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TIMP4 belongs to the TIMP gene family. Zusätzlich bieten wir Ihnen TIMP4 Antikörper (203) und TIMP4 Kits (68) und viele weitere Produktgruppen zu diesem Protein an.
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Human TIMP4 Protein expressed in Wheat germ - ABIN1322795
Boström, Wu, Jedrychowski, Korde, Ye, Lo, Rasbach, Boström, Choi, Long, Kajimura, Zingaretti, Vind, Tu, Cinti, Højlund, Gygi, Spiegelman: A PGC1-?-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. in Nature 2012
MMP2 (zeige MMP2 Proteine)/TIMP4 ratio is a marker of disease severity and right ventricular function as well as a predictor for survival and time to clinical worsening in idiopathic pulmonary arterial hypertension.
Aspirin-HPR (zeige HPR Proteine) did not affect the translocation and release of MMPs and TIMP-4 from platelets.
Combining two biomarkers significantly improved discrimination of AHRE (zeige AHR Proteine). CONCLUSION: TIMP-4, NT-proANP, NT-proBNP were strongest associated with PAF (zeige PAF Proteine) and AHRE (zeige AHR Proteine). The discriminatory performance of CHADS2-VASc for PAF (zeige PAF Proteine) was increased by addition of selected biomarkers.
Our findings provide new evidence that LOX (zeige LOX Proteine) regulates SNAI2 expression and that SNAI2-mediated TIMP4 secretion plays a role in cancer progression.
This report provides the first example that TIMP-4 regulates carcinogenesis through enriching the tumor progenitor cell population in cervical cancer cells.
Study evaluated MMP-12 (zeige MMP12 Proteine) and TIMP-1 (zeige TIMP1 Proteine), TIMP-2 (zeige TIMP2 Proteine), TIMP-3 (zeige TIMP3 Proteine), and TIMP-4 levels in 40 patients with asymptomatic and symptomatic critical carotid artery stenosis (CAS (zeige CSE1L Proteine)) with neurologic symptoms onset within the preceding 12 hours; results suggest that MMP-12 (zeige MMP12 Proteine) is related to critical CAS (zeige CSE1L Proteine) independently on symptoms, moreover, TIMP-3 (zeige TIMP3 Proteine) and TIMP-4 seem to be specifically related to stroke
Concluding, miR (zeige MLXIP Proteine)-200b-3p mediates regulation of TIMP4 expression in prostate cancer but exact mechanism needs to be investigated.
TIMP1 (zeige TIMP1 Proteine), TIMP2 (zeige TIMP2 Proteine), and TIMP4 are increased in aqueous humor from primary open angle glaucoma patients.
ncreased TGFB1 (zeige TGFB1 Proteine) expression and decreased TIMP-4 expression correlated with atrial fibrosis and extracellular matrix changes in the atria of rheumatic heart disease patients with atrial fibrillation.
Upregulation of plasma TIMP-4 might contribute to PIH [pregnancy-induced hypertension] processes
there are 7 CpG islands in the TIMP4 promoter which get methylated during the progression of heart failure which leads to its epigenetic silencing.
High fat diet-induced obesity downregulates adipocyte MMP3 (zeige MMP3 Proteine) expression to trigger adipogenesis, and adipocyte TIMP4 may modulate this process to regulate hyperplastic vs. hypertrophic adipose tissue expansion, fat distribution, and metabolic health in a sex- and depot-dependent manner.
Our findings highlight a protective mechanism induced by PPARgamma (zeige PPARG Proteine) in deoxycorticosterone acetate-salt treatment, establishing a novel mechanistic link between PPARgamma (zeige PPARG Proteine) and TIMP-4.
TIMP4 augments contractility and induces differentiation of embryonic stem cells into cardiac phenotype.
TIMP-4 might act as a negative regulator of adipogenesis through NFkB cascade modulation.
Replenishment of myocardial TIMP4 could serve as an effective therapy in post-I/R recovery for patients with reduced TIMP4.
TIMP-4 protein was localized to corpus luteum and theca-intera cells in various periods throughout the pregnancy and postpartum day 1.
Timp4(-/-) mice are more susceptible to MI but not to pressure overload, and TIMP4 functions in its capacity as a metalloproteinase inhibitor after myocardial infarction
Identification of an initiator-like element essential for the expression of the tissue inhibitor of metalloproteinases-4 (Timp-4) gene
molecular cloning and localization of the gene within intron 5 of the synapsin 2 (zeige SYN2 Proteine) gene
This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The secreted, netrin domain-containing protein encoded by this gene is involved in regulation of platelet aggregation and recruitment and may play role in hormonal regulation and endometrial tissue remodeling.
TIMP metallopeptidase inhibitor 4
, tissue inhibitor of metalloproteinase 4
, metalloproteinase inhibitor 4
, tissue inhibitor of metalloproteinases 4
, tissue inhibitor of metalloproteinase
, tissue inhibitor of metalloproteinase-4