TIMP Metallopeptidase Inhibitor 4 Proteine (TIMP4)

TIMP4 belongs to the TIMP gene family. Zusätzlich bieten wir Ihnen TIMP4 Antikörper (204) und TIMP4 Kits (72) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
TIMP4 7079 Q99727
TIMP4 110595 Q9JHB3
TIMP4 680130 P81556
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Top TIMP4 Proteine auf antikoerper-online.de

Showing 10 out of 20 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
Escherichia coli (E. coli) Maus His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
Escherichia coli (E. coli) Ratte His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
Escherichia coli (E. coli) Wildschwein His tag,GST tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
Hefe Rind (Kuh) His tag TIMP Metallopeptidase Inhibitor 4 (TIMP4) (AA 30-224), (full length) protein (His tag) 500 μg Anmelden zum Anzeigen 60 bis 71 Tage
Baculovirus infected Insect Cells Maus His tag 50 μg Anmelden zum Anzeigen 13 bis 16 Tage
Hefe Human His tag 50 μg Anmelden zum Anzeigen 8 bis 11 Tage
Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 11 Days

TIMP4 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , ,
Mouse (Murine) , ,

Rat (Rattus) ,

Am meisten referenzierte TIMP4 Proteine

  1. Human TIMP4 Protein expressed in Wheat germ - ABIN1322795 : Boström, Wu, Jedrychowski, Korde, Ye, Lo, Rasbach, Boström, Choi, Long, Kajimura, Zingaretti, Vind, Tu, Cinti, Højlund, Gygi, Spiegelman: A PGC1-?-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. in Nature 2012 (PubMed)

Weitere Proteine zu TIMP Metallopeptidase Inhibitor 4 (TIMP4) Interaktionspartnern

Human TIMP Metallopeptidase Inhibitor 4 (TIMP4) Interaktionspartner

  1. MMP2/TIMP4 ratio is a marker of disease severity and right ventricular function as well as a predictor for survival and time to clinical worsening in idiopathic pulmonary arterial hypertension.

  2. Aspirin-HPR did not affect the translocation and release of MMPs and TIMP-4 from platelets.

  3. Combining two biomarkers significantly improved discrimination of AHRE. CONCLUSION: TIMP-4, NT-proANP, NT-proBNP were strongest associated with PAF and AHRE. The discriminatory performance of CHADS2-VASc for PAF was increased by addition of selected biomarkers.

  4. Our findings provide new evidence that LOX regulates SNAI2 expression and that SNAI2-mediated TIMP4 secretion plays a role in cancer progression.

  5. This report provides the first example that TIMP-4 regulates carcinogenesis through enriching the tumor progenitor cell population in cervical cancer cells.

  6. Study evaluated MMP-12 and TIMP-1, TIMP-2, TIMP-3, and TIMP-4 levels in 40 patients with asymptomatic and symptomatic critical carotid artery stenosis (CAS) with neurologic symptoms onset within the preceding 12 hours; results suggest that MMP-12 is related to critical CAS independently on symptoms, moreover, TIMP-3 and TIMP-4 seem to be specifically related to stroke

  7. Concluding, miR-200b-3p mediates regulation of TIMP4 expression in prostate cancer but exact mechanism needs to be investigated.

  8. TIMP1, TIMP2, and TIMP4 are increased in aqueous humor from primary open angle glaucoma patients.

  9. regulates carcinogenesis through apoptosis activation in cervical cancer cells

  10. ncreased TGFB1 expression and decreased TIMP-4 expression correlated with atrial fibrosis and extracellular matrix changes in the atria of rheumatic heart disease patients with atrial fibrillation.

  11. Upregulation of plasma TIMP-4 might contribute to PIH [pregnancy-induced hypertension] processes

  12. Expression levels of TIMP-1, TIMP-3 and TIMP-4 were negligible (<10% of cells) in primary spontaneous pneumothorax lesions.

  13. No evidence was found for any associations between the TIMP-1,-2,-3, or -4 gene single nucleotide polymorphisms with unexplained recurrent spontaneous abortions in this Han Chinese Han population.

  14. This study provides evidence that the promoter TIMP4 rs3755724 is a new focal epilepsy susceptibility variant that is plausibly involved in inflammation-induced seizures in Malaysian Chinese.

  15. Data show that gene polymorphisms of TIMP metallopeptidase inhibitors TIMP-3 -1296 T>C (rs9619311) and TIMP-4 -55 T>C (rs3755724) were associated with the susceptibility of hepatocellular carcinoma among Taiwan women.

  16. Selective myocardial targeting for TIMP-4 induction through either a viral or transgenic approach favorably altered the course of adverse left ventricular remodeling post-myocardial infarction.

  17. The rs3755724 in TIMP4 protein was nominally associated with schizophrenia with poor concentration.

  18. Heterogeneous methylation in the promoter region of TIMP4 was associated with cancer progression in non-small cell lung cancer.

  19. A trend toward increased serum levels of MMP-9/TIMP-4 was found in patients with successful arteriovenous fistulas.

  20. Plasma TIMP-4 has a role in the prediction of LV remodeling and the pathophysiology of the heart postinfarction

Mouse (Murine) TIMP Metallopeptidase Inhibitor 4 (TIMP4) Interaktionspartner

  1. High TIMP4 expression is associated with obesity, fatty liver and dyslipidemia.

  2. there are 7 CpG islands in the TIMP4 promoter which get methylated during the progression of heart failure which leads to its epigenetic silencing.

  3. High fat diet-induced obesity downregulates adipocyte MMP3 expression to trigger adipogenesis, and adipocyte TIMP4 may modulate this process to regulate hyperplastic vs. hypertrophic adipose tissue expansion, fat distribution, and metabolic health in a sex- and depot-dependent manner.

  4. Our findings highlight a protective mechanism induced by PPARgamma in deoxycorticosterone acetate-salt treatment, establishing a novel mechanistic link between PPARgamma and TIMP-4.

  5. TIMP4 augments contractility and induces differentiation of embryonic stem cells into cardiac phenotype.

  6. TIMP-4 might act as a negative regulator of adipogenesis through NFkB cascade modulation.

  7. Replenishment of myocardial TIMP4 could serve as an effective therapy in post-I/R recovery for patients with reduced TIMP4.

  8. TIMP-4 protein was localized to corpus luteum and theca-intera cells in various periods throughout the pregnancy and postpartum day 1.

  9. Timp4(-/-) mice are more susceptible to MI but not to pressure overload, and TIMP4 functions in its capacity as a metalloproteinase inhibitor after myocardial infarction

  10. Identification of an initiator-like element essential for the expression of the tissue inhibitor of metalloproteinases-4 (Timp-4) gene

  11. molecular cloning and localization of the gene within intron 5 of the synapsin 2 gene

  12. This study suggests that tissue inhibitor of metalloproteinase-4 may restrict mouse blastocyst outgrowth and embryo implantation by inhibiting the activities of matrix metalloproteinases-2 and -9.

  13. Contractile responses of normal LV rings were measured in the presence and absence of CIMP. CIMP shifted the pressure-length relationship to the left, attenuated LV dilatation, and had no effect on CaCl2-mediated contraction [CIMP]

TIMP4 Protein Überblick

Protein Überblick

This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The secreted, netrin domain-containing protein encoded by this gene is involved in regulation of platelet aggregation and recruitment and may play role in hormonal regulation and endometrial tissue remodeling.

Genbezeichner und Symbole assoziert mit TIMP4

  • TIMP metallopeptidase inhibitor 4 (TIMP4)
  • TIMP metallopeptidase inhibitor 4, tandem duplicate 3 (timp4.3)
  • tissue inhibitor of metalloproteinase 4 (Timp4)
  • TIMP metallopeptidase inhibitor 4 (Timp4)
  • TIMP-4 Protein
  • timp4 Protein

Bezeichner auf Proteinebene für TIMP4

TIMP metallopeptidase inhibitor 4 , tissue inhibitor of metalloproteinase 4 , TIMP-4 , metalloproteinase inhibitor 4 , tissue inhibitor of metalloproteinases 4 , tissue inhibitor of metalloproteinase , tissue inhibitor of metalloproteinase-4 , TIMP2d

460176 Pan troglodytes
7079 Homo sapiens
317694 Bos taurus
100008691 Oryctolagus cuniculus
100124610 Danio rerio
110595 Mus musculus
680130 Rattus norvegicus
396774 Sus scrofa
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