NK2 Homeobox 3 Proteine (NKX2-3)

NKX2-3 encodes a homeodomain-containing transcription factor. Zusätzlich bieten wir Ihnen NK2 Homeobox 3 Antikörper (16) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
NKX2-3 159296 Q8TAU0
NKX2-3 18089 P97334
Ratte NKX2-3 NKX2-3 309389  
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Showing 3 out of 4 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details

NKX2-3 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
,
Mouse (Murine)

Weitere Proteine zu NK2 Homeobox 3 (NKX2-3) Interaktionspartnern

Human NK2 Homeobox 3 (NKX2-3) Interaktionspartner

  1. NKX2-3 is a key mediator for maintaining myofibroblast characteristics, and our results show that colorectal myofibroblasts, as defined by the expression of AOC3 (zeige AOC2 Proteine), NKX2-3, and other markers, are a distinctly different cell type from TGFbeta (zeige TGFB1 Proteine)-activated fibroblasts

  2. The persons with a NKX2-3 G or T allele may have a moderately increased risk of CD.

  3. NKX2-3 may play different roles in ulcerative colitis and Crohn's disease pathogenesis by differential regulation of EGR1 (zeige EGR1 Proteine).

  4. A positive correlation was observed between mRNA expression of PTPN2 and NKX2-3 in B cells and in intestinal tissues from both Crohn's disease and ulcerative colitis patients.

  5. The binding of NFAT1 to the NKX2-3 promoter region with rs1190140 was confirmed by chromatin immunoprecipitation assay.

  6. the risk haplotype of NKX2.3 confers susceptibility to UC through increasing expression of NKX2.3 mRNA in the colonic mucosa.

  7. NKX2-3 may play an important role in inflammatory bowel disease pathogenesis by regulating endothelin-1 (zeige EDN1 Proteine) and VEGF (zeige VEGFA Proteine) signaling in human intestinal microvascular endothelial cells.

  8. Data suggest that NKX2-3 and IRGM (zeige IRGM Proteine) are susceptibility loci for inflammatory bowel disease in Eastern European patients.

  9. Nkx2-3 may contribute to the pathogenesis of inflammatory bowel disease-associated colorectal cancer and sporadic colorectal cancer by regulating the Wnt (zeige WNT2 Proteine) signaling pathway.

  10. a decrease in Nkx2-3 gene expression level can profoundly alter the expression of genes and cellular functions relevant to the pathogenesis and progression of inflammatory bowel disease, such as EDN1 (zeige EDN1 Proteine).

Mouse (Murine) NK2 Homeobox 3 (NKX2-3) Interaktionspartner

  1. Nkx2-3 deficiency reprograms the endothelial addressin preference for lymphocyte homing in Peyer's patches.

  2. the organ-specific patterning of splenic vasculature is critically regulated by Nkx2-3, thereby profoundly affecting the lymphocyte homing mechanism and blood filtering capacity of the spleen in a tissue-specific manner.

  3. The splenic vascular defects in Nkx2-3 deficiency include the generation of LYVE-1 (zeige LYVE1 Proteine)(+) cysts, comprised of endothelial cells without being committed along the LEC lineage.

  4. NKX2.3 has a role in mouse pharyngeal organogenesis

  5. Data indicate a substantial role for Nkx2-3 in the correct association of lymphocytes and splenic stromal elements that is independent of chemokine (zeige CCL1 Proteine) expression.

  6. Phenotypic heterogeneity among different vascular elements within distinct anatomical regions of the spleen differentially depends on developmental factors such as lymphotoxin (zeige LTB Proteine) signaling or Nkx2.3, whereas the marginal sinus is controlled by both pathways.

  7. Formation of various white pulp fibroblast subsets is differentially affected by the presence of Nkx2.3 activity, possibly also influencing their role in various immune functions linked with complement activation and deposition.

NK2 Homeobox 3 (NKX2-3) Protein Überblick

Protein Überblick

This gene encodes a homeodomain-containing transcription factor. The encoded protein is a member of the NKX family of homeodomain transcription factors. Studies of similar proteins in mouse and rat have indicated a potential role in cellular differentiation.

Genbezeichner und Symbole assoziert mit NK2 Homeobox 3 Proteine (NKX2-3)

  • NK2 homeobox 3 (NKX2-3)
  • NK2 homeobox 3 (Nkx2-3)
  • NK2 transcription factor related, locus 3 (NKX2-3)
  • CNKX-2.3 Protein
  • CSX3 Protein
  • NK2.3 Protein
  • Nkx-2.3 Protein
  • Nkx2.3 Protein
  • NKX2C Protein
  • NKX4-3 Protein
  • tinman Protein

Bezeichner auf Proteinebene für NK2 Homeobox 3 Proteine (NKX2-3)

NK2 transcription factor related, locus 3 , homeobox protein NK-2 homolog C , homeobox protein Nkx-2.3 , Drosophila NK2 transcription factor related, locus 3 , homeobox protein NK-2 homolog 3 , nkx2-C

GENE ID SPEZIES
159296 Homo sapiens
539451 Bos taurus
18089 Mus musculus
309389 Rattus norvegicus
395888 Gallus gallus
Ausgewählte Anbieter für NK2 Homeobox 3 Proteine (NKX2-3)
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