anti-Rac GTPase Activating Protein 1 (RACGAP1) Antikörper

The protein encoded by RACGAP1 belongs to the GTPase-activating protein (GAP) family. Zusätzlich bieten wir Ihnen RACGAP1 Kits (22) und RACGAP1 Proteine (7) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
RACGAP1 29127 Q9H0H5
RACGAP1 26934 Q9WVM1
RACGAP1 315298  
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Top anti-RACGAP1 Antikörper auf

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Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-RACGAP1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>ACHN cell lysate WB Suggested Anti-RACGAP1 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500 <br /> Positive Control: ACHN cell lysate <br /> RACGAP1 is supported by BioGPS gene expression data to be expressed in ACHN 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
Rind (Kuh) Kaninchen Unkonjugiert WB Host: Rabbit <br /> Target Name: Racgap1 <br /> Sample Tissue: Rat Stomach lysates <br /> Antibody Dilution: 1.0 µg/mL 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
Human Ziege Unkonjugiert IHC, ELISA, WB ABIN184690 staining (0.2µg/ml) of Human Testis lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. ABIN184690 (1µg/ml) staining of paraffin embedded Human Testis. Microwaved antigen retrieval with Tris/EDTA buffer pH9, HRP-staining. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
Human Kaninchen Unkonjugiert EIA, FACS, IF, IHC (p), WB Flow Cytometric analysis of MCF-7 cells using RACGAP1 Antibody (N-term) Cat.-No AP53556PU-N (right histogram) compared to a Negative Control cell (left histogram). FITC-conjugated Goat-anti-Rabbit secondary antibodies were used for the analysis. Confocal immunofluorescent analysis of RACGAP1 Antibody (N-term) Cat.-No AP53556PU-N with MCF-7 cell followed by Alexa Fluor 488-conjugated Goat anti-Rabbit lgG (green).DAPI was used to stain the cell nuclear (blue). 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
Human Kaninchen Unkonjugiert IC, IF, IHC, WB Immunofluorescent analysis of MGCRACGAP staining in K562 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of MGCRACGAP staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
Human Maus Unkonjugiert WB RACGAP1 monoclonal antibody (M01), clone 1G6. Western Blot analysis of RACGAP1 expression in Jurkat. 0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
Human Kaninchen Unkonjugiert ICC, IF, IHC (p), IHC, WB Immunohistochemistry-Paraffin: MgcRacGAP/RACGAP1 Antibody [NBP1-33455] - Paraffin-embedded H1299 xenograft. Immunohistochemistry-Paraffin: MgcRacGAP/RACGAP1 Antibody [NBP1-33455] - Paraffin-embedded Hepatoma. 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
Human Kaninchen Unkonjugiert IF, IHC, WB 100 μL Anmelden zum Anzeigen 16 Days
Human Kaninchen Unkonjugiert FACS, IF, IHC (p), WB Confocal immunofluorescent analysis of RACGAP1 Antibody (N-term)(ABIN655408) with MCF-7 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
Human Maus Unkonjugiert ELISA, WB Immunoperoxidase of monoclonal antibody to RACGAP1 on formalin-fixed paraffin-embedded human testis. [antibody concentration 1 ug/ml] Detection limit for recombinant GST tagged RACGAP1 is approximately 0.3ng/ml as a capture antibody. 100 μg Anmelden zum Anzeigen 11 bis 12 Tage

RACGAP1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-RACGAP1 Antikörper

  1. Human Monoclonal RACGAP1 Primary Antibody für ELISA, WB - ABIN565414 : Wolfe, Takaki, Petronczki, Glotzer: Polo-like kinase 1 directs assembly of the HsCyk-4 RhoGAP/Ect2 RhoGEF complex to initiate cleavage furrow formation. in PLoS biology 2009 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal RACGAP1 Primary Antibody für IHC (p), IHC - ABIN257840 : Reibel, Dorseuil, Stancou, Bertoglio, Gacon: A hemopoietic specific gene encoding a small GTP binding protein is overexpressed during T cell activation. in Biochemical and biophysical research communications 1991 (PubMed)

Weitere Antikörper gegen RACGAP1 Interaktionspartner

Xenopus laevis Rac GTPase Activating Protein 1 (RACGAP1) Interaktionspartner

  1. MgcRacGAP SxIP motif is functionally important both for its role in regulating adherens junction structure during interphase and for regulating Rho GTPase activity during cytokinesis.

Human Rac GTPase Activating Protein 1 (RACGAP1) Interaktionspartner

  1. Study showed that a subset of epithelial ovarian cancer (EOC) patients have RacGAP1 overexpression which is associated with advanced tumor stages and poor clinical outcomes. Also, RacGAP1 can positively regulate the activation of RhoA (zeige RHOA Antikörper) and Erk (zeige EPHB2 Antikörper) proteins, thus up-enhance the migration and invasion process of EOC.

  2. Data show that comparing with Ki-67 (zeige MKI67 Antikörper) and TOP2A (zeige TOP2A Antikörper), RacGAP1 allowed for a clearer prognostic statement.

  3. RACGAP1 promotes the metastatic phenotype in uterine carcinosarcoma via a STAT3 (zeige STAT3 Antikörper)/survivin (zeige BIRC5 Antikörper) signaling pathway.

  4. High RACGAP1 expression is associated with Basal-like Breast Cancers.

  5. Data suggest that MGCRABGAP (zeige TBC1D21 Antikörper) is involved in mammalian spermiogenesis by modulating RAB10 (zeige RAB10 Antikörper).

  6. This study showed that the overexpressions of Ki67 (zeige MKI67 Antikörper), RacGAP1, and TOP2a (zeige TOP2A Antikörper) affect the prognosis of female breast cancer patients adversely

  7. Data confirmed a strong correlation of AURKA (zeige AURKA Antikörper) and Wnt (zeige WNT2 Antikörper)-modulator RACGAP1 gene expression both in the gastric tumor, the tumor-adjacent and the tumor-distant mucosa.

  8. RacGAP1 Is a Novel Downstream Effector of E2F7 (zeige E2F7 Antikörper)-Dependent Resistance to Doxorubicin and Is Prognostic for Overall Survival in Squamous Cell Carcinoma

  9. RACGAP1 expression levels in the nucleus and cytoplasm, determined by immunohistochemical staining, predict opposite clinical outcomes and that both could be independent prognostic markers for colorectal cancer.

  10. central spindle assembly and 2 Plk1 (zeige PLK1 Antikörper)-dependent phosphorylations are required to establish efficient binding of the Ect2 (zeige ECT2 Antikörper) BRCT in early cytokinesis.

Mouse (Murine) Rac GTPase Activating Protein 1 (RACGAP1) Interaktionspartner

  1. Deletion of MgcRacGAP in the male germ cells impairs spermatogenesis and causes male sterility in the mouse.

  2. APC (zeige APC Antikörper)(CDH1 (zeige CDH1 Antikörper)) targets MgcRacGAP for destruction in the late M phase.

  3. TLR4 (zeige TLR4 Antikörper) signaling shapes B cell dynamics via MyD88 (zeige MYD88 Antikörper)-dependent pathways and Rac (zeige AKT1 Antikörper) GTPases.

  4. several Rho family small GTPases activate PI3K by an indirect cooperative positive feedback that required a combination of Rac (zeige AKT1 Antikörper), CDC42 (zeige CDC42 Antikörper), and RhoG small GTPase activities

  5. Rac regulates vascular endothelial growth factor stimulated motility

  6. These results indicate that MgcRacGAP regulates cytokinesis and cellular differentiation as a regulator of Rho family of GTPase and suggest that this process is controlled by some serine/threonine kinases.

  7. alpha5 is required for proliferation and polarity of basal epithelial cells; the interaction between laminin-10/11-integrin alpha6beta4 and the PI3-kinase (zeige PIK3CA Antikörper)-Cdc42 (zeige CDC42 Antikörper)/Rac (zeige AKT1 Antikörper) pathways may play a role in determining the size and shape of tooth germ

  8. Gab2 (zeige GAB2 Antikörper) via Shp-2 (zeige PTPN11 Antikörper) is critical for transmitting signals from Kit Tyr (zeige TYR Antikörper)(567) to activate the Rac (zeige AKT1 Antikörper)/JNK (zeige MAPK8 Antikörper) pathway controlling mast cell proliferation

  9. Data demonstrate that normal cytokinesis in B lymphocytes requires the GAP and NH2 terminal domains but not GAP activity of mgcRacGAP.

  10. Rac (zeige AKT1 Antikörper) became activated within 2 min after peripheral membrane extensions adhered to new ECM (zeige MMRN1 Antikörper) islands, and this activation wave propagated outward in an oriented manner as the cells spread from island to island

Zebrafish Rac GTPase Activating Protein 1 (RACGAP1) Interaktionspartner

  1. In vivo cell recordings reveal that gradual loss of wild-type RacGAP1 leads progressively from a failure of abscission, then to cleavage furrow ingression, and finally complete absence of furrow formation. Despite the lack of cytokinesis, gross patterning occurs overtly normally in ogre mutants and cells continue to cycle slowly, some even attaining four or eight nuclei.

RACGAP1 Antigen-Profil

Protein Überblick

The protein encoded by this gene belongs to the GTPase-activating protein (GAP) family. GAPs bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, GAPs negatively regulate Rho-mediated signals. This protein plays a regulatory role in initiation of cytokinesis, controlling cell growth and differentiation of hematopoietic cells, regulating spermatogenesis, and in neuronal proliferation. Alternatively spliced transcript variants have been found for this gene.

Genbezeichner und Symbole assoziert mit RACGAP1

  • Rac GTPase activating protein 1 (racgap1) Antikörper
  • Rac GTPase activating protein 1 L homeolog (racgap1.2.L) Antikörper
  • Rac GTPase activating protein 1 (RACGAP1) Antikörper
  • Rac GTPase activating protein 1 (racgap1.2) Antikörper
  • Rac GTPase activating protein 1 L homeolog (racgap1.L) Antikörper
  • rac GTPase-activating protein 1 (RACGAP1) Antikörper
  • Rac GTPase activating protein 1 (Racgap1) Antikörper
  • Rac GTPase-activating protein 1 (Racgap1) Antikörper
  • AI227039 Antikörper
  • AI327394 Antikörper
  • Band25 Antikörper
  • cyk-4 Antikörper
  • CYK4 Antikörper
  • gtl11 Antikörper
  • GTPase Antikörper
  • HsCYK-4 Antikörper
  • ID-GAP Antikörper
  • MGC121578 Antikörper
  • MgcRacGAP Antikörper
  • mKIAA1478 Antikörper
  • RACGAP1 Antikörper
  • wu:fb92c08 Antikörper
  • zgc:77839 Antikörper

Bezeichner auf Proteinebene für RACGAP1

Rac GTPase activating protein 1 , rac GTPase-activating protein 1-like , GTPase activating protein , male germ cell RacGap , protein CYK4 homolg , protein CYK4 homolog , rac GTPase-activating protein 1 , Rac GTPase-activating protein 1

407917 Xenopus (Silurana) tropicalis
445828 Xenopus laevis
451887 Pan troglodytes
733574 Xenopus (Silurana) tropicalis
100059818 Equus caballus
100453002 Pongo abelii
100473385 Ailuropoda melanoleuca
100542045 Meleagris gallopavo
100558921 Anolis carolinensis
100595184 Nomascus leucogenys
29127 Homo sapiens
431862 Xenopus laevis
486549 Canis lupus familiaris
514618 Bos taurus
100517651 Sus scrofa
426884 Gallus gallus
100354099 Oryctolagus cuniculus
100721177 Cavia porcellus
26934 Mus musculus
315298 Rattus norvegicus
323197 Danio rerio
Ausgewählte Anbieter für anti-RACGAP1 (RACGAP1) Antikörper
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