RER1 Retention in Endoplasmic Reticulum 1 Homolog (S. Cerevisiae) Proteine (RER1)

The protein encoded by RER1 is a multi-pass membrane protein that is localized to the golgi apparatus. Zusätzlich bieten wir Ihnen RER1 Antikörper (31) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
RER1 11079 O15258
RER1 67830 Q9CQU3
Ratte RER1 RER1 298675 Q498C8
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 50 bis 55 Tage
$7,626.01
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Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 50 bis 55 Tage
$5,355.45
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$814.00
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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RER1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine)

Weitere Proteine zu RER1 Retention in Endoplasmic Reticulum 1 Homolog (S. Cerevisiae) (RER1) Interaktionspartnern

Human RER1 Retention in Endoplasmic Reticulum 1 Homolog (S. Cerevisiae) (RER1) Interaktionspartner

  1. RER1 is a novel and potential important mediator of elevated alphaSyn levels

  2. Rer1p regulates the ER retention of immature or misfolded rhodopsin (zeige RHO Proteine) and modulates its intracellular trafficking through the early secretory pathway.

  3. Charcot-Marie-Tooth disease-related PMP22 (zeige PMP22 Proteine) is trapped in the endoplasmic reticulum by calnexin (zeige CANX Proteine)-dependent retention and Rer1-mediated early Golgi retrieval systems and partly degraded by the Hrd1 (zeige SYVN1 Proteine)-mediated endoplasmic reticulum-associated degradation system.

  4. Rer1p depletion reduced ciliary length and function by increasing gamma-secretase complex assembly and activity and, consequently, enhancing Notch (zeige NOTCH1 Proteine) signaling as well as reducing Foxj1a expression.

  5. Synoviolin up-regulates amyloid beta production by targeting a negative regulator of gamma-secretase, Rer1, for degradation.

  6. RER1 modulates amyloid-beta production by altering trafficking of gamma-secretase and amyloid precursor protein (zeige APP Proteine).

  7. Downregulation of Rer1 leads to increased surface localization of Pen2 (zeige PSENEN Proteine), whereas overexpression of Rer1 stabilizes unassembled Pen2 (zeige PSENEN Proteine). Rer1 is the first identified interaction partner of mammalian transmembrane-based retention/retrieval signals.

Zebrafish RER1 Retention in Endoplasmic Reticulum 1 Homolog (S. Cerevisiae) (RER1) Interaktionspartner

  1. Rer1p depletion reduced ciliary length and function by increasing gamma-secretase complex assembly and activity and, consequently, enhancing Notch (zeige NOTCH1 Proteine) signaling as well as reducing Foxj1a expression.

Mouse (Murine) RER1 Retention in Endoplasmic Reticulum 1 Homolog (S. Cerevisiae) (RER1) Interaktionspartner

  1. Rer1 is a functionally important unique factor that controls surface expression of muscle acetylcholine receptors by localizing unassembled alpha-subunits to the early secretory pathway

RER1 Protein Überblick

Protein Überblick

The protein encoded by this gene is a multi-pass membrane protein that is localized to the golgi apparatus. It is involved in the retention of endoplasmic reticulum (ER) membrane proteins in the ER and retrieval of ER membrane proteins from the early Golgi compartment to facilitate gamma-secretase complex assembly.

Genbezeichner und Symbole assoziert mit RER1

  • retention in endoplasmic reticulum sorting receptor 1 (RER1)
  • retention in endoplasmic reticulum sorting receptor 1 (rer1)
  • RER1 retention in endoplasmic reticulum 1 homolog (S. cerevisiae) (rer1)
  • retention in endoplasmic reticulum sorting receptor 1 L homeolog (rer1.L)
  • retention in endoplasmic reticulum sorting receptor 1 (Rer1)
  • 1110060F11Rik Protein
  • 5830454N22Rik Protein
  • AU043380 Protein
  • DKFZp459K116 Protein
  • rer1 Protein
  • RGD1306324 Protein
  • zgc:65968 Protein

Bezeichner auf Proteinebene für RER1

RER1 retention in endoplasmic reticulum 1 homolog , Protein RER1 , protein RER1 , RER1 protein

GENE ID SPEZIES
100173680 Pongo abelii
100528148 Ictalurus punctatus
100195191 Salmo salar
100301728 Oncorhynchus mykiss
446675 Xenopus laevis
11079 Homo sapiens
393648 Danio rerio
419397 Gallus gallus
479578 Canis lupus familiaris
100125922 Bos taurus
67830 Mus musculus
298675 Rattus norvegicus
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