anti-Neuronal PAS Domain Protein 4 (NPAS4) Antikörper

NXF is a member of the basic helix-loop-helix-PER (MIM 602260)-ARNT (MIM 126110)-SIM (see SIM2\; MIM 600892) (bHLH-PAS) class of transcriptional regulators, which are involved in a wide range of physiologic and developmental events (Ooe et al., 2004 [PubMed 14701734]).[supplied by OMIM, Mar 2008].. Zusätzlich bieten wir Ihnen NPAS4 Proteine (6) und NPAS4 Kits (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
NPAS4 225872 Q8BGD7
NPAS4 266734 Q8CJH6
NPAS4 266743 Q8IUM7
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Top anti-NPAS4 Antikörper auf antikoerper-online.de

Showing 10 out of 106 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB Host: Rabbit Target Name: NPAS4 Sample Type: Fetal Lung Lane A: Primary Antibody Lane B: Primary Antibody + Blocking Peptide Primary Antibody Concentration: 1ug/ml Peptide Concentration: 5ug/ml Lysate Quantity: 25ug/lane/Lane Gel Concentration: 0.12 WB Suggested Anti-NPAS4 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Human Lung 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert IC, IF, IHC, WB Immunofluorescent analysis of NPAS4 staining in HEK293T cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a hidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of NPAS4 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Ziege Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Maus Kaninchen Unkonjugiert IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain tissue, using NPAS4 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Ziege Unkonjugiert ELISA, WB Western Blot: Npas4 Antibody [NBP1-68863] - NBP1-68863 (0.3ug/ml) staining of Human Frontal Cortex lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$485.88
Details
Human Ziege Unkonjugiert ELISA, WB 0.1 mg Anmelden zum Anzeigen 2 bis 3 Tage
$481.25
Details
Fledermaus Ziege Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$610.50
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Maus HRP ICC, IF, IHC, WB Western Blot analysis of Rat Brain showing detection of ~90 kDa NPAS4 protein using Mouse Anti-NPAS4 Monoclonal Antibody, Clone S408-79 . Lane 1: MW Ladder. Lane 2: Rat Brain. Load: 20 µg. Block: 2% GE Healthcare Blocker for 1 hour at RT. Primary Antibody: Mouse Anti-NPAS4 Monoclonal Antibody at 1:1000 for 16 hours at 4°C. Secondary Antibody: Goat Anti-Mouse IgG: HRP at 1:200 for 1 hour at RT. Color Development: ECL solution for 6 min at RT. Predicted/Observed Size: ~90 kDa. Other Band(s): ~60, 45, 40, 38, 25, 20 kDa. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$422.40
Details
Human Maus FITC ICC, IF, IHC, WB Western Blot analysis of Rat Brain showing detection of ~90 kDa NPAS4 protein using Mouse Anti-NPAS4 Monoclonal Antibody, Clone S408-79 . Lane 1: MW Ladder. Lane 2: Rat Brain. Load: 20 µg. Block: 2% GE Healthcare Blocker for 1 hour at RT. Primary Antibody: Mouse Anti-NPAS4 Monoclonal Antibody at 1:1000 for 16 hours at 4°C. Secondary Antibody: Goat Anti-Mouse IgG: HRP at 1:200 for 1 hour at RT. Color Development: ECL solution for 6 min at RT. Predicted/Observed Size: ~90 kDa. Other Band(s): ~60, 45, 40, 38, 25, 20 kDa. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$426.80
Details

Am meisten referenzierte anti-NPAS4 Antikörper

  1. Cow (Bovine) Polyclonal NPAS4 Primary Antibody für WB - ABIN2779719 : Ooe, Saito, Mikami, Nakatuka, Kaneko: Identification of a novel basic helix-loop-helix-PAS factor, NXF, reveals a Sim2 competitive, positive regulatory role in dendritic-cytoskeleton modulator drebrin gene expression. in Molecular and cellular biology 2003 (PubMed)
    Show all 2 Pubmed References

  2. Mouse (Murine) Polyclonal NPAS4 Primary Antibody für ICC, IF - ABIN4235495 : Wakasaya, Kawarabayashi, Watanabe, Yamamoto-Watanabe, Takamura, Kurata, Murakami, Abe, Yamada, Wakabayashi, Sasaki, Westaway, Hyslop, Matsubara, Shoji: Factors responsible for neurofibrillary tangles and neuronal cell losses in tauopathy. in Journal of neuroscience research 2011 (PubMed)

Weitere Antikörper gegen NPAS4 Interaktionspartner

Mouse (Murine) Neuronal PAS Domain Protein 4 (NPAS4) Interaktionspartner

  1. ectopic expression of miR (zeige MLXIP Antikörper)-744 and miR (zeige MLXIP Antikörper)-224 during neural differentiation resulted in downregulation of endogenous Npas4 expression.

  2. Using a series of behavioral, molecular, pharmacological and genetic approaches in mice, study shows that deficiency in Npas4 affects adolescent expression of multiple markers of GABAergic transmission in the PFC (zeige CFP Antikörper), including parvalbumin (zeige PVALB Antikörper) and GAD67 (zeige GAD1 Antikörper), in a sex-specific manner. Abnormal pattern of expression of GABAergic markers is associated with sex-specific and age-dependent cognitive and emotional impairments.

  3. The findings of this study suggest that Npas4 may be involved in post-stroke psychiatric changes related to anxiety ad sociability.

  4. NPAS4 is expressed in endothelial cells, regulates VE-cadherin (zeige CDH5 Antikörper) expression and regulates sprouting angiogenesis.

  5. These findings suggest that 11beta-HSD1 (zeige HSD11B1 Antikörper) may contribute to the decline in Npas4 and Arc (zeige NOL3 Antikörper) mRNA levels associated with memory impairment during ageing

  6. beta cell cytotoxicity of the calcineurin inhibitor (zeige RCAN1 Antikörper) and immunosuppressant tacrolimus (FK-506) was prevented by Npas4 overexpression.

  7. Results suggest that transcription of the Npas4 gene is downregulated by stress through DNA methylation (zeige HELLS Antikörper) of its promoter

  8. induction of Npas4 identifies the area influenced by cortical spreading depression propagation.

  9. Cortex activation by sensory conditioning was found to upregulate the expression of both Npas4 and c-Fos.

  10. Data showed that differential levels of Npas4 expression in the brain may regulate anxiety, depression and cognition related disorders.

Human Neuronal PAS Domain Protein 4 (NPAS4) Interaktionspartner

  1. NPAS4 is expressed in endothelial cells, regulates VE-cadherin (zeige CDH5 Antikörper) expression and regulates sprouting angiogenesis.

  2. This review summarizes the current knowledge of the roles that Npas4 may play in neuroinflammation and ischemia. [review]

  3. we provide the first evidence that Npas4 is expressed during embryonic development and that it may have a developmental role that is unrelated to its function in the adult brain

  4. These results provide insight into the mechanisms of NPAS4/ARNT (zeige ARNT Antikörper) dimerisation and transcriptional activation.

  5. a novel NXF signaling system on neural gene promoter may be a molecular target of the adverse effects of Sim2 (zeige SIM2 Antikörper) in the mental retardation of Down's syndrome

Zebrafish Neuronal PAS Domain Protein 4 (NPAS4) Interaktionspartner

  1. NPAS4 is expressed in endothelial cells, regulates VE-cadherin (zeige CDH5 Antikörper) expression and regulates sprouting angiogenesis.

NPAS4 Antigen-Profil

Protein Überblick

NXF is a member of the basic helix-loop-helix-PER (MIM 602260)-ARNT (MIM 126110)-SIM (see SIM2\; MIM 600892) (bHLH-PAS) class of transcriptional regulators, which are involved in a wide range of physiologic and developmental events (Ooe et al., 2004

Genbezeichner und Symbole assoziert mit NPAS4

  • neuronal PAS domain protein 4 (Npas4) Antikörper
  • neuronal PAS domain protein 4 (NPAS4) Antikörper
  • neuronal PAS domain protein 4a (npas4a) Antikörper
  • neuronal PAS domain protein 4 (npas4) Antikörper
  • neuronal PAS domain-containing protein 4 (Tsp_02837) Antikörper
  • bHLHe79 Antikörper
  • Le-PAS Antikörper
  • MGC146621 Antikörper
  • npas4 Antikörper
  • NXF Antikörper
  • PASD10 Antikörper
  • wu:fj52d04 Antikörper
  • zgc:136764 Antikörper

Bezeichner auf Proteinebene für NPAS4

HLH-PAS transcription factor NXF , bHLH-PAS type transcription factor NXF , limbic-enhanced PAS protein , neuronal PAS domain-containing protein 4 , neuronal PAS4 , bHLH PAS type transcription factor NXF , PAS domain-containing protein 10 , class E basic helix-loop-helix protein 79 , neuronal PAS domain protein 4 , neuronal PAS domain-containing protein 4-like

GENE ID SPEZIES
225872 Mus musculus
266734 Rattus norvegicus
266743 Homo sapiens
466676 Pan troglodytes
483711 Canis lupus familiaris
714161 Macaca mulatta
724016 Danio rerio
780368 Xenopus (Silurana) tropicalis
781497 Bos taurus
10899621 Trichinella spiralis
100029618 Monodelphis domestica
100052469 Equus caballus
100359105 Oryctolagus cuniculus
100397060 Callithrix jacchus
100442686 Pongo abelii
100481488 Ailuropoda melanoleuca
100520174 Sus scrofa
100593820 Nomascus leucogenys
100715310 Cavia porcellus
101113970 Ovis aries
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