Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) Proteine (PTGS1)

This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. Zusätzlich bieten wir Ihnen PTGS1 Antikörper (179) und PTGS1 Kits (75) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
PTGS1 19224 P22437
PTGS1 24693 Q63921
PTGS1 5742 P23219
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Top PTGS1 Proteine auf antikoerper-online.de

Showing 8 out of 10 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$9,797.11
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$9,797.11
Details
Escherichia coli (E. coli) Maus His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$822.00
Details
Escherichia coli (E. coli) Ratte His tag,T7 tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$736.00
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Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$800.00
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 2 bis 3 Tage
$814.00
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Wheat germ Human GST tag 2 μg Anmelden zum Anzeigen 11 bis 12 Tage
$225.40
Details
Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$3,653.83
Details

PTGS1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine) ,

Rat (Rattus) ,
,
Human , , ,
, , ,

Weitere Proteine zu Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS1) Interaktionspartnern

Horse (Equine) Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS1) Interaktionspartner

  1. This study showed that COX-1 and COX-2 (zeige PTGS2 Proteine) in genital carcinomas in the horse is poor; microsomal PGES (zeige PTGES Proteine)-1 is more prominently expressed.

  2. COX-1 and COX-2 (zeige PTGS2 Proteine) genes were constitutively expressed in baseline samples. Low-flow ischemia resulted in significant upregulation of COX-2 (zeige PTGS2 Proteine) gene expression at each subsequent time point, compared with baseline values.

  3. In this study, both COX-1 and COX-2 (zeige PTGS2 Proteine) were expressed in the colon before induced ischemia; ischemic injury increased expression of COX-2 (zeige PTGS2 Proteine).

  4. Immunoreactivity for COX-1 and COX-2 (zeige PTGS2 Proteine) is high in equine corneal SCC (zeige CYP11A1 Proteine), possibly indicating that COX (zeige CPOX Proteine) plays a role in oncogenesis or progression of this tumor type at this site.

Rabbit Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS1) Interaktionspartner

  1. These results suggest that licochalcones inhibit collagen-induced platelet aggregation accompanied by inhibition of COX-1 activity.

Mouse (Murine) Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS1) Interaktionspartner

  1. IFNgamma upregulated microsomal prostaglandin E synthase-1 (mPGES-1 (zeige PTGES Proteine)) alongside cyclo-oxygenase (COX-1) within macrophage populations, resulting in sustained prostaglandin (PG)E2 biosynthesis.

  2. Data (including data from studies in knockout mice) suggest that delayed parturition in Cox-1 knockout mice is result of impaired luteolysis and cervical dilation, despite the presence of strong uterine contractions.

  3. Data suggest that Il4 (zeige IL4 Proteine) (usually released from helper T-cells) induces Cox1 in macrophages at post-transcriptional level; activation of Ampk (zeige PRKAA1 Proteine) (catalytic subunit Prkaa1 (zeige PRKAA1 Proteine)) by metformin blocks Il4 (zeige IL4 Proteine)-dependent induction of Cox1 and blocks macrophage polarization/activation. (Il4 (zeige IL4 Proteine) = interleukin-4 (zeige IL4 Proteine); Cox1 = cyclooxygenase 1; Ampk (zeige PRKAA1 Proteine) = AMP-activated protein kinase (zeige PRKAA2 Proteine))

  4. Specific inhibition of PGE2 synthesis by targeting mPGES-1 (zeige PTGES Proteine) may weaken host defense against bacterial infections.

  5. Dimethyl ester of bilirubin exhibits anti-inflammatory activity through inhibition of secretory phospholipase A2 (zeige YWHAZ Proteine), lipoxygenase and cyclooxygenase.

  6. role of cyclooxygenase-1 and -2 in endothelium-dependent contraction of atherosclerotic mouse abdominal aortas

  7. Suggest the expression of COX-1 and COX-2 in the urothelium protects bladder damage from radiation.

  8. COX-1 inhibitor SC-560 has a protective effect on the thromboxane A2-mediated decrease in renal function in response to endotoxin.

  9. Expression of COX-1 is essential for the protection of liver against chemical-induced hepatotoxicity and required for hepatic homeostatic maintenance.

  10. Data suggest that multitarget FAAH (zeige FAAH Proteine)/Cox (zeige CPOX Proteine) blockade may provide a transformative approach to inflammatory bowel disease (IBD) and other pathologies in which fatty acid amide hydrolase (zeige FAAH Proteine)/cyclooxygenases (FAAH (zeige FAAH Proteine), Cox-1, and Cox-2) are overactive.

Cow (Bovine) Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS1) Interaktionspartner

  1. there was no expression of COX-1, either mRNA or protein, on any day of the estrous cycle

Human Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS1) Interaktionspartner

  1. Prostaglandin D2 generation from human lung mast cells is catalysed exclusively by cyclooxygenase-1

  2. Extracellular histones disarrange vasoactive mediators release through a COX1-COX2-eNOS (zeige NOS3 Proteine) interaction in human endothelial cells.

  3. Results suggested that in Chinese Han patients with stroke taking aspirin for secondary prevention, PTGS1 polymorphisms may increase the risk of poor functional outcomes and this effect may be modulated by the smoking status. PTGS1 gene-smoking interaction might in part reflect the heterogeneity in the prognosis of patients treated with aspirin.

  4. analysis of co-existing variants in both F8 and PTGS-1 genes in a three-generation pedigree of hemophilia A; the PTGS-1 variant was associated with specific functional defects in the arachidonic acid pathway and more severe hemorrhage.

  5. Data suggest expression of PTGS1 in colon is significantly correlated with expression of PTGS2 (zeige PTGS2 Proteine), PTGES1, PTGER2 (zeige PTGER2 Proteine), and PTGER4 (zeige PTGER4 Proteine); this study was conducted in individuals at high risk for colon cancer treated with Mediterranean diet versus a Healthy Eating diet for prevention of colon cancer. (PG = prostaglandin; PTGS2 (zeige PTGS2 Proteine) = PG-endoperoxide synthase 2; PTGES1 = PGE (zeige LIPF Proteine) synthase protein; PTGER2 (zeige PTGER2 Proteine) = PGE (zeige LIPF Proteine) receptor 2; PTGER4 (zeige PTGER4 Proteine) = PGE (zeige LIPF Proteine) receptor 4)

  6. Dimethyl ester of bilirubin exhibits anti-inflammatory activity through inhibition of secretory phospholipase A2 (zeige YWHAZ Proteine), lipoxygenase and cyclooxygenase.

  7. Panax quinquefolium saponin attenuated HUVEC apoptosis and improved the dual antiplatelet-mediated reduction of platelet adhesion to injured HUVECs and the underlying mechanisms may be associated with PI3K (zeige PIK3CA Proteine)/AKT (zeige AKT1 Proteine) and COX (zeige COX8A Proteine) pathways.

  8. The interactions of COX (zeige COX8A Proteine)-1of rs3842787 and cox-2 of rs20417 were associated with aspirin resistance of stroke.

  9. We provide the first report that pro-angiogenic genes PECAM1 (zeige PECAM1 Proteine), PTGS1, FGD5 (zeige FGD5 Proteine), and MCAM (zeige MCAM Proteine) may play a vital role in pathological dermal angiogenesis disorders of psoriasis.

  10. a new neutrophil-activating platelet-derived lipid generated by COX-1 is presented that can activate or prime human neutrophils, suggesting a role in innate immunity and acute inflammation.

Pig (Porcine) Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS1) Interaktionspartner

  1. Brain death increases the expression of COX-1 and COX-2 (zeige PTGS2 Proteine) mRNA in the renal medulla

  2. Endometrial prostaglandin-endoperoxide synthase 1 (PTGS1) mRNA expression increased 2- to 3-fold after Day 10 of the estrous cycle and pregnancy, whereas PTGS2 (zeige PTGS2 Proteine) mRNA expression increased 76-fold between Days 5 and 15 of the estrous cycle and pregnancy.

PTGS1 Protein Überblick

Protein Überblick

This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit PTGS1

  • prostaglandin-endoperoxide synthase 1 (PTGS1)
  • cyclooxygenase-1 (cox-1)
  • prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) (PTGS1)
  • prostaglandin-endoperoxide synthase 1 (Ptgs1)
  • prostaglandin-endoperoxide synthase 1 (ptgs1)
  • prostaglandin-endoperoxide synthase 1 S homeolog (ptgs1.S)
  • Cox-1 Protein
  • COX-3 Protein
  • cox1 Protein
  • COX3 Protein
  • PCOX1 Protein
  • PES-1 Protein
  • PGG/HS Protein
  • PGHS-1 Protein
  • PGHS1 Protein
  • PHS1 Protein
  • PHS 1 Protein
  • PTGHS Protein
  • Ptgs1 Protein
  • zCOX-1 Protein

Bezeichner auf Proteinebene für PTGS1

cyclooxygenase-1 , prostaglandin G/H synthase 1 , prostaglandin G/H synthase and cyclooxygenase , prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) , PGH synthase 1 , PGHS-1 , PHS 1 , prostaglandin H2 synthase 1 , prostaglandin-endoperoxide synthase 1 , cyclooxygenase 1 , COX-1 , cyclooxygenase 3 , Cox-1 , Cox-1b , prostaglandin endoperoxide synthase , cyclooxygenase

GENE ID SPEZIES
100034087 Equus caballus
100136038 Oncorhynchus mykiss
427752 Gallus gallus
464713 Pan troglodytes
698213 Macaca mulatta
100585600 Nomascus leucogenys
100009407 Oryctolagus cuniculus
19224 Mus musculus
24693 Rattus norvegicus
246226 Danio rerio
282022 Bos taurus
5742 Homo sapiens
443551 Ovis aries
403544 Canis lupus familiaris
397541 Sus scrofa
100037245 Xenopus laevis
Ausgewählte Anbieter für PTGS1 Proteine (PTGS1)
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