Secreted Phosphoprotein 2 Proteine (SPP2)

SPP2 encodes a secreted phosphoprotein that is a member of the cystatin superfamily. Zusätzlich bieten wir Ihnen SPP2 Kits (19) und SPP2 Antikörper (18) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
SPP2 75396 Q8K1I3
Ratte SPP2 SPP2 94168 Q62740
SPP2 6694 Q13103
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Top SPP2 Proteine auf antikoerper-online.de

Showing 6 out of 6 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$5,465.26
Details
Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$5,465.26
Details
Hefe Huhn His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,370.50
Details
Hefe Regenbogenforelle His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,405.33
Details
Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,423.67
Details
Escherichia coli (E. coli) Human T7 tag,His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$733.00
Details

SPP2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine)

Human
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Weitere Proteine zu Secreted Phosphoprotein 2 (SPP2) Interaktionspartnern

Mouse (Murine) Secreted Phosphoprotein 2 (SPP2) Interaktionspartner

  1. proteolytic processing of spp24 affects the interaction of this protein with BMP-2 (zeige BMP2 Proteine) and this affects the function of the protein

Human Secreted Phosphoprotein 2 (SPP2) Interaktionspartner

  1. Spp24 can inhibit the growth of prostate cancer and its bone metastasis induced by BMP2 (zeige BMP2 Proteine); spp24 may have great potential to be a therapeutic agent in clinical situations

  2. the two mutations of SPP2 have dominant negative effects and cellular accumulation of Spp-24 might be particularly toxic to photoreceptors and/or retinal pigment epithelium. SPP2 has a new role in retinal degeneration.

  3. Report describes a C-terminal fragment within SPP24 that is distinct from the cystatin (zeige CST3 Proteine) domain and which independently binds to BMP-2 (zeige BMP2 Proteine) and TGF-beta (zeige TGFB1 Proteine). This fragment inhibited BMP-2 (zeige BMP2 Proteine) activity in an ectopic bone forming assay.

  4. Spp24, or proteolytic products of Spp24, bind cytokines of the TGF-beta (zeige TGFB1 Proteine) superfamily and also activate intracellular signaling pathways [review]

  5. Spp24 truncation products have effects on osteoblastic differentiation mediated by kinase pathways that are independent of exogenous BMP/TGF-beta (zeige TGFb Proteine) cytokines.

  6. Results describe the localization of the human secreted phosphoprotein 24 gene, its structure and the start of transcription in liver.

  7. spp24 contains at least 2 single nucleotide polymorphisms. Given its mechanism of action and sequence variability, SPP24 may be an interesting candidate for future studies of the genetic regulation of bone mass.

Cow (Bovine) Secreted Phosphoprotein 2 (SPP2) Interaktionspartner

  1. We report here for the first time the direct isolation of Spp24 covalently bound to alpha2-macroglobulins as a core complex (Spp24-alpha2M) from bovine calf serum.

  2. The beta-pleated sheets of recombinant spp24 play a greater role in bone morphogenetic protein (BMP)-2 binding than does the alpha-helical turn.

  3. levels of spp24 in bone may be regulated, in part, by calcium-dependent proteolysis mediated by osteoblastic cells

SPP2 Protein Überblick

Protein Überblick

This gene encodes a secreted phosphoprotein that is a member of the cystatin superfamily.

Genbezeichner und Symbole assoziert mit SPP2

  • secreted phosphoprotein 2 (spp2)
  • secreted phosphoprotein 2 (Spp2)
  • secreted phosphoprotein 2 (SPP2)
  • 0610038O04Rik Protein
  • GHRG-1 Protein
  • pp-24 Protein
  • SPP-24 Protein
  • SPP24 Protein

Bezeichner auf Proteinebene für SPP2

secreted phosphoprotein 24 , spp-24 , secreted phosphoprotein 2 , secreted phosphoprotein 2, 24kDa , growth hormone regulated gene-1

GENE ID SPEZIES
100136400 Salmo salar
75396 Mus musculus
94168 Rattus norvegicus
6694 Homo sapiens
281500 Bos taurus
396080 Gallus gallus
396669 Sus scrofa
443510 Ovis aries
100136098 Oncorhynchus mykiss
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