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The RABL2B protein is a member of the RAB gene family which belongs to the RAS GTPase superfamily. Zusätzlich bieten wir Ihnen RAB, Member of RAS Oncogene Family-Like 2B Antikörper (14) und und viele weitere Produktgruppen zu diesem Protein an.
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The findings of the present study suggest that the difference in semen quality in bulls with different RABL2B genotypes is generated via an alternative splicing mechanism caused by a functional SNP within the exonic splicing enhancer motif.
In human samples no deviations of the euploid genomic state could be detected indicating that 22q13 microdeletions involving RABL2B are rare.
According to the present study, 50776482 delC allele in the RABL2B gene could be a risk factor in Iranian infertile men with oligoasthenoteratozoospermia defect, but more genetic studies are required to understand the accurate role of this variant in pathogenesis of human male infertility.
CEP19 is recruited to the ciliary base by the centriolar CEP350/FOP (zeige ACRV1 Proteine) complex and then specifically captures GTP (zeige AK3 Proteine)-bound RABL2B, which is activated via its intrinsic nucleotide exchange.
The RABL2B protein is a member of the RAB gene family which belongs to the RAS GTPase superfamily. RABL2B is located within a subtelomeric region of 22q13.3. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene.
RAB, member of RAS oncogene family-like 2B
, rab-like protein 2A
, RAB, member of RAS oncogene family-like 2A
, rab-like protein 2B