anti-Paired Box 4 (PAX4) Antikörper

PAX4 is a member of the paired box (PAX) family of transcription factors.

Alle Antikörper anzeigen Gen GeneID UniProt
Anti-Human PAX4 PAX4 5078 O43316
Anti-Maus PAX4 PAX4 18506 P32115
Anti-Ratte PAX4 PAX4 83630 O88436
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Top anti-PAX4 Antikörper auf antikoerper-online.de

Showing 10 out of 69 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB Host:  Rabbit  Target Name:  PAX4  Sample Type:  Human Fetal Lung  Antibody Dilution:  1.0ug/ml WB Suggested Anti-PAX4 Antibody Titration:  0.2-1 ug/ml  Positive Control:  Jurkat cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-PAX4 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:1562500  Positive Control:  Human Stomach 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Hund Ziege Unkonjugiert EIA, WB   0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$462.00
Details
Human Ziege Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Human Brain, Cerebellum (formalin-fixed, paraffin-embedded) stained with PAX4 antibody ABIN462174 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Kidney (formalin-fixed, paraffin-embedded) stained with PAX4 antibody ABIN462174 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$727.83
Details
Human Kaninchen Unkonjugiert FACS, IHC (p), WB Western blot analysis of PAX4 antibody (Center) (ABIN390643) in CEM cell line lysates (35 µg/lane). PAX4 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human brain tissue reacted with PAX4 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Maus Unkonjugiert WB 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$507.83
Details
Human Ziege Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$610.50
Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of PAX4 antibody (Center) in CEM cell line lysates (35ug/lane). PAX4 (arrow) was detected using the purified Pab. 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Ziege Unkonjugiert ELISA, EIA, WB ELISA: PAX4 Antibody [NBP1-49863] - (1.5ug/ml) as the reporter used with the capture rabbit antibody (5ug/ml) Western Blot: PAX4 Antibody [NBP1-49863] - Analysis of PAX4 in Mouse Pancreas lysate (35ug protein in RIPA buffer) using NBP1-49863 at 0.2ug/ml. Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$485.88
Details

Am meisten referenzierte anti-PAX4 Antikörper

  1. Human Monoclonal PAX4 Primary Antibody für ELISA, WB - ABIN969341 : Zhang, Xiao, Liu, Zhu, Wenhui, Li, Yuan, Wang: The association of the PAX4 gene with type 1 diabetes in Han Chinese. in Diabetes research and clinical practice 2008 (PubMed)

  2. Cow (Bovine) Polyclonal PAX4 Primary Antibody für WB - ABIN2779444 : Zhang, Smyrk, Oliveira, Lohse, Zhang, Johnson, Lloyd: KIT is an independent prognostic marker for pancreatic endocrine tumors: a finding derived from analysis of islet cell differentiation markers. in The American journal of surgical pathology 2010 (PubMed)

  3. Human Polyclonal PAX4 Primary Antibody für ELISA, EIA - ABIN4343820 : Haaland, Scaduto, Maldonado, Mansouri, Nalini, Iyer, Patel, Guthikonda, Hampe, Balasubramanyam, Metzker: A-beta-subtype of ketosis-prone diabetes is not predominantly a monogenic diabetic syndrome. in Diabetes Care 2009 (PubMed)

Weitere Antikörper gegen PAX4 Interaktionspartner

Human Paired Box 4 (PAX4) Interaktionspartner

  1. Study identified the association of a PAX4 Asian-specific missense variant rs2233580 with type 2 diabetes in an exome-chip association analysis, supporting the involvement of PAX4 in the pathogenesis of type 2 diabetes.

  2. Viability of beta-cell was reduced under glucotoxic stress condition for the cells overexpressing either PAX4 R192H or PAX4 P321H or both. Thus these PAX4 polymorphisms may increase T2D risk by defective transcription regulation of target genes and/or decreased beta-cell survival in high glucose condition.

  3. PAX4 IVS7-1G>A contributes to the pathogenesis of diabetes in this maturity-onset diabetes of the young, type 9 family through beta-cell dysfunction

  4. The PAX4 variant rs6467136 was associated with the therapeutic effect of rosiglitazone in Chinese T2DM patients.

  5. PAX4-miR (zeige MLXIP Antikörper)-144/451-ADAMs axis regulates human epithelial cancer metastasis

  6. These data suggest that acute PAX4 overexpression can reduce expression of aristaless related homeobox and glucagon (zeige GCG Antikörper) during embryonic stem cell differentiation resulting in improved numbers of unihormonal insulin (zeige INS Antikörper)-positive cells.

  7. Tph1 (zeige TPH1 Antikörper) and increased EC cell number occurred before the onset of obesity and hyperleptinemi. In addition, leptin (zeige LEP Antikörper) deficiency was associated with reduced Pax4 mRNA, oral leptin (zeige LEP Antikörper) treatment enhanced both Tph1 (zeige TPH1 Antikörper) and Pax4 mRNA.

  8. MAFA (zeige KLRG1 Antikörper) nuclear expression in pancreatic alpha and beta cells, and the percentage of alpha cells expressing PAX4 are altered in patients with type 2 diabetes.

  9. PAX4 R192H polymorphism generated a protein with defect in transcriptional repressor activities on its target genes, which may lead to beta-cell dysfunction associated with maturity onset diabetes of the young and early onset-age of type 2 diabetes.

  10. A1168C polymorphism in PAX4 gene may not play an essential role in the genetic susceptibility of the islet autoantibody-negative ketosis-prone diabetes in Chinese Han population.

Mouse (Murine) Paired Box 4 (PAX4) Interaktionspartner

  1. Down-regulation of PAX4 or its target gene encoding the p97/VCP (zeige vcp Antikörper) ATPase (zeige DNAH8 Antikörper) reduced myofibril disassembly.

  2. Ectopic expression of Pax4 in pancreatic delta cells results in beta-like cell neogenesis.

  3. The coordinated regulation of distinct cellular pathways particularly related to ER homeostasis by PAX4 not achieved by the mutant variant PAX4R129W alleviates beta cell degeneration and protects against diabetes mellitus.

  4. This work establishes the existence of a bona fide PAX4-enriched cell subpopulation nested within pancreatic islets that can expand in periods of increased functional demands, and exhibit improved viability in response to pathophysiological situations.

  5. Pax4 expression is not sufficient to transduce pancreatic alpha cells into beta cells. Overexpression of Pax4 in alpha cells may not increase functional beta cell number in diabetic patients

  6. Adult glucagon (zeige GCG Antikörper) producing cells can be converted into beta-like cells upon Pax4 misexpression.

  7. RBM4 (zeige RBM4 Antikörper) promoted insulin (zeige INS Antikörper) gene expression by altering the isoform balance of the transcription factors Isl1 (zeige ISL1 Antikörper) and Pax4 via alternative splicing control.

  8. these finding demonstrate that, downstream of Neurog3 (zeige NEUROG3 Antikörper), the specification of a subset of enteroendocrine subtypes relies on both Arx and Pax4, while others depend only on Arx or Pax4.

  9. Pax4 protects adult islets from stress-induced apoptosis by suppressing selective nuclear factor-kappaB target genes while increasing Bcl-2 (zeige BCL2 Antikörper) levels.

  10. Pax4 has a role in facilitating embryonic stem cell differentiation into the pancreatic lineage

PAX4 Antigen-Profil

Protein Überblick

This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The paired box 4 gene is involved in pancreatic islet development and mouse studies have demonstrated a role for this gene in differentiation of insulin-producing beta cells.

Genbezeichner und Symbole assoziert mit anti-Paired Box 4 (PAX4) Antikörper

  • paired box 4 (PAX4) Antikörper
  • paired box 4 (Pax4) Antikörper
  • KPD Antikörper
  • MODY9 Antikörper
  • Pax-4 Antikörper
  • PAX4 Antikörper

Bezeichner auf Proteinebene für anti-Paired Box 4 (PAX4) Antikörper

paired box gene 4 , paired box protein Pax-4 , paired domain gene 4 , paired box 4 , paired-box gene 4 , paired box protein Pax-4-like

GENE ID SPEZIES
5078 Homo sapiens
18506 Mus musculus
83630 Rattus norvegicus
472503 Pan troglodytes
482268 Canis lupus familiaris
554328 Ovis aries
698351 Macaca mulatta
100137394 Papio anubis
100354681 Oryctolagus cuniculus
100402138 Callithrix jacchus
100588587 Nomascus leucogenys
526172 Bos taurus
100715909 Cavia porcellus
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