anti-Rotatin (RTTN) Antikörper

RTTN encodes a large protein whose specific function is unknown. Zusätzlich bieten wir Ihnen Rotatin Kits (1) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
RTTN 25914 Q86VV8
Anti-Maus RTTN RTTN 246102 Q8R4Y8
Anti-Ratte RTTN RTTN 291377  
Direkt bei antikoerper-online bestellen
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Online bestellen

Top anti-Rotatin Antikörper auf

Showing 3 out of 4 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IHC (p) Immunohistochemical staining of human stomach with RTTN polyclonal antibody  shows strong cytoplasmic positivity in gastric parietal cells at 1:200-1:500 dilution. 100 μL Anmelden zum Anzeigen 11 bis 12 Tage
Human Kaninchen Unkonjugiert IHC, IHC (p) Immunohistochemistry: rotatin Antibody [NBP1-90554] - Staining of human stomach, lower shows strong cytoplasmic positivity in gastric parietal cells. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p) Immunohistochemistry-Paraffin: rotatin Antibody [NBP1-90555] - Staining of human stomach, lower shows moderate cytoplasmic positivity in glandular cells. Immunocytochemistry/Immunofluorescence: rotatin Antibody [NBP1-90555] - Staining of human cell line A-431 shows positivity in mitochondria. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage

Weitere Antikörper gegen Rotatin Interaktionspartner

Human Rotatin (RTTN) Interaktionspartner

  1. We here report three individuals from two unrelated families with novel mutations in the RTTN gene. The phenotype consisted of microcephaly, short stature, pachygyria or polymicrogyria, colpocephaly, hypoplasia of the corpus callosum and superior vermis. These findings provide further confirmation of the phenotype related to pathogenic variants in RTTN.

  2. We identified, by trio based whole exome sequencing, a homozygous missense mutation in the RTTN gene (c.2953A>G; p.(Arg985Gly)) in one Moroccan patient from a consanguineous family.

  3. Data show that PPP1R35 acts downstream of, and forms a complex with, RTTN, a microcephaly protein required for distal centriole elongation.

  4. RTTN directly interacts with STIL and acts downstream of STIL-mediated centriole assembly, contributing to building full-length centrioles.

  5. We found a novel homozygous mutation in RTTN associated with microcephalic PD as well as complex brain malformations and congenital dermatitis, thus expanding the phenotypic spectrum of both RTTN-associated diseases and ciliary dysfunction.

  6. RTTN mutations cause primary microcephaly and primordial dwarfism in humans.

  7. RTTN mutations therefore link aberrant ciliary function to abnormal development and organization of the cortex in human individuals.

  8. Study characterizing mouse rotatin gene.

Mouse (Murine) Rotatin (RTTN) Interaktionspartner

  1. cloning and characterization of rotatin

  2. No turning (nt), a recessive lethal mutation causing left-right and axial patterning defects is likely elicited by deficiency of Rttn on chromosome 18.

Rotatin (RTTN) Antigen-Profil

Protein Überblick

This gene encodes a large protein whose specific function is unknown. Absence of the orthologous protein in mouse results in embryonic lethality with deficient axial rotation, abnormal differentiation of the neural tube, and randomized looping of the heart tube during development. In human, mutations in this gene are associated with polymicrogyria with seizures. In human fibroblasts this protein localizes at the ciliary basal bodies. Given the intracellular localization of this protein and the phenotypic effects of mutations, this gene is suspected of playing a role in the maintenance of normal ciliary structure which in turn effects the developmental process of left-right organ specification, axial rotation, and perhaps notochord development.

Genbezeichner und Symbole assoziert mit anti-Rotatin (RTTN) Antikörper

  • rotatin (RTTN) Antikörper
  • rotatin (Rttn) Antikörper
  • rotatin (LOC100074695) Antikörper
  • rotatin (rttn) Antikörper
  • rotatin (LOC100542421) Antikörper
  • 4921538A15Rik Antikörper
  • AI666264 Antikörper
  • C530033I08Rik Antikörper
  • D230040K24 Antikörper

Bezeichner auf Proteinebene für anti-Rotatin (RTTN) Antikörper


25914 Homo sapiens
246102 Mus musculus
291377 Rattus norvegicus
421023 Gallus gallus
455466 Pan troglodytes
483940 Canis lupus familiaris
615378 Bos taurus
703989 Macaca mulatta
100020422 Monodelphis domestica
100052029 Equus caballus
100074695 Ornithorhynchus anatinus
100151439 Danio rerio
100302015 Oryzias latipes
100343652 Oryctolagus cuniculus
100379860 Xenopus (Silurana) tropicalis
100452537 Pongo abelii
100474442 Ailuropoda melanoleuca
100542421 Meleagris gallopavo
100623296 Sus scrofa
Ausgewählte Anbieter für anti-Rotatin (RTTN) Antikörper
Haben Sie etwas anderes gesucht?