anti-Sodium Channel, Voltage-Gated, Type XI, alpha Subunit (SCN11A) Antikörper

This protein mediates the voltage-dependent sodium ion permeability of excitable membranes.

Alle Antikörper anzeigen Gen GeneID UniProt
Anti-Maus SCN11A SCN11A 24046 Q9R053
Anti-Ratte SCN11A SCN11A 29701 O88457
Anti-Human SCN11A SCN11A 11280 Q9UI33
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Top anti-Sodium Channel, Voltage-Gated, Type XI, alpha Subunit Antikörper auf antikoerper-online.de

Showing 10 out of 21 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Maus Unkonjugiert ELISA, WB Detection limit for recombinant GST tagged SCN11A is approximately 0.03 ng/mL as a capture antibody. 0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$450.00
Details
Human Maus Unkonjugiert ELISA, WB Detection limit for recombinant GST tagged SCN11A is approximately 0.03ng/ml as a capture antibody. Western Blot detection against Immunogen (33 KDa) . 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
Details
Human Kaninchen Unkonjugiert IHC, WB   100 μL Anmelden zum Anzeigen 7 bis 8 Tage
$454.67
Details
Maus Kaninchen Unkonjugiert IHC   100 μL Anmelden zum Anzeigen 7 bis 8 Tage
$454.67
Details
Human Kaninchen Unkonjugiert IHC, IHC (p) Immunohistochemistry: SCN11A Antibody [NBP1-82600] - Staining of human rectum shows moderate cytoplasmic and membranous positivity in glandular cells. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details
Human Kaninchen Unkonjugiert IHC, WB   100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert IHC Immunohistochemistry: SCN11A Antibody [NBP2-48665] - Staining of human kidney shows strong cytoplasmic positivity in cells in tubules. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details
Human Kaninchen HRP ELISA   100 μg Anmelden zum Anzeigen 11 bis 18 Tage
$412.19
Details
Human Kaninchen FITC ELISA   100 μg Anmelden zum Anzeigen 11 bis 18 Tage
$412.19
Details
Human Kaninchen Biotin ELISA   100 μg Anmelden zum Anzeigen 11 bis 18 Tage
$412.19
Details

Weitere Antikörper gegen Sodium Channel, Voltage-Gated, Type XI, alpha Subunit Interaktionspartner

Mouse (Murine) Sodium Channel, Voltage-Gated, Type XI, alpha Subunit (SCN11A) Interaktionspartner

  1. This study demonstrated that NaV1.9 presumably contributes to acute thermal and mechanical nociception in mice.

  2. These results demonstrate that Nav1.9 channels play a critical role in the development of orofacial neuropathic pain.

  3. Recently Nav1.9, a voltage-gated sodium channel subtype, has been established as a genetic influence for certain peripheral pain syndromes.

  4. A missense mutation (p.V1184A) in NaV1.9 leads to cold-aggravated peripheral pain.

  5. We conclude that Nav1.9 acts as a subthreshold amplifier in cold-sensitive nociceptive neurons and is required for the perception of cold pain under normal and pathological conditions.

  6. NaV1.9 is required for persistence of responses to intense mechanical stimulation, contributes to inflammatory mechanical hypersensitivity, and is essential for activation by noxious inflammatory mediators, including those from diseased human bowel.

  7. The results strongly suggested that Nav1.9 was expressed and functionally contributed to the signaling processing in the central auditory pathway.

  8. Axon growth of NaV1.9-deficient motoneurons in cell culture is drastically reduce.

  9. In the stable NaV1.9-deficient cells we successfully constructed, proliferation, phagocytosis and migration were obviously inhibited.

  10. Na(V)1.9 function appears to be essential for activity-dependent axon growth in motor neurons, acting upstream of spontaneous Ca(2 (zeige CA2 Antikörper)+) elevation through voltage-gated calcium channels.

Human Sodium Channel, Voltage-Gated, Type XI, alpha Subunit (SCN11A) Interaktionspartner

  1. We identified a missense mutation of p.Arg225Cys in SCN11A in a four-generation Chinese family with early-onset familial episodic pain and adult onset familial essential tremor syndrome.

  2. SCN11A single-nucleotide polymorphisms affect Postoperative pain sensitivity in Chinese Han women after Gynecological surgery. The SNP rs33985936 and rs13080116 may serve as novel predictors for Postoperative pain.

  3. a U-shaped relationship between the resting potential and the neuronal action potential threshold explains why NaV1.9 mutations that evoke small degrees of membrane depolarization cause hyperexcitability and familial episodic pain disorder or painful neuropathy, while mutations evoking larger membrane depolarizations cause hypoexcitability and insensitivity to pain.

  4. Recently Nav1.9, a voltage-gated sodium channel subtype, has been established as a genetic influence for certain peripheral pain syndromes.

  5. Results show the expression of Nav1.9 channels within the human colon for the first time. Furthermore, Nav1.9 channel expression is decreased in Hirschsprung's disease versus normal controls.

  6. autosomal dominant Congenital insensitivity to pain reflects the second gain-of-function mutation of SCN11A.

  7. A missense mutation (p.V1184A) in NaV1.9 leads to cold-aggravated peripheral pain.

  8. A G699R substitution in the Nav1.9 domain II S4-S5 linker renders dorsal root ganglion neurons hyperexcitable, via depolarized resting membrane potential, reduced current threshold and increased evoked firing in small-fiber neuropathy.

  9. missense mutations of Nav1.9 in individuals with painful peripheral neuropathy

  10. The results demonstrate that Nav1.8 (zeige SCN10A Antikörper) and Nav1.9 are present in human lingual nerve neuromas, with significant correlations between the level of expression of Nav1.8 (zeige SCN10A Antikörper) and symptoms of pain.

Sodium Channel, Voltage-Gated, Type XI, alpha Subunit (SCN11A) Antigen-Profil

Protein Überblick

This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-resistant sodium channel isoform. Also involved, with the contribution of the receptor tyrosine kinase NTRK2, in rapid BDNF-evoked neuronal depolarization (By similarity).

Genbezeichner und Symbole assoziert mit SCN11A

  • sodium voltage-gated channel alpha subunit 11 (SCN11A) Antikörper
  • sodium channel protein type 11 subunit alpha (LOC100349709) Antikörper
  • sodium channel, voltage-gated, type XI, alpha (Scn11a) Antikörper
  • sodium voltage-gated channel alpha subunit 11 (Scn11a) Antikörper
  • NaN Antikörper
  • NaT Antikörper
  • NAV1.9 Antikörper
  • NSS2 Antikörper
  • SCN11A Antikörper
  • SCN12A Antikörper
  • SNS-2 Antikörper
  • SNS2 Antikörper

Bezeichner auf Proteinebene für SCN11A

sodium channel, voltage-gated, type XI, alpha subunit , sodium channel protein type 11 subunit alpha-like , sensory neuron sodium channel 2 , sodium channel protein type 11 subunit alpha , sodium channel protein type XI subunit alpha , sodium channel, voltage-gated, type XI, alpha polypeptide , voltage-gated sodium channel NAV1.9b , voltage-gated sodium channel subunit alpha Nav1.9 , sodium channel voltage-gated type 11 alpha polypeptide , sodium channel voltage-gated type XI alpha polypeptide , sodium channel, voltage-gated, type 11, alpha polypeptide , sodium channel, voltage-gated, type11, alpha polypeptide , PN5 , hNaN , peripheral nerve sodium channel 5 , sodium channel, voltage-gated, type XII, alpha polypeptide , voltage-gated sodium channel Nav1.9

GENE ID SPEZIES
460275 Pan troglodytes
100349709 Oryctolagus cuniculus
100414951 Callithrix jacchus
100464374 Ailuropoda melanoleuca
100601668 Nomascus leucogenys
24046 Mus musculus
29701 Rattus norvegicus
11280 Homo sapiens
485593 Canis lupus familiaris
100739142 Sus scrofa
535956 Bos taurus
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