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SRP68 encodes a subunit of the signal recognition particle (SRP). Zusätzlich bieten wir Ihnen SRP68 Antikörper (22) und viele weitere Produktgruppen zu diesem Protein an.
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This multicenter data analysis establishes a six-genotype genetic prognostic model for poor outcomes of papillary thyroid cancer with a risk order of genetic duet of BRAF V600E/RAS mutation and TERT mutation >>>>BRAF V600E = TERT mutation alone >RAS mutation alone = wild-type genes.
Despite a significant prevalence of BRAF (zeige BRAF Proteine) mutation, more than 70% of hobnail variant of papillary thyroid carcinomas (HPTCs) in our series showed concurrent mutations of other genes such as TP53 (zeige TP53 Proteine), PIK3CA (zeige PIK3CA Proteine), CTNNB1 (zeige CTNNB1 Proteine) and hTERT, in contrast to classic PTC (zeige F9 Proteine).
Mutational activation of BRAF (zeige BRAF Proteine) confers sensitivity to TGFBR1 (zeige TGFBR1 Proteine) inhibitors in human melanoma cells.
miR (zeige MLXIP Proteine)-579-3p controls melanoma progression and resistance to target therapy by targeting the 3'UTR of two oncoproteins: BRAF (zeige BRAF Proteine) and MDM2 (zeige MDM2 Proteine).
Durable (>/=3 years) survival is achievable with dabrafenib plus trametinib in patients with BRAF (zeige BRAF Proteine) V600-mutant metastatic melanoma
A high extent more than 25% of BRAF (zeige BRAF Proteine)(V600E) alleles may be associated with disease outcome in PTC (zeige F9 Proteine) patients.
Study found that high expression of LC3B (zeige MAP1LC3B Proteine) protein was associated with the presence of BRAF (zeige BRAF Proteine) V600E mutation and temporal lesion in glioneuronal tumors, as well as in gangliogliomas alone. As for Beclin-1 protein (zeige BECN1 Proteine), it showed statistically significant correlation with BRAF (zeige BRAF Proteine) V600E mutation in glioneuronal tumors.
We suggest that BRAF (zeige BRAF Proteine) mutant patients should not be considered as having a unique biology and provide an in depth characterization of heterogeneous motifs that may be exploited for drug targeting.
The results establish a link between BRAF (zeige BRAF Proteine)(V600E) and NOX4 (zeige NOX4 Proteine), which is confirmed by a comparative analysis of NOX4 (zeige NOX4 Proteine) expression in human (TCGA) and mouse thyroid cancers.
PD-L1 (zeige CD274 Proteine) expression in colorectal cancer is associated with microsatellite instability and BRAF (zeige BRAF Proteine) mutations.
This gene encodes a subunit of the signal recognition particle (SRP). The SRP is a ribonucleoprotein complex that transports secreted and membrane proteins to the endoplasmic reticulum for processing. The complex includes a 7S RNA and six protein subunits. The encoded protein is the 68kDa component of the SRP, and forms a heterodimer with the 72kDa subunit that is required for SRP function. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and three pseudogenes of this gene are located within the Smith-Magenis syndrome region on chromosome 17.
94 kDa B-raf protein
, B-Raf proto-oncogene serine/threonine-protein kinase (p94)
, murine sarcoma viral (v-raf) oncogene homolog B1
, proto-oncogene B-Raf
, serine/threonine-protein kinase B-raf
, v-raf murine sarcoma viral oncogene homolog B1
, Signal recognition particle 68kDa
, signal recognition particle 68kDa
, likely ortholog of H. sapiens signal recognition particle 68kDa (SRP68)
, signal recognition particle 68 kDa protein
, signal recognition particle subunit SRP68
, signal recognition particle protein 68
, 68kDA subunit of signal recognition particle
, Signal recognition particle 68 kDa protein