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TAS2R1 encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily and that are specifically expressed by taste receptor cells of the tongue and palate epithelia. Zusätzlich bieten wir Ihnen und viele weitere Produktgruppen zu diesem Protein an.
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TAS2R agonists block signaling downstream of phosphatidylinositol 3-kinase
Expression and functional activity of the bitter taste receptors TAS2R1 and TAS2R38 in human keratinocytes
Intracellular signaling and cell mechanics using isolated human airway smooth muscle, mouse tracheal responses, and human bronchial responses to characterize TAS2R relaxation in the context of beta(2)AR desensitization.
The formation of a short helical segment in intracellular loop II may be necessary for the activation of hTAS2R1.
Structural basis of activation of bitter taste receptor T2R1 and comparison with Class A G-protein-coupled receptors (GPCRs).
The ligand binding pocket in T2R1 is present on the extracellular surface of the receptor, and is formed by the transmembrane helices 1, 2, 3 and 7 and with extracellular loops 1 and 2 forming a cap like structure on the binding pocket.
This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily and that are specifically expressed by taste receptor cells of the tongue and palate epithelia. This intronless taste receptor gene encodes a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is mapped to chromosome 5p15, the location of a genetic locus (PROP) that controls the detection of the bitter compound 6-n-propyl-2-thiouracil.
taste receptor family B member 7
, taste receptor type 2 member 1
, taste receptor, family B, member 7
, bitter taste receptor Bota-T2R1
, taste receptor T2R1