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TSPAN32, which is a member of the tetraspanin superfamily, is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of chromosome 11p15.5, an important tumor-suppressor gene region. Zusätzlich bieten wir Ihnen TSPAN32 Antikörper (54) und viele weitere Produktgruppen zu diesem Protein an.
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In the absence of both CD37 (zeige TSPAN26 Proteine) and Tssc6, immune function is further altered when compared with CD37 (zeige TSPAN26 Proteine)- or Tssc6-deficient transgenic mice, demonstrating a complementary role for these two molecules in cellular immunity.
Study demonstrates a complementary role between TSSC6 and P2Y12 (zeige P2RY12 Proteine) receptor in platelets in regulating 'outside in' integrin alphaIIbbeta3 signalling thrombus growth and stability.
The absence of Tssc6, a member of the tetraspanin superfamily, does not affect lymphoid development but enhances in vitro T-cell proliferative responses.
absence of platelet TSSC6 affects the secondary stability of arterial thrombi in vivo upon vascular injury
This gene, which is a member of the tetraspanin superfamily, is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of chromosome 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian and breast cancers. This gene is located among several imprinted genes\; however, this gene, as well as the tumor-suppressing subchromosomal transferable fragment 4, escapes imprinting. This gene may play a role in malignancies and diseases that involve this region, and it is also involved in hematopoietic cell function. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
, pan-hematopoietic expression protein
, protein Phemx
, tumor-suppressing STF cDNA 6
, tumor-suppressing subchromosomal transferable fragment cDNA 6
, tumor-suppressing subtransferable candidate 6
, AML1-regulated transmembrane protein 1
, pan hematopoietic expression
, tumor-suppressing subchromosomal transferable fragment 6