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Regulates the distribution of TOR1A between the endoplasmic reticulum and the nuclear envelope (By similarity)..
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A comparison of these structures shows, in atomic detail, the subtle differences in TorsinADeltaE-LULL1 activator interactions that separate the healthy from the diseased state.
The Torsin Activator LULL1 Is Required for Efficient Growth of Herpes Simplex Virus 1.
LAP1 (zeige ANPEP Antikörper) and LULL1 regulate Torsin ATPase (zeige DNAH8 Antikörper) activity through an active site complementation mechanism.
LAP1 (zeige ANPEP Antikörper) and LULL1 as regulatory cofactors that are responsible for the activation of TorA's ATPase (zeige DNAH8 Antikörper) activity.
identifed a novel transmembrane protein, lumenal domain like LAP1 (LULL1), which appears to interact with torsinA (zeige TOR1A Antikörper); it resides in the main endoplasmic reticulum.
Data suggest that LULL1 regulates the distribution and activity of TorA within the ER and NE lumen and reveal functional defects in the mutant protein responsible for DYT1 (zeige TOR1A Antikörper) dystonia.
Preimplantation embryo development was arrested at the 1-cell stage after knocking down Ifrg15 expression.
The data suggest that LULL1 oligomerizes to engage and transiently disassemble torsinA (zeige TOR1A Antikörper) oligomers, and is thereby positioned to transduce cytoplasmic signals to the inner nuclear membrane through torsinA (zeige TOR1A Antikörper).
Ifrg15 transcription might be either potentially regulated or dependent on the post-transcriptional effects of IFN-alpha mediated by the three genes Oct4, c-Myc and Nanog indirectly
These results suggest that Ifrg15 is closely related to odontogenesis, especially the differentiation of the ameloblasts and odontoblasts, and to the morphogenesis of the craniofacial organs.
Regulates the distribution of TOR1A between the endoplasmic reticulum and the nuclear envelope (By similarity).
torsin A interacting protein 2
, interferon alpha responsive
, interferon responsive gene 15
, lumenal domain like LAP1
, lumenal domain-like LAP1
, torsin-1A-interacting protein 2
, interferon alpha responsive gene, 15 kDa
, interferon alpha responsive protein (15 kDa)
, interferon alpha responsive protein; torsin-1A-interacting protein 2