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KCNK9 encodes a member of the superfamily of potassium channel proteins containing two pore-forming P domains, and is highly expressed in the cerebellum. Zusätzlich bieten wir Ihnen KCNK9 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.
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Mouse (Murine) Monoclonal KCNK9 Primary Antibody für ICC, IHC - ABIN2115251
Dadi, Luo, Vierra, Jacobson: TASK-1 Potassium Channels Limit Pancreatic ?-Cell Calcium Influx and Glucagon Secretion. in Molecular endocrinology (Baltimore, Md.) 2015
Show all 2 Pubmed References
In conclusion, we have identified the first selective activator of the two-pore domain potassium channel TASK3.
KCNK9 imprinting syndrome is a rare cause of intellectual disability, congenital hypotonia, palatal abnormalities, and occasional seizures.
Our results provide evidence for new loci influencing abdominal visceral (BBS9 (zeige BBS9 Antikörper), ADCY8 (zeige ADCY8 Antikörper), KCNK9) and subcutaneous (MLLT10 (zeige MLLT10 Antikörper)/DNAJC1 (zeige DNAJC1 Antikörper)/EBLN1 (zeige EBLN2 Antikörper)) fat, and confirmed a locus (THNSL2 (zeige THNSL2 Antikörper)) previously reported to be associated with abdominal fat in women.
TASK-1 (zeige KCNK3 Antikörper) and TASK-3 may form heterodimers in human atrial cardiomyocytes.
During conductance simulation experiments, both TASK-3 and TREK-1 (zeige KCNK2 Antikörper) channels were able to repolarise the membrane once AP threshold was reached
The findings of this study suggest that variations in KCNK9 genes are associated with both mild and severe persistent breast pain after breast cancer surgery.
Diacylglycerol mediates regulation of TASK1 and TASK3 potassium channels by GNAQ.
Interference with TASK-3 channel expression, therefore, induces caspase (zeige CASP3 Antikörper)-dependent and -independent apoptosis of melanoma cells, most likely via causing mitochondrial depolarization.
K2P3.1 (zeige KCNK3 Antikörper) and K2P9.1 undergo rapid dynamin (zeige DNM1 Antikörper)-dependent endocytosis
Mutations of KCNK9 or epigenetic disturbances within the PEG13 imprinted cluster do not significantly contribute to the cause of the developmental disabilities tested in this study.
results demonstrate that neurotensin (NT (zeige NTS Antikörper)) transiently increased the neuronal excitability of dentate gyrus granule cells (GCs (zeige UGCG Antikörper)) by inhibiting TASK-3 channels; NT-mediated increases in neuronal excitability facilitate long-term potentiation at the perforant path-GC synapses
KCNK9 channels are not involved in hearing.
THe results of this study suggested that dysfunction of KCNK9 causes a migration defect in the cortex via an activity-dependent mechanism.
Oxygen and mitochondrial inhibitors modulate both monomeric and heteromeric TASK-1 (zeige KCNK3 Antikörper) and TASK-3 channels in mouse carotid body type-1 cells.
Data indicate that in 1-day-old Task3-/- mice, renal renin (zeige REN Antikörper) concentration was lower than in wild-type mice.
DPP6 (zeige DPP6 Antikörper) co-expression with TASK-3 results in the formation of a protein complex that enhances resting membrane potassium conductance.
An extracellular ion pathway plays a central role in the cooperative gating of a K(2P) K+ channel (zeige KCNC4 Antikörper) by extracellular pH
Task3 plays an important role in the adaptation of aldosterone secretion to dietary salt intake.
This study demonistrated that kcnk9 gene expression in mouse dorsal raphe nucleus
TASK3 channel genes may contribute to the development of low renin (zeige REN Antikörper) essential hypertension and idiopathic hyperaldosteronism in mice.
This gene encodes a member of the superfamily of potassium channel proteins containing two pore-forming P domains, and is highly expressed in the cerebellum. Amplification and overexpression of this gene has been observed in several types of human carcinomas, notably in breast cancer. This gene is imprinted in fetal brain, with preferential expression from the maternal allele.
potassium channel, subfamily K, member 9
, TWIK-related acid-sensitive K(+) channel 3
, TWIK-related acid-sensitive K+ channel 3
, acid-sensitive potassium channel protein TASK-3
, potassium channel TASK3
, potassium channel subfamily K member 9
, two pore K(+) channel KT3.2
, two pore potassium channel KT3.2
, potassium channel subfamily K member 9 (Task-3)
, potassium channel, subfamily K, member 9 (Task-3)
, TASK-1 potassium channel