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The protein encoded by TRIM2 is a member of the tripartite motif (TRIM) family. Zusätzlich bieten wir Ihnen TRIM2 Antikörper (94) und TRIM2 Kits (2) und viele weitere Produktgruppen zu diesem Protein an.
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Study revealed that TRIM2 performs important functions in regulating the development and metastasis of osteosarcoma.
TRIM2 is associated with clinical fibrotic phenotypes of eosinophilic esophagitis.
We found that CREBRF and TRIM2 mRNA were significantly upregulated by rHDL, particularly in response to its phospholipid component 1-palmitoyl-2-linoleoyl-phosphatidylcholine, however, protein expression was not significantly altered.
Studies indicate most-studied TRIpartite Motif (TRIM)-NHL proteins TRIM2, TRIM3, TRIM32 and TRIM71, and their mutations have been linked to diseases.
TRIM2 homozygous missense mutation (c.2000A>C; p.D667A) in a patient with peripheral neuropathy and bilateral vocal cord paralysis
The functional role of the C-terminal NHL domain was characterized in TRIM2.
TRIM2 is repressed by miR-9 and -181c, either alone or in combination.
a role for TRIM2 in mediating the p42/p44 MAPK-dependent ubiquitination of Bim in rapid ischemic tolerance.
Trim2 has an important function in the regulation of axon outgrowth during development.
TRIM2 is an ubiquitin ligase and point to a mechanism regulating neurofilament light subunit metabolism through an ubiquitination pathway that, if deregulated, triggers neurodegeneration
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic filaments. Its function has not been identified.
E3 ubiquitin-protein ligase TRIM2
, RING finger protein 86
, tripartite motif protein 2
, tripartite motif protein TRIM2
, tripartite motif-containing 2
, tripartite motif-containing protein 2
, neural activity-related ring finger protein
, Tripartite motif-containing protein 2
, tripartite motif containing 2 S homeolog
, tripartite motif containing 2