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NES encodes a member of the intermediate filament protein family and is expressed primarily in nerve cells. Zusätzlich bieten wir Ihnen Nestin Antikörper (323) und Nestin Proteine (7) und viele weitere Produktgruppen zu diesem Protein an.
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Knockdown of Nestin significantly reduced tumor volume in vivo.
Nestin plays an important role in the prediction of the clinicopathology and poor prognosis of glioma patients.
The authors found that high/positive SOX2 (zeige SOX2 ELISA Kits) alterations, either DNA amplification or protein expression, were favorable for overall survival (OS) in non-small cell lung cancer. On the contrary, high/positive Nestin protein expression was poor for OS.
Study clarified the relationship between Nestin overexpression and poor prognosis in recurrent human hepatocellular carcinoma (HCC) patients receiving FOLFOX regimen, and its association with chemoresistance and epithelial-mesenchymal transition in HCC cell lines.
Results show that the positive rates and expression levels of nestin, tyrosine hydroxylase (TH (zeige TH ELISA Kits)), GFAP (zeige GFAP ELISA Kits) and IL-17 (zeige IL17A ELISA Kits) were significantly decreased while Foxp3 (zeige FOXP3 ELISA Kits) and the ratio of Foxp3 (zeige FOXP3 ELISA Kits)/IL-17 (zeige IL17A ELISA Kits) were statistically elevated in BM of AML (zeige RUNX1 ELISA Kits) patients.
Nestin may have an important role in GIST malignancy by regulating mitochondrial dynamics and altering intracellular ROS (zeige ROS1 ELISA Kits) levels. The findings provide new clues to reveal mechanisms by which nestin mediates the proliferation and invasion of GISTs.
he present study reveals that nestin expression is a prognostic indicator of a poorer survival probability in NSCLC patients receiving adjuvant platinum-based chemotherapy , although its prognostic significance still requires confirmation with larger patient populations
Data suggest that negative feedback mediated by GLI3 (zeige GLI3 ELISA Kits) (GLI (zeige GLI1 ELISA Kits)-Kruppel family member) acts to finely tune SHH (sonic hedgehog (zeige SHH ELISA Kits)) signaling. During medulloblastoma (MB) formation, nerve tissue cells appear to express nestin which hyperactivates SHH (zeige SHH ELISA Kits) signaling by abolishing negative feedback by GLI3 (zeige GLI3 ELISA Kits). Restoration of intrinsic negative feedback by repressing nestin expression represents a promising approach to treat MB. [REVIEW]
the induction of P-gp (zeige ABCB4 ELISA Kits) expression is causally associated with the expression of nestin in leukemia cells
SRY (sex determining region Y)-box 10 (zeige SOX10 ELISA Kits) protein (SOX10 (zeige SOX10 ELISA Kits)) enhances nestin protein (NES) expression via directly binding to the promoter of NES.
Nestin promotesneural progenitor cells (NPCs) proliferation via p38-MAPK (zeige MAPK14 ELISA Kits) and EGFR (zeige EGFR ELISA Kits) pathways, and reveals the necessity of these pathways in NPCs self-renewal.
the loss of Nestin(+) cells might be an etiology to DCM pathogenesis, and these cells could be a promising candidate cell source for study and treatment of DCM patients
Nestin regulates neural stem cell migration via controlling the cell contractility
demonstrate that following postnatal ablation of granule cell progenitors, Nestin-expressing progenitors, specified during mid-embryogenesis to produce astroglia and interneurons, switch their fate and generate granule neurons in mice.
The nestin(+) cells contribute to all subsets of the complex stromal populations that can be found in lymph nodes.
nestin may label progenitor cells during inner ear development and may not be a stem cell marker in the mature organ of Corti
Nestin(+) cells are one important type of progenitor cell in bone marrow and are associated with bone remodeling. These data indicate that DMP1 (zeige DMP1 ELISA Kits) plays negative roles in differentiation of Nestin(+) cells and bone formation.
Our findings show how Nestin drives hedgehog (zeige SHH ELISA Kits) pathway-driven cancers and the tumor-promoting effects of Nestin were mediated by binding to Gli3 (zeige GLI3 ELISA Kits), a zinc finger transcription factor that negatively regulates hedgehog (zeige SHH ELISA Kits) signaling.
Based on a nestin-green fluorescent protein (NGFP) transgenic model, a histological inventory has been performed to deliver an overview of neuronal and glial markers for the various parts of the gastrointestinal tract in newborn (postnatal day 7) and adult mice under homeostatic conditions.
EGFR (zeige EGFR ELISA Kits) and Nestin showed to have vital role during mice development, and considered to be suitable markers for the study of skin stem cells.
Nestin gene may serve as a marker for stem cells and proliferating precursors in the developing embryonic nervous system as well as in the postembryonic brain[Nestin]
Results suggest that nestin is essential for brain and eye development probably through control of progenitor cell apoptosis.
Cells expressing the two reporters display radial glial morphology, colocalize with the NSC marker Sox2 (zeige SOX2 ELISA Kits), undergo proliferation, and are capable of self-renewal within the matrix of distinct thickness in the telencephalon.
This gene encodes a member of the intermediate filament protein family and is expressed primarily in nerve cells.
, intermediate filament protein