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The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. Zusätzlich bieten wir Ihnen Thrombomodulin Antikörper (267) und Thrombomodulin Proteine (25) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 98 products:
Mouse (Murine) Thrombomodulin ELISA Kit für Sandwich ELISA - ABIN424235
Raeven, Salibasic, Drechsler, Weixelbaumer, Jafarmadar, van Griensven, Bahrami, Osuchowski: A non-lethal traumatic/hemorrhagic insult strongly modulates the compartment-specific PAI-1 response in the subsequent polymicrobial sepsis. in PLoS ONE 2013
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Human Thrombomodulin ELISA Kit für Sandwich ELISA - ABIN415045
Tsimaris, Deligeoroglou, Athanasopoulos, Economou, Stamatelopoulos, Rizos, Papamichael, Lambrinoudaki, Mastorakos, Creatsas: The effect of hormone therapy on biochemical and ultrasound parameters associated with atherosclerosis in 46,XY DSD individuals with female phenotype. in Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2014
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Rat (Rattus) Thrombomodulin ELISA Kit für Sandwich ELISA - ABIN368176
Yamakawa, Matsumoto, Imamura, Muroya, Yamada, Nakagawa, Shimazaki, Ogura, Kuwagata, Shimazu: Electrical vagus nerve stimulation attenuates systemic inflammation and improves survival in a rat heatstroke model. in PLoS ONE 2013
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Human Thrombomodulin ELISA Kit für Sandwich ELISA - ABIN1445996
Akil, Zhang, Mumaw, Raiker, Yu, Velez de Mendizabal, Haneline, Robertson, Skiles, Diaz-Ricart, Carreras, Renbarger, Hanash, Bies, Paczesny: Biomarkers for Diagnosis and Prognosis of Sinusoidal Obstruction Syndrome after Hematopoietic Cell Transplantation. in Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2015
Dog (Canine) Thrombomodulin ELISA Kit für Sandwich ELISA - ABIN416633
Kuleš, Gotić, Mrljak, Barić Rafaj: Blood markers of fibrinolysis and endothelial activation in canine babesiosis. in BMC veterinary research 2017
Rat (Rattus) Thrombomodulin ELISA Kit für Sandwich ELISA - ABIN416379
Kaija, Pakanen, Uusitalo, Nikkilä, Kortelainen, Porvari: Changes in cardiac thrombomodulin and heat shock transcription factor 1 expression and peripheral thrombomodulin and catecholamines during hypothermia in rats. in Stress (Amsterdam, Netherlands) 2014
TM, especially TME45, maintains vascular integrity, at least in part, via Src (zeige SRC ELISA Kits) signaling.
The present study found that the fifth epidermal growth factor (zeige EGF ELISA Kits)-like domain of thrombomodulin (TME5) possesses the cytoprotective function in association with an increase in levels of anti-apoptotic myeloid cell leukemia-1 protein in an activated protein C (zeige PROC ELISA Kits)-independent
Case Report: CD141+ myeloid dentritic cell differentiation of a juvenile myelomonocytic leukemia.
The finding of a previously unrecognized fibrinolytic phenotype indicates that bleeding in Thrombomodulin-associated coagulopathy has a complex pathogenesis and highlights the pivotal role of TM as a regulator of hemostasis.
TM mediates cell proliferation and migration via the Epithelial-To-Mesenchymal Transition (EMT (zeige ITK ELISA Kits)) biomarkercyclooxygenase (COX)-2 (zeige COX2 ELISA Kits)
the whole THBD gene sequenced in patients with recurrent venous thromboembolism (VTE); found 8 polymorphisms in the THBD gene in Swedish population; none of these polymorphisms was significantly associated with the risk of VTE recurrence; results indicate that THBD polymorphisms may not be a risk factor for VTE recurrence
CORM-2 protects human umbilical vein endothelial cells from lipopolysaccharide-induced injury, by way of suppressing NF-kappaB (zeige NFKB1 ELISA Kits) activity, which downregulates TM and EPCR (zeige PROCR ELISA Kits) mRNAs. It also decreases MMP-2 (zeige MMP2 ELISA Kits) expression and prevents the shedding of TM and EPCR (zeige PROCR ELISA Kits) from the surface of endothelial cells, so as to preserve their protective effect.
The results demonstrate that the LFA-1 (zeige ITGAL ELISA Kits) and Mac-1 (zeige ITGAM ELISA Kits) integrins on leukocytes bind to thrombomodulin (TM), thereby establishing the molecular and structural basis underlying LFA-1 (zeige ITGAL ELISA Kits) and Mac-1 (zeige ITGAM ELISA Kits) integrin interaction with TM on endothelial cells.
Human thrombomodulin transgenic aortic endothelial cells are less sensitive to activation by either HMGB1 or hTNFalpha, an effect that appears to be dependent on the lectin-like domain of TBM.
In placenta of patients with preeclampsia, we detected abnormal expression of F3 and THBD with increased protein and mRNA levels. The role of these molecules in the pathogenesis of this disease and in alterations of hemostatic and histopathological aspects of placentas need further studying.
the lectin-like domain of thrombomodulin is critically involved in host defence against E. coli induced acute pyelonephritis
Identified Nur77 (zeige NR4A1 ELISA Kits)/Nor1 (zeige NR4A3 ELISA Kits) as novel regulators of thrombomodulin expression and function in vascular endothelial cells.
TM expression in corneal epithelium was modulated during the corneal wound healing process, and may be regulated by PDGF (zeige PDGFA ELISA Kits)-BB. In addition, rTMD23 has therapeutic potential in corneal injury
Thrombomodulin contributes to gamma tocotrienol-mediated lethality protection and hematopoietic cell recovery in irradiated mice
the recombinant epidermal growth factor (zeige EGF ELISA Kits)-like domain plus serine/threonine-rich domain of thrombomodulin suppresses the inflammatory response in mice
Thrombomodulin may modulate allergic responses by inhibiting the activation of both eosinophils and mast cells.
Thrombomodulin modulates dendritic cells via both antagonism of high mobility group protein B1 (zeige HMGB1 ELISA Kits) and an independent mechanism.
The lectin-like domain of TM does not play an important role in the host response to M. tuberculosis infection in mice.
Recombinant thrombomodulin protects mice against histone-induced lethal thromboembolism.
Atorvastin induces THBD expression in the aorta of cholesterol-fed rabbits.
The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia.
, CD141 antigen
, snoRNA MBII-339