Reticulocalbin 1, EF-Hand Calcium Binding Domain Proteine (RCN1)

Mouse (Murine) Reticulocalbin 1, EF-Hand Calcium Binding Domain (RCN1) Interaktionspartner

1. In the adult mice, RCAN1 (zeige RCAN1 Proteine) was mainly expressed in the neuropil throughout the brain.

Human Reticulocalbin 1, EF-Hand Calcium Binding Domain (RCN1) Interaktionspartner

1. RCN1 (zeige RCAN1 Proteine) may promote cell survival and serve as a useful target for cancer therapy.

2. irradiated tumor cells were observed to significantly up-regulate the expression of calcium-binding proteins CALM1, CALU (zeige CALU Proteine), and RCN1 (zeige RCAN1 Proteine), suggesting important roles for these mediators in promoting tumor cell survival during hypoxia

3. RCN1 (zeige RCAN1 Proteine) expression was not statistically significantly different to healthy controls but was associated with disease activity score and could be used as a stratification biomarker for systemic sclerosis patients.

4. reticulocalbin-1 plays a key role in the development of doxorubicin-associated resistance

5. Ca(2 (zeige CA2 Proteine)+) binding caused an increase in the alpha-helix content of human RCN1 (zeige RCAN1 Proteine). On the other hand, RCN1 (zeige RCAN1 Proteine) did not change the structure with Mg.

6. a promising role of RCN1 (zeige RCAN1 Proteine) as a possible marker in Renal cell carcinoma (zeige MOK Proteine)

7. reticulocalbin-1 may be an important molecule in understanding lymphatic endothelial cells in tumors function and control of lymphatic metastasis.

8. Increased RCN1 (zeige RCAN1 Proteine) is associated with systemic sclerosis and nephrogenic systemic fibrosis.

9. deletion of Rcn1 (zeige RCAN1 Proteine) directly or indirectly contributes to the eye phenotype in Pax6 (zeige PAX6 Proteine) contiguous gene deletions

10. RCN1 (zeige RCAN1 Proteine) also is expressed on the cell surface of several endothelial cell lines, including human dermal microvascular endothelial cells (HDMVECs), bone marrow endothelial cells (BMEC), and transformed human bone marrow endothelial cells (TrHBMEC).