Poly (ADP-Ribose) Polymerase Family, Member 3 Proteine (PARP3)

The protein encoded by PARP3 belongs to the PARP family. Zusätzlich bieten wir Ihnen PARP3 Antikörper (103) und und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
PARP3 10039 Q9Y6F1
Maus PARP3 PARP3 235587  
Ratte PARP3 PARP3 300985  
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Showing 6 out of 6 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
Baculovirus infected Insect Cells Human GST tag,His tag 100 μg Anmelden zum Anzeigen 20 bis 21 Tage
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
Insect cells (Sf21) Human HA tag,His tag   10 μg Anmelden zum Anzeigen 5 bis 8 Tage
Insect cells (Sf9) Human Unkonjugiert   20 μg Anmelden zum Anzeigen 11 bis 16 Tage

PARP3 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , , ,
, , , ,

Weitere Proteine zu Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3) Interaktionspartnern

Zebrafish Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3) Interaktionspartner

  1. Parp3 is crucial in the early stages of zebrafi (zeige ARHGEF16 Proteine)sh development, possibly by exerting its transcriptional regulatory functions as early as during the specification of the neural plate border

Human Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3) Interaktionspartner

  1. PARP3 controls of TGFbeta (zeige TGFB1 Proteine)-induced epithelial mesenchymal transformation and acquisition of stem-like cell features by stimulation transglutaminase 2 (zeige TGM2 Proteine)/SNAI1 (zeige SNAI1 Proteine) signaling.

  2. Data indicate that PARP3, a DNA damage-activated ADP-ribosyltransferase, can mono-ADP-ribosylate double-stranded DNA ends.

  3. In a process of single-strand DNA repair, PARP3 mono-ADP-ribosylates nucleosomal histone H2B.

  4. we found that PARP3 interacted with FoxM1 (zeige FOXM1 Proteine) to enhance its transcriptional activity and conferred glioblastoma cell radioresistance. Thus, our data suggest that PARP3 could be a therapeutic target to overcome radioresistance in glioblastoma

  5. Identification of ADP-ribosylation sites in PARP3 and the determination of the extent ofpoly(ADP-ribosyl)ated residues in this protein was performed.

  6. MiR (zeige MLXIP Proteine)-630 reduced apoptosis by downregulating several apoptotic modulators, PARP3, DDIT4 (zeige DDIT4 Proteine), and EP300 (zeige EP300 Proteine).

  7. In some cancer cells, repression of PARP3 could be responsible for an increased telomerase activity.

  8. PARP3 likely facilitates the recruitment of Ku80 (zeige XRCC5 Proteine) to double strand breaks to antagonize DNA end resection but facilitate Ku-mediated accurate classical non-homologous end-joining.

  9. PARP3 gene occupancy in the human neuroblastoma (zeige ARHGEF16 Proteine) cell line SK-N-SH occurs preferentially with developmental genes regulating cell fate specification, tissue patterning, craniofacial development and neurogenesis.

  10. PARP3 is a critical player in the stabilization of the mitotic spindle and in telomere integrity by associating and regulating the mitotic components NuMA and tankyrase 1 (zeige TNKS Proteine).

Mouse (Murine) Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3) Interaktionspartner

  1. We show that Poly(ADP)ribose polymerase 3 (Parp3), an enzyme recently implicated in DNA repair, contributes to antibody diversification by negatively regulating class switch recombination without affecting somatic hypermutation.

  2. PARP-3 has a role in chromosomal DNA double-strand break repair.

  3. We cloned and sequenced the cDNAs of the mouse PARP-3 (Adprt3) gene encoding poly(ADP-ribose) polymerase 3 and of the closely linked U3-55k (zeige RRP9 Proteine) gene coding for the U3 small nucleolar ribonucleoprotein complex-associated 55-kilodalton protein.

PARP3 Protein Überblick

Protein Überblick

The protein encoded by this gene belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This gene encodes the poly(ADP-ribosyl)transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified.

Genbezeichner und Symbole assoziert mit PARP3

  • seed maturation protein PM38 (PARP3)
  • poly (ADP-ribose) polymerase family, member 3 (parp3)
  • poly(ADP-ribose) polymerase family member 3 (PARP3)
  • poly(ADP-ribose) polymerase family member 3 L homeolog (parp3.L)
  • poly(ADP-ribose) polymerase family member 3 (parp3)
  • poly (ADP-ribose) polymerase family, member 3 (Parp3)
  • A930002C11Rik Protein
  • ADPRT-3 Protein
  • Adprt3 Protein
  • ADPRTL2 Protein
  • ADPRTL3 Protein
  • ARTD3 Protein
  • AW990611 Protein
  • fj17c06 Protein
  • IRT1 Protein
  • pADPRT-3 Protein
  • PARP-3 Protein
  • parp3 Protein
  • PM38 Protein
  • wu:fj17c06 Protein
  • zgc:66157 Protein

Bezeichner auf Proteinebene für PARP3

NAD(+) ADP-ribosyltransferase 3 , poly [ADP-ribose] polymerase 3 , poly[ADP-ribose] synthase 3 , ADP-ribosyltransferase (NAD+; poly (ADP-ribose polymerase)-like 3 , poly (ADP-ribose) polymerase family, member 3 , Poly synthetase 3 , poly [ADP-ribose] polymerase 3-like , ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 2 , ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 3 , ADP-ribosyltransferase diphtheria toxin-like 3 , ADPRT-3 , NAD+ ADP-ribosyltransferase 3 , poly(ADP-ribose) synthetase-3 , poly[ADP-ribose] synthetase 3 , A DP-ribosyltransferase (NAD+; poly (ADP-ribose polymerase)-like 3 , ADP-ribosyltransferase (NAD+, poly (ADP-ribose polymerase)-like 3 , Poly[ADP-ribose] synthetase-3 , poly (ADP-ribosyl) transferase-like 3

548024 Glycine max
335495 Danio rerio
460409 Pan troglodytes
484745 Canis lupus familiaris
496154 Xenopus laevis
699294 Macaca mulatta
771158 Gallus gallus
100060729 Equus caballus
100145803 Xenopus (Silurana) tropicalis
100194925 Salmo salar
100301771 Oncorhynchus mykiss
100438948 Pongo abelii
100479913 Ailuropoda melanoleuca
100597938 Nomascus leucogenys
100344824 Oryctolagus cuniculus
10039 Homo sapiens
507426 Bos taurus
235587 Mus musculus
300985 Rattus norvegicus
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