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Synovial sarcomas occur most frequently in the extremities around large joints. Zusätzlich bieten wir Ihnen SS18L1 Antikörper (45) und viele weitere Produktgruppen zu diesem Protein an.
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calcium-responsive transactivator and certain other amyotrophic lateral sclerosis-linked proteins share several features implicated in amyotrophic lateral sclerosis pathogenesis
Its mutation causes amyotrophic lateral sclerosis.
This study demonistrated that CREST mutations inhibited activity-dependent neurite outgrowth in primary neurons, and CREST associated with the ALS protein FUS.
A synovial sarcoma of classic morphology contained a novel t(20;X) SS18L1(strong homology to SS18 on Ch20)/SSX1 fusion transcript in which nucleotide 1216 (exon 10) of SS18L1 was fused in-frame with nucleotide 422 (exon 6) of SSX1.
analysis of the CREST domain that inhibits dendritic growth in cultured neurons
SS18 and SS18L1 genes map within co-linear DNA segments that may have evolved through a relatively recent genomic duplication event.
Data suggest that co-activation of CREST and CBP (CREB-binding protein) enhances signaling between p-Creb/AP-1 and p-HIF-1/HRE resulting in up-regulation of Glut3 (glucose transporter type 3); here, stimulus was cell hypoxia.
Synovial sarcomas occur most frequently in the extremities around large joints. More than 90% of cases have a recurrent and specific chromosomal translocation, t(X\;18)(p11.2\;q11.2), in which the 5-prime end of the SS18 gene (MIM 600192) is fused in-frame to the 3-prime end of the SSX1 (MIM 312820), SSX2 (MIM 300192), or SSX4 (MIM 300326) gene. The SS18L1 gene is homologous to SS18.
synovial sarcoma translocation gene on chromosome 18-like 1
, SS18-like protein 1
, calcium-responsive transactivator
, ss18-like protein 1
, SYT homolog 1
, calcium-responsive transcription coactivator