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RIOK3 was identified by the similarity of its product to the Aspergillus nidulans SUDD protein, an extragenic suppressor of the heat-sensitive bimD6 mutation that fails to attach properly to the spindle microtubules at a restrictive temperature. Zusätzlich bieten wir Ihnen RRIO Kinase 3 Antikörper (48) und RRIO Kinase 3 Kits (5) und viele weitere Produktgruppen zu diesem Protein an.
Showing 5 out of 6 products:
RIO kinase 3 (RIOK3) positively regulates the activity of the AKT/mTOR pathway in glioma cells.
the ectopic expression of RIOK3 or a phosphomimetic MDA5-S828D mutation attenuated MDA5-mediated signaling.
These findings demonstrate that RIOK3 is necessary for maintaining actin cytoskeletal organisation required for migration and invasion, biological processes that are necessary for hypoxia-driven metastasis.
Functionally, RIOK3 acts as a SUFU-dependent positive regulator of Hedgehog signaling.
Authors found that RIOK3 physically interacts with TBK1 and IRF3 and bridges the functions between TBK1 and IRF3 in the activation of type I interferon pathway.
RioK3 is a novel cytoplasmic component of pre-40S pre-ribosomal particle(s) in human cells, required for normal processing of the 21S pre-rRNA.
Like RIOK3, PAK4 promotes pancreas ductal cell motility and invasion in pancreatic cancer
down-regulation of miR-191 is essential for erythroid chromatin condensation and enucleation by allowing up-regulation of Riok3 and Mxi1
This gene was identified by the similarity of its product to the Aspergillus nidulans SUDD protein, an extragenic suppressor of the heat-sensitive bimD6 mutation that fails to attach properly to the spindle microtubules at a restrictive temperature. The specific function of this gene has not yet been determined.
homolog of the Aspergillus nidulans sudD gene product
, serine/threonine-protein kinase RIO3
, sudD (suppressor of bimD6, Aspergillus nidulans) homolog
, sudD homolog
, sudD suppressor of Aspergillus nidulans bimD6 homolog
, sudD suppressor of bimD6 homolog
, sudD, suppressor of bimD6 homolog
, RIO kinase 3