Protein tyrosine Phosphatase, Receptor Type, R Proteine (PTPRR)

The protein encoded by PTPRR is a member of the protein tyrosine phosphatase (PTP) family. Zusätzlich bieten wir Ihnen Protein tyrosine Phosphatase, Receptor Type, R Antikörper (99) und Protein tyrosine Phosphatase, Receptor Type, R Kits (12) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
PTPRR 5801 Q15256
PTPRR 94202 O08617
PTPRR 19279 Q62132
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 50 bis 55 Tage
$5,355.45
Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$5,465.26
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Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$5,465.26
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Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$814.00
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Wheat germ Human GST tag 2 μg Anmelden zum Anzeigen 11 bis 12 Tage
$338.33
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,489.67
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Escherichia coli (E. coli) Human His-SUMO Tag   100 μg Anmelden zum Anzeigen 11 Days
$411.40
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PTPRR Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , ,
, , , ,
Rat (Rattus)

Mouse (Murine) ,
,

Weitere Proteine zu Protein tyrosine Phosphatase, Receptor Type, R (PTPRR) Interaktionspartnern

Human Protein tyrosine Phosphatase, Receptor Type, R (PTPRR) Interaktionspartner

  1. The PTPRR genes were related to possible endophenotypes for suicidal behaviour such as anger, depression-anxiety and fatigue.

  2. The development of MDD may be related with the polymorphism of ERK (zeige EPHB2 Proteine)-rs12678428 and PTPRR-rs1513105.

  3. Results show that PTPRR is an early and direct target of the androgen receptor which negatively regulates the RAS/ERK1/2 pathway suggesting that its loss in prostate cancer cells is one factor that might contribute to activation of the RAS/ERK1/2 pathway.

  4. High expression of PTP receptors R and Z1 was observed in all examined cases of colorectal carcinoma, adenoma and normal colon tissue in this study.

  5. The methylation index of PTPRR recovered from scrapings of uterine cervix adenocarcinomas is significantly higher than in normal controls.

  6. 3 genes identified by association study and supported by ocular expression and/or replication, UHRF1BP1L, PTPRR, and PPFIA2, are novel candidates for myopic development within the MYP3 locus that should be further studied.

  7. Methylation of the PTPRR promoter has an important role in the metastasis and may be a biomarker of invasive cervical cancer

  8. the protein tyrosine phosphatase receptor type R gene may play a role in conferring risk of major depressive disorder in females

  9. expression of the PTPRR-1 isoform was inactivated in colorectal cancer cells as a result of de novo CpG island methylation and enrichment of transcription-repressive histone-tail marks, mainly H3K27me3

  10. determined high-resolution structures of all of the human family members of Mitogen-Activated Protein Kinase (zeige MAPK1 Proteine)-specific protein tyrosine phosphatases

Mouse (Murine) Protein tyrosine Phosphatase, Receptor Type, R (PTPRR) Interaktionspartner

  1. These findings indicate an important role for PTPRR in maintaining low basal mitogen-activated protein kinase (zeige MAPK1 Proteine) activity in Purkinje cells.

  2. The data of this study disclosed a distinct role for PTPRR in recognition memory and exploration of a new environment.

  3. Results support the suggested link between PTPRR isoforms and cerebellar calcium ion homeostasis, and suggest an additional role in the process of cell-cell adhesion

  4. The ERK2 (zeige MAPK1 Proteine) docking groove is more restrictive and selective for its tyrosine phosphatase inactivators than for MEK1 (zeige MAP2K1 Proteine)/2 and indicate that distinct ERK2 (zeige MAPK1 Proteine) residues modulate the docking interactions with activating and inactivating effectors.

  5. PTPBR7, was subject to N-terminal proteolytic processing, in between amino acid position 136 and 137, resulting in an additional, 65-kDa transmembrane PTPRR isoform.

  6. Ptprr-/- mice displayed ataxia characterized by defects in fine motor coordination and balance skills.

  7. PTP-SL, like PTPBR7, is a single membrane-spanning receptor-type protein tyrosine phosphatases.

Protein tyrosine Phosphatase, Receptor Type, R (PTPRR) Protein Überblick

Protein Überblick

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. Silencing of this gene has been associated with colorectal cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares a symbol (PTPRQ) with another gene, protein tyrosine phosphatase, receptor type, Q (GeneID 374462), which is also located on chromosome 12.

Genbezeichner und Symbole assoziert mit PTPRR

  • protein tyrosine phosphatase, receptor type R (PTPRR)
  • protein tyrosine phosphatase, receptor type, R (Ptprr)
  • protein tyrosine phosphatase, receptor type R L homeolog (ptprr.L)
  • protein tyrosine phosphatase, receptor type R (ptprr)
  • protein tyrosine phosphatase, receptor type, r (ptprr)
  • receptor-type tyrosine-protein phosphatase R (LOC100715069)
  • ec-ptp Protein
  • Gmcp1 Protein
  • mPTP213 Protein
  • pcptp1 Protein
  • ptp-sl Protein
  • ptpbr7 Protein
  • PTPRQ Protein
  • PTPRR Protein
  • RPTPRR Protein

Bezeichner auf Proteinebene für PTPRR

Ch-1 PTPase , NC-PTPCOM1 , R-PTP-R , ch-1PTPase , protein tyrosine phosphatase Cr1PTPase , protein-tyrosine phosphatase NC-PTPCOM1 , protein-tyrosine phosphatase PCPTP1 , receptor-type tyrosine-protein phosphatase R , PC12-PTP1 , protein tyrosine phosphatase PCPTP1 , tyrosine phosphatase CBPTP , protein tyrosine phosphatase, receptor type, R , protein tyrosine phosphatase, receptor type, Q , Receptor-type tyrosine-protein phosphatase R , receptor-type tyrosine-protein phosphatase R-like , STEP-like PTPase , phosphotyrosine phosphatase 13 , protein-tyrosine-phosphatase SL , protein-tyrosine-phosphatase-SL

GENE ID SPEZIES
5801 Homo sapiens
94202 Rattus norvegicus
398636 Xenopus laevis
452076 Pan troglodytes
481163 Canis lupus familiaris
536337 Bos taurus
718582 Macaca mulatta
771985 Gallus gallus
100015968 Monodelphis domestica
100063646 Equus caballus
100125100 Xenopus (Silurana) tropicalis
100154962 Sus scrofa
100172750 Pongo abelii
100226660 Taeniopygia guttata
100351238 Oryctolagus cuniculus
100398974 Callithrix jacchus
100474182 Ailuropoda melanoleuca
100526652 Danio rerio
100549190 Meleagris gallopavo
100567785 Anolis carolinensis
100583678 Nomascus leucogenys
19279 Mus musculus
100715069 Cavia porcellus
101121162 Ovis aries
Ausgewählte Anbieter für Protein tyrosine Phosphatase, Receptor Type, R Proteine (PTPRR)
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