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NXF is a member of the basic helix-loop-helix-PER (MIM 602260)-ARNT (MIM 126110)-SIM (see SIM2\; MIM 600892) (bHLH-PAS) class of transcriptional regulators, which are involved in a wide range of physiologic and developmental events (Ooe et al., 2004 [PubMed 14701734]).[supplied by OMIM, Mar 2008].. Zusätzlich bieten wir Ihnen NPAS4 Proteine (4) und NPAS4 Kits (3) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 75 products:
Human Polyclonal NPAS4 Primary Antibody für ELISA, WB - ABIN4340517
Ooe, Saito, Mikami, Nakatuka, Kaneko: Identification of a novel basic helix-loop-helix-PAS factor, NXF, reveals a Sim2 competitive, positive regulatory role in dendritic-cytoskeleton modulator drebrin gene expression. in Molecular and cellular biology 2003
Cow (Bovine) Polyclonal NPAS4 Primary Antibody für WB - ABIN2779719
Pruunsild, Sepp, Orav, Koppel, Timmusk: Identification of cis-elements and transcription factors regulating neuronal activity-dependent transcription of human BDNF gene. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2011
Show all 2 Pubmed References
Mouse (Murine) Polyclonal NPAS4 Primary Antibody für ICC, IF - ABIN4235495
Wakasaya, Kawarabayashi, Watanabe, Yamamoto-Watanabe, Takamura, Kurata, Murakami, Abe, Yamada, Wakabayashi, Sasaki, Westaway, Hyslop, Matsubara, Shoji: Factors responsible for neurofibrillary tangles and neuronal cell losses in tauopathy. in Journal of neuroscience research 2011
ectopic expression of miR (zeige MLXIP Antikörper)-744 and miR (zeige MLXIP Antikörper)-224 during neural differentiation resulted in downregulation of endogenous Npas4 expression.
Using a series of behavioral, molecular, pharmacological and genetic approaches in mice, study shows that deficiency in Npas4 affects adolescent expression of multiple markers of GABAergic transmission in the PFC (zeige CFP Antikörper), including parvalbumin (zeige PVALB Antikörper) and GAD67 (zeige GAD1 Antikörper), in a sex-specific manner. Abnormal pattern of expression of GABAergic markers is associated with sex-specific and age-dependent cognitive and emotional impairments.
The findings of this study suggest that Npas4 may be involved in post-stroke psychiatric changes related to anxiety ad sociability.
NPAS4 is expressed in endothelial cells, regulates VE-cadherin (zeige CDH5 Antikörper) expression and regulates sprouting angiogenesis.
These findings suggest that 11beta-HSD1 (zeige HSD11B1 Antikörper) may contribute to the decline in Npas4 and Arc (zeige NOL3 Antikörper) mRNA levels associated with memory impairment during ageing
beta cell cytotoxicity of the calcineurin inhibitor (zeige RCAN1 Antikörper) and immunosuppressant tacrolimus (FK-506) was prevented by Npas4 overexpression.
Results suggest that transcription of the Npas4 gene is downregulated by stress through DNA methylation (zeige HELLS Antikörper) of its promoter
induction of Npas4 identifies the area influenced by cortical spreading depression propagation.
Cortex activation by sensory conditioning was found to upregulate the expression of both Npas4 and c-Fos.
Data showed that differential levels of Npas4 expression in the brain may regulate anxiety, depression and cognition related disorders.
This review summarizes the current knowledge of the roles that Npas4 may play in neuroinflammation and ischemia. [review]
we provide the first evidence that Npas4 is expressed during embryonic development and that it may have a developmental role that is unrelated to its function in the adult brain
These results provide insight into the mechanisms of NPAS4/ARNT (zeige ARNT Antikörper) dimerisation and transcriptional activation.
a novel NXF signaling system on neural gene promoter may be a molecular target of the adverse effects of Sim2 (zeige SIM2 Antikörper) in the mental retardation of Down's syndrome
NXF is a member of the basic helix-loop-helix-PER (MIM 602260)-ARNT (MIM 126110)-SIM (see SIM2\; MIM 600892) (bHLH-PAS) class of transcriptional regulators, which are involved in a wide range of physiologic and developmental events (Ooe et al., 2004
HLH-PAS transcription factor NXF
, bHLH-PAS type transcription factor NXF
, limbic-enhanced PAS protein
, neuronal PAS domain-containing protein 4
, neuronal PAS4
, bHLH PAS type transcription factor NXF
, PAS domain-containing protein 10
, class E basic helix-loop-helix protein 79
, neuronal PAS domain protein 4
, neuronal PAS domain-containing protein 4-like