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TUSC1 is located within the region of chromosome 9p that harbors tumor suppressor genes critical in carcinogenesis. Zusätzlich bieten wir Ihnen und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal TUSC1 Primary Antibody für IF (p), IHC (p) - ABIN762641
Kanda, Shimizu, Nomoto, Hibino, Oya, Takami, Kobayashi, Yamada, Inokawa, Tanaka, Fujii, Sugimoto, Koike, Fujiwara, Kodera: Clinical significance of expression and epigenetic profiling of TUSC1 in gastric cancer. in Journal of surgical oncology 2014
Show all 2 Pubmed References
The expression of TUSC1 is significantly decreased in glioblastoma brain tumor tissues.
TUSC1 is a candidate tumor suppressor gene and intragenic hypermethylation is one of the suppressive mechanisms that regulate TUSC1 transcription in hepatocellular carcinoma.
Results suggested that reduced expression of TUSC1 mRNA was related to poor prognosis and TUSC1 is a putative tumor suppressor gene that is suppressed through intragenic hypermethylation in gastric cancer.
Results support TUSC1 has tumor suppressor activity as a candidate tumor suppressor gene located on chromosome 9p.
TUSC1 may play a role in lung tumorigenesis
This gene is located within the region of chromosome 9p that harbors tumor suppressor genes critical in carcinogenesis. It is an intronless gene which is downregulated in non-small-cell lung cancer and small-cell lung cancer cell lines, suggesting that it may play a role in lung tumorigenesis.
tumor suppressor candidate gene 1 protein
, tumor suppressor candidate gene 1 protein homolog
, tumour suppressor candidate 1