Tensin 3 Proteine (TNS3)

May play a role in actin remodeling. Zusätzlich bieten wir Ihnen Tensin 3 Antikörper (24) und Tensin 3 Kits (5) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
Ratte TNS3 TNS3 360980  
TNS3 319939 Q5SSZ5
TNS3 64759 Q68CZ2
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Showing 3 out of 3 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
Escherichia coli (E. coli) Human T7 tag,His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage

TNS3 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine)

Human ,

Weitere Proteine zu Tensin 3 (TNS3) Interaktionspartnern

Mouse (Murine) Tensin 3 (TNS3) Interaktionspartner

  1. Dock5 and tensin 3 cooperate for osteoclast activity, to ensure the correct organization of podosomes.

  2. Tensin3 is a versatile regulator of DOCK5 signaling and cell adhesion. (Review)

  3. Results indicate that tensin3 is essential for normal development and functions of the small intestine, lung, and bone [tensin3].

  4. Tns3 protein, including its SH2 domain, is phosphorylated by Src and contributes to tumorigenesis and metastasis.

Human Tensin 3 (TNS3) Interaktionspartner

  1. These findings suggested a critical role of MSI1-TNS3 axis in regulating glioblastoma migration.

  2. Our work identifies Tns3 as a crucial focal adhesion component regulated by, and functionally contributing to, the switch between adhesive and non-adhesive states in MDA-MB-468 cancer cells.

  3. A phosphorylation-mediated molecular switch comprising DLC), TNS3, PTEN and PI3K controls the spatiotemporal activation of Rac1 and RhoA, thereby initiating directional cell migration induced by growth factors.

  4. The depletion of tensin-3 suppressed breast cancer cell invasiveness.

  5. The phenotypic changes observed in proband cells may arise from TNS3 haploinsufficiency, causing partial loss of full-length Tensin3 protein. Tensin3 plays a rol in cytoskeletal organisation and cell motility.

  6. These results reveal a differential methylation pattern in the TNS3 promoter occurring in human renal cell carcinoma.

  7. Tensin3 may function as a platform for the disassembly of EGF-related signaling complexes at focal adhesions.

  8. Data show that EGF downregulates tensin-3 expression, and concomitantly upregulates cten, a tensin family member that lacks the actin-binding domain.

  9. TNS3-EXOC6B and EXOC6B-TNS3 fusion transcripts are detected in a premature male newborn with a complex multisystemic phenotype associated with a balanced translocation.

  10. Tensin3 mRNA is expressed abundantly in all twelve functional adenomas at almost the same level as in normal thyroid tissue.

  11. Tensins may represent a novel group of metastasis suppressors in the kidney, the loss of which leads to greater tumor cell motility and consequent metastasis.

Tensin 3 (TNS3) Protein Überblick

Protein Überblick

May play a role in actin remodeling. Involved in the dissociation of the integrin-tensin-actin complex. EGF activates TNS4 and down-regulates TNS3 which results in capping the tail of ITGB1. Seems to be involved in mammary cell migration (By similarity). May be involved in cell migration and bone development.

Genbezeichner und Symbole assoziert mit Tensin 3 Proteine (TNS3)

  • tensin 3 (Tns3)
  • tensin 3 (TNS3)
  • tensin-3 (LOC100539445)
  • BC023928 Protein
  • F830010I22Rik Protein
  • RGD1564174 Protein
  • TEM6 Protein
  • TENS1 Protein
  • tensin3 Protein
  • TSN3 Protein

Bezeichner auf Proteinebene für Tensin 3 Proteine (TNS3)

tensin 3 , Temporarily Assigned Gene name family member (tag-163)-like , tensin-3-like , tensin-3 , tensin-like SH2 domain containing 1 , tensin-like SH2 domain-containing protein 1 , tumor endothelial marker 6 , tensin-like SH2 domain-containing 1 , thyroid specific PTB domain protein

360980 Rattus norvegicus
463400 Pan troglodytes
516555 Bos taurus
100065955 Equus caballus
100397895 Callithrix jacchus
100539445 Meleagris gallopavo
319939 Mus musculus
64759 Homo sapiens
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