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The protein encoded by TRIM2 is a member of the tripartite motif (TRIM) family. Zusätzlich bieten wir Ihnen TRIM2 Antikörper (102) und TRIM2 Kits (2) und viele weitere Produktgruppen zu diesem Protein an.
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TRIM2 is associated with clinical fibrotic phenotypes of eosinophilic esophagitis.
We found that CREBRF (zeige CREBRF Proteine) and TRIM2 mRNA were significantly upregulated by rHDL, particularly in response to its phospholipid component 1-palmitoyl-2-linoleoyl-phosphatidylcholine (zeige SGMS2 Proteine), however, protein expression was not significantly altered.
Studies indicate most-studied TRIpartite Motif (TRIM (zeige TRAT1 Proteine))-NHL proteins TRIM2, TRIM3 (zeige TRIM3 Proteine), TRIM32 (zeige TRIM32 Proteine) and TRIM71 (zeige TRIM71 Proteine), and their mutations have been linked to diseases.
TRIM2 homozygous missense mutation (c.2000A>C; p.D667A) in a patient with peripheral neuropathy and bilateral vocal cord paralysis
The functional role of the C-terminal NHL domain was characterized in TRIM2.
TRIM2 is repressed by miR (zeige MLXIP Proteine)-9 and -181c, either alone or in combination.
a role for TRIM2 in mediating the p42/p44 (zeige PSMC6 Proteine) MAPK (zeige MAPK3 Proteine)-dependent ubiquitination of Bim (zeige BCL2L11 Proteine) in rapid ischemic tolerance.
Trim2 has an important function in the regulation of axon outgrowth during development.
TRIM2 is an ubiquitin ligase and point to a mechanism regulating neurofilament light subunit metabolism through an ubiquitination pathway that, if deregulated, triggers neurodegeneration
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic filaments. Its function has not been identified.
E3 ubiquitin-protein ligase TRIM2
, RING finger protein 86
, tripartite motif protein 2
, tripartite motif protein TRIM2
, tripartite motif-containing 2
, tripartite motif-containing protein 2
, neural activity-related ring finger protein
, Tripartite motif-containing protein 2
, tripartite motif containing 2 S homeolog
, tripartite motif containing 2