing TYR and PDIA3 expression.

  8. Four missense substitutions (p.Arg239Trp, p.Ser192Tyr, p.Ser44Arg and p.Arg77Gln) were identified in tyrosinase in the families with oculocutaneous albinism linkage, and another missense substitution (p.Gln272Lys) was identified in the family with OCA4 linkage

  9. LEF-1 and MITF regulate tyrosinase gene transcription in vitro via binding to its promoter.

  10. Data show that mutant microphthalmia-associated transcription factor (MITF) with loss of localization signals (NLS) has failed to transactivate the transcriptional activities of target gene tyrosinase (TYR), which can cause Waardenburg syndrome.

  11. The tyrosinase gene was examined in 23 unrelated patients with autosomal recessive ocular albinism or nonsyndromic oculocutaneous albinism. TYR gene mutations were identi fi ed in 14 (app. 60%) albinism patients.

  12. The two mutations (c.1114delG in the TYR gene and c.1426A>G in the OCA2 gene) may be responsible for partial clinical manifestations of Oculocutaneous albinism.

  13. Molecular analysis identified two compound heterozygous TYR mutations known to cause OCAIA and cosegregate with oculocutaneous albinism. In addition, we identified a novel heterozygous PAX6 mutation confirming the atypical aniridia phenotype.

  14. Overall, our data strongly suggest that IRF4, MC1R and TYR genes likely have pleiotropic effects, a combination of pigmentation and oncogenic functions, resulting in an increased risk of actinic keratosis.

  15. Data indicate that tyrosinase is used as a reporter gene owing to its strong optical absorption and enzymatic amplification mechanism and melamin production.

  16. Identification of four novel TYR mutations in a Chinese Han population with Oculocutaneous albinism 1.

  17. 11/11 individuals with homozygous or compound heterozygous mutations in TYR, have no discernible pigmentation in hair, skin and eyes

  18. human tyrosinase, which can oxidize l-tyrosine but not d-tyrosine, was found to oxidize both R(-)- and S(+)-rhododendrol.

  19. Among the 24 (58.5%) patients with OCA1, 21 different TYR mutations were identified, including three previously unidentified alleles

  20. Two new pathogenic p.C89S and p.H180R mutations in TYR were detected in two OCA1 patients.

Rabbit Tyrosinase  (TYR) Interaktionspartner

  1. the 3' UTR of the rabbit Tyr gene was deleted by a dual sgRNA directed CRISPR/Cas9 system which resulted in gray coat color and reduced melanin in hair follicles and irises was found in the mutated rabbit.

  2. we identified some genes that are related to fur formation, including Tyrosinase-related protein 1 (TYRP1) and Tyrosinase (TYR), as well as genes with unknown functions.

Tyrosinase  (TYR) Protein Überblick

Protein Überblick

The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene.

Genbezeichner und Symbole assoziert mit Tyrosinase  Proteine (TYR)

  • tyrosinase (tyr)
  • TYRosinase (tyr-5)
  • tyrosinase S homeolog (tyr.S)
  • tyrosinase (TYR)
  • tyrosinase (Celal_3121)
  • tyrosinase (Halhy_4121)
  • tyrosinase (Mesop_2736)
  • tyrosinase (LOC100136546)
  • tyrosinase (Tyr)
  • albino Protein
  • C Protein
  • CMM8 Protein
  • LOC100136546 Protein
  • OCA1A Protein
  • OCAIA Protein
  • sandy Protein
  • SHEP3 Protein
  • skc35 Protein
  • tyr Protein
  • TYRO Protein
  • zgc:109705 Protein

Bezeichner auf Proteinebene für Tyrosinase  Proteine (TYR)

oca1 , sdy , tyra , hypothetical protein , tyrosinase (oculocutaneous albinism IA) , tyrosinase , monophenol monooxygenase , tyrosinase-like , LB24-AB , SK29-AB , oculocutaneous albinism IA , tumor rejection antigen AB , albino locus protein

GENE ID SPEZIES
30207 Danio rerio
189907 Caenorhabditis elegans
398715 Xenopus laevis
451473 Pan troglodytes
705792 Macaca mulatta
10145547 Cellulophaga algicola DSM 14237
10588308 Haliscomenobacter hydrossis DSM 1100
10826573 Mesorhizobium opportunistum WSM2075
100049427 Oryzias latipes
100125152 Xenopus (Silurana) tropicalis
100135825 Oncorhynchus mykiss
100136546 Salmo salar
100453479 Pongo abelii
100594055 Nomascus leucogenys
7299 Homo sapiens
22173 Mus musculus
308800 Rattus norvegicus
100713552 Cavia porcellus
403405 Canis lupus familiaris
751100 Felis catus
100008753 Oryctolagus cuniculus
407745 Sus scrofa
280951 Bos taurus
373971 Gallus gallus
780502 Ovis aries
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