anti-Tryptase beta 2 (Gene/pseudogene) (TPSB2) Antikörper

Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Zusätzlich bieten wir Ihnen und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
Anti-Maus TPSB2 TPSB2 17229  
Anti-Ratte TPSB2 TPSB2 29268 P50343
Anti-Human TPSB2 TPSB2 64499 P20231
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Weitere Antikörper gegen TPSB2 Interaktionspartner

Mouse (Murine) Tryptase beta 2 (Gene/pseudogene) (TPSB2) Interaktionspartner

  1. These data indicate that endogenous mMCP6 has scar-suppressing properties after spinal cord injury via indirect cleavage of axon growth-inhibitory scar components and alteration of the gene expression profile of these factors.

  2. Inflammatory Th2 responses can develop independently of MCP-6, whereas MCP-6 plays a key role in the development of airway hyperresponsiveness.

  3. Tryptase (zeige TPSAB1 Antikörper)-beta was capable of inducing pelvic pain and was increased in experimental autoimmune prostatitis.

  4. mast cell tryptase, a serglycin proteoglycan (zeige SRGN Antikörper)-dependent secretory granule protease, has a role in proteolytic histone modification

  5. Trypase can promote atherosclerotic plaque haemorrhage by promoting angiogenesis and regulating the balance of PAI-1 (zeige SERPINE1 Antikörper) and tPA (zeige PLAT Antikörper).

  6. This study demonstrates for the first time that an mast cell-restricted tetramer-forming tryptase (zeige TPSAB1 Antikörper) has a prominent adverse role in experimental chronic obstructive pulmonary disease

  7. this study indicates that mast cells may be a source of TGF-beta (zeige TGFB1 Antikörper) production after cigarette smoke exposure and that in turn TGF-beta (zeige TGFB1 Antikörper) may change the tryptase (zeige TPSAB1 Antikörper) expression in mast cells.

  8. MCP6 actively depletes the local environment of IL-6 (zeige IL6 Antikörper) to maintain tolerance in mice.

  9. MCP-6 (but not MCP-7 (zeige TPSAB1 Antikörper)) is an essential mast cell-restricted mediator in chemically induced colitis and acts upstream of many of the factors implicated in inflammatory bowel disease.

  10. mast cell mMCP-4, -5, and -6 (chymase (zeige CMA1 Antikörper) and tryptase (zeige TPSAB1 Antikörper)) participate in the acute inflammation and remodeling process of viral myocarditis.

Human Tryptase beta 2 (Gene/pseudogene) (TPSB2) Interaktionspartner

  1. These observations indicate that betaII-tryptase (zeige TPSAB1 Antikörper) activity is post-translationally regulated by an allosteric disulfide bond.

  2. Results indicate a key role for heparin in the activation of human betaI- and beta2-tryptase (zeige TPSAB1 Antikörper).

  3. The disease severity and plasma tryptase (zeige TPSAB1 Antikörper) levels were not affected by the number of alpha or beta tryptase (zeige TPSAB1 Antikörper) alleles in mastocytosis patients.

  4. Strong linkage of TPSAB1 (zeige TPSAB1 Antikörper) and TPSB2 and pairing of deficiency alleles with functional alleles in observed haplotypes protect human subjects from "knockout" genomes and indeed from inheritance of fewer than 2 active alleles.

TPSB2 Antigen-Profil

Protein Überblick

Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate genes, beta II and beta III. Beta tryptases appear to be the main isoenzymes expressed in mast cells, whereas in basophils, alpha-tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders.

Genbezeichner und Symbole assoziert mit TPSB2

  • tryptase beta 2 (Tpsb2) Antikörper
  • tryptase beta 2 (gene/pseudogene) (TPSB2) Antikörper
  • AV011504 Antikörper
  • Mcp-6 Antikörper
  • Mcp6 Antikörper
  • Mcpt6 Antikörper
  • MMCP-6 Antikörper
  • TPS2 Antikörper
  • tryptaseB Antikörper
  • tryptaseC Antikörper

Bezeichner auf Proteinebene für TPSB2

mast cell protease 6 , tryptase beta-2 , tryptase-2 , rMCP-6 , mast cell tryptase beta II , mast cell tryptase beta III

17229 Mus musculus
29268 Rattus norvegicus
64499 Homo sapiens
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