anti-Sirtuin 7 (SIRT7) Antikörper

SIRT7 encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Zusätzlich bieten wir Ihnen Sirtuin 7 Kits (15) und Sirtuin 7 Proteine (15) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
SIRT7 51547 Q9NRC8
SIRT7 209011 Q8BKJ9
SIRT7 303745  
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Top anti-Sirtuin 7 Antikörper auf antikoerper-online.de

Showing 10 out of 173 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-SIRT7 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>SH-SYSY cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-SIRT7 Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>Jurkat cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert IHC (p), WB Anti- SIRT7 Picoband antibody, Western blotting All lanes: Anti SIRT7  at 0.5ug/ml Lane 1: Rat Spleen Tissue Lysate at 50ug Lane 2: Rat Brain Tissue Lysate at 50ug Lane 3: Rat Intestine Tissue Lysate at 50ug Lane 4: SMMC Whole Cell Lysate at 40ug Lane 5: JURKAT Whole Cell Lysate at 40ug Predicted bind size: 45KD Observed bind size: 45KD Anti- SIRT7 Picoband antibody, IHC(P) IHC(P): Mouse Spleen Tissue 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$280.00
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of SIRT7 (arrow) using SIRT7 Antibody (C-term) (ABIN390182). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the SIRT7 gene (Lane 2). Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert WB Western Blot: SIRT7 Antibody [ABIN43538884] - Analysis of SIRT7 in A) human liver and B) PBMC lysate using this antibody at 1 ug/ml. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$345.00
Details
Human Kaninchen Unkonjugiert IF, IP, WB SIRT7 MaxPab rabbit polyclonal antibody. Western Blot analysis of SIRT7 expression in human liver. SIRT7 MaxPab rabbit polyclonal antibody. Western Blot analysis of SIRT7 expression in mouse liver. 100 μL Anmelden zum Anzeigen 11 bis 12 Tage
$425.71
Details
Human Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$205.00
Details
Human Kaninchen Unkonjugiert ICC, IF, IP SIRT7 Immunoprecipitated from human liver lysates with ABIN259767. A). ABIN259751 B). ABIN259749 Immunocytochemistry/Immunofluorescence: SIRT7 Antibody [ABIN2597682] - SIRT7 antibody was tested in U2OS cells with DyLight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red). 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$444.19
Details
Human Kaninchen Unkonjugiert ICC, IF, WB Detection of SIRT7 in human liver lysates using ABIN259749. SIRT7 Immunoprecipitated from human liver lysates with ABIN259767. A). ABIN259751 B). ABIN259749 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$444.19
Details
Rind (Kuh) Kaninchen Unkonjugiert ICC, IF, WB Detection of SIRT7 in human liver lysates using ABIN259751. SIRT7 Immunoprecipitated from human liver lysates with ABIN259767. A). ABIN259751 B). ABIN259749 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$444.19
Details

SIRT7 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Sirtuin 7 Antikörper

  1. Human Polyclonal SIRT7 Primary Antibody für IHC (p), WB - ABIN390182 : Wang, Yi, Li, Cai, He, Ni, Zhou, Cheng, Jin, Fan, Qiu: Down-regulation of sirtuin 3 is associated with poor prognosis in hepatocellular carcinoma after resection. in BMC cancer 2014 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal SIRT7 Primary Antibody für IF, IP - ABIN950083 : Lim, Barker, Menon, Lappas: A Novel Role for SIRT3 in Regulating Mediators Involved in the Terminal Pathways of Human Labor and Delivery. in Biology of reproduction 2016 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal SIRT7 Primary Antibody für IHC (fro), IF (p) - ABIN760571 : Takumida, Takumida, Anniko: Localization of sirtuins in the mouse inner ear. in Acta oto-laryngologica 2014 (PubMed)
    Show all 2 Pubmed References

  4. Human Polyclonal SIRT7 Primary Antibody für ICC, IF - ABIN259767 : Zhang, Li, Deng, Liu, Chen, Tang, Wang, Cao, Fang, Wen, Xu, Chen, Shi, Li, Xie, Tang: Dicer interacts with SIRT7 and regulates H3K18 deacetylation in response to DNA damaging agents. in Nucleic acids research 2016 (PubMed)

  5. Polyclonal SIRT7 Primary Antibody für IP, WB - ABIN540297 : Frye: Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins. in Biochemical and biophysical research communications 2000 (PubMed)

  6. Human Polyclonal SIRT7 Primary Antibody für WB - ABIN4353888 : Alhazzazi, Kamarajan, Joo, Huang, Verdin, DSilva, Kapila: Sirtuin-3 (SIRT3), a novel potential therapeutic target for oral cancer. in Cancer 2011 (PubMed)

Weitere Antikörper gegen Sirtuin 7 Interaktionspartner

Human Sirtuin 7 (SIRT7) Interaktionspartner

  1. Authors evaluated the expression of known targets of miR (zeige MLXIP Antikörper)-125a and found that sirtuin-7, matrix metalloproteinase-11 (zeige MMP11 Antikörper), and c-Raf (zeige RAF1 Antikörper) were up-regulated in tumor tissue by 2.2-, 3-, and 1.7-fold, respectively. Overall, these data support a tumor suppressor role for miR (zeige MLXIP Antikörper)-125a.

  2. We found a negative correlation between mRNA levels of SIRT1 (zeige SIRT1 Antikörper) in VAT of obese individuals and SIRT7 in VAT of the normal-weight subjects and expression of the relevant miRNAs.

  3. Data indicate the role of SIRT7 in inhibiting SMAD4 (zeige SMAD4 Antikörper)-mediated breast cancer metastasis providing a possible therapeutic avenue.

  4. Energy stress strengthens SIRT7-mediated effects on Akt (zeige AKT1 Antikörper) dephosphorylation.

  5. The SIRT7 is mobilized from the nucleolus to the nucleoplasm and promotes DDB1 deacetylation, leading to decreased DDB1-CUL4 association and CRL4 activity.

  6. Data suggest that SIRT7 undergoes Lys (zeige LYZ Antikörper)-63 polyubiquitination, later removed by USP7 (zeige USP7 Antikörper) to repress enzymatic activity of SIRT7; USP7 (zeige USP7 Antikörper) and SIRT7 regulate gluconeogenesis via expression of glucose-6-phosphatase catalytic subunit (G6PC (zeige G6PC Antikörper)); SIRT7 targets G6PC (zeige G6PC Antikörper) promoter through ELK4 (zeige ELK4 Antikörper). (SIRT7 = sirtuin 7; USP7 (zeige USP7 Antikörper) = ubiquitin specific peptidase 7 (zeige USP7 Antikörper); G6PC (zeige G6PC Antikörper) = glucose-6-phosphatase catalytic subunit (zeige G6PC Antikörper); ELK4 (zeige ELK4 Antikörper) = transcription factor ELK4 (zeige ELK4 Antikörper))

  7. the decline in SIRT7 in lung fibroblasts has a profibrotic effect, which is mediated by changes in Smad3 (zeige SMAD3 Antikörper) levels.

  8. SIRT7 inhibits TR4 degradation by deacetylation of DDB1.

  9. miR (zeige MLXIP Antikörper)-152/SIRT7 axis plays a key role in the regulation of Human dental pulp stem cell senescence.

  10. our study suggests that SIRT7 functions as an oncogene (zeige RAB1A Antikörper) in non-small cell lung cancer (NSCLC), and miR (zeige MLXIP Antikörper)-3666 can target SIRT7 to inhibit NSCLC cell growth by promoting the pro-apoptotic signaling pathway

Mouse (Murine) Sirtuin 7 (SIRT7) Interaktionspartner

  1. the results of our study suggest that SIRT7 is involved in protecting neurons against OGD (zeige FGFR1 Antikörper)/R-induced injury, possibly through regulation of the p53 (zeige TP53 Antikörper)-mediated proapoptotic signaling pathway, indicating a potential therapeutic target for cerebral ischemia/reperfusion injury.

  2. Histological analysis revealed that there is no apparent structural abnormality of the amygdala and hippocampus, which are regions involved in fear memory consolidation, in Sirt7 KO mice. Our results indicate that SIRT7 is involved in the consolidation of fear memory.

  3. Data suggest that high-fat diet (HFD) alters regulation of expression of sirtuins (Sirt4 (zeige SIRT4 Antikörper) and Sirt7) and enzymes in NAD biosynthetic pathway (Tdo2 (zeige TDO2 Antikörper) and Nnmt (zeige NNMT Antikörper)); these alterations are more prominent in liver as compared to white adipose tissue or skeletal muscle; Tdo2 (zeige TDO2 Antikörper) and Nnmt (zeige NNMT Antikörper) may serve as markers of HFD consumption. (Tdo2 (zeige TDO2 Antikörper) = tryptophan 2,3-dioxygenase (zeige TDO2 Antikörper); Nnmt (zeige NNMT Antikörper) = nicotinamide N-methyltransferase (zeige NNMT Antikörper))

  4. The Sirt7 mediates heterochromatin formation at rRNA genes through recruitment of DNA methyltransferase 1 (zeige DNMT1 Antikörper) and another member of the sirtuin (zeige SIRT1 Antikörper) family, Sirt1 (zeige SIRT1 Antikörper).

  5. the decline in SIRT7 in lung fibroblasts has a profibrotic effect, which is mediated by changes in Smad3 (zeige SMAD3 Antikörper) levels.

  6. SIRT7 inhibits TR4 degradation by deacetylation of DDB1.

  7. These results reveal a direct role for SIRT7 in double-strand break repair and establish a functional link between SIRT7-mediated histone H3 (zeige HIST3H3 Antikörper) K18 (zeige KRT18 Antikörper) deacetylation and the maintenance of genome integrity.

  8. miR (zeige MLXIP Antikörper)-93 inhibits the metabolic target Sirt7, which we identified as a major driver of in vivo adipogenesis via induction of differentiation and maturation of early adipocyte precursors.

  9. The role of SIRT7 has emerged in protein synthesis, chromatin remodelling, cellular survival and lipid metabolism.

  10. SIRT7 stabilizes and activates the GABP alpha (zeige GABPA Antikörper)/GABPbeta complex via deacetylation of GABPbeta1.

Sirtuin 7 (SIRT7) Antigen-Profil

Protein Überblick

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined\; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.

Genbezeichner und Symbole assoziert mit anti-Sirtuin 7 (SIRT7) Antikörper

  • sirtuin 7 (SIRT7) Antikörper
  • sirtuin 7 (sirt7) Antikörper
  • phosphate cytidylyltransferase 2, ethanolamine (PCYT2) Antikörper
  • sirtuin 7 (Sirt7) Antikörper
  • LOC796135 Antikörper
  • SIR2L7 Antikörper
  • SIRT7 Antikörper

Bezeichner auf Proteinebene für anti-Sirtuin 7 (SIRT7) Antikörper

sirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae) , sirtuin 7 , novel protein similar to vertebratesirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae) (SIRT7) , NAD-dependent deacetylase sirtuin-7 , sirtuin , NAD-dependent protein deacetylase sirtuin-7 , SIR2-like protein 7 , regulatory protein SIR2 homolog 7 , silent mating type information regulation 2, S.cerevisiae, homolog 7 , sir2-related protein type 7 , sirtuin type 7 , NAD-dependent deacetylase sirtuin 7

GENE ID SPEZIES
454975 Pan troglodytes
796135 Danio rerio
422093 Gallus gallus
51547 Homo sapiens
209011 Mus musculus
303745 Rattus norvegicus
483371 Canis lupus familiaris
100125965 Sus scrofa
505662 Bos taurus
Ausgewählte Anbieter für anti-Sirtuin 7 (SIRT7) Antikörper
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