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The protein encoded by NDUFV3 is one of at least forty-one subunits that make up the NADH-ubiquinone oxidoreductase complex. Zusätzlich bieten wir Ihnen NADH Dehydrogenase (Ubiquinone) Flavoprotein 3, 10kDa Antikörper (34) und und viele weitere Produktgruppen zu diesem Protein an.
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NDUFV3 represents the first known complex I subunit present in two functional isoforms.
The results provide new information on the function of the region affected by the MELAS mutations 3946 and 3949 that is not obtainable from patient samples or current eukaryote models.
Further mass spectrometric analyses of complex I from different murine and bovine tissues showed a tissue-specific expression pattern of NDUFV3-S and NDUFV3-L. Hence, NDUFV3-S was identified as the only isoform in heart and skeletal muscle, whereas in liver, brain, and lung NDUFV3-L was expressed as the dominant isoform, together with NDUFV3-S present in all tissues analyzed
The protein encoded by this gene is one of at least forty-one subunits that make up the NADH-ubiquinone oxidoreductase complex. This complex is part of the mitochondrial respiratory chain and serves to catalyze the rotenone-sensitive oxidation of NADH and the reduction of ubiquinone. The encoded protein is one of three proteins found in the flavoprotein fraction of the complex. The specific function of the encoded protein is unknown. Two transcript variants encoding different isoforms have been found for this gene.
NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial
, NADH-ubiquinone oxidoreductase 9 kD subunit
, NADH-ubiquinone oxidoreductase 9 kDa subunit
, NADH-ubiquinone oxidoreductase flavoprotein 3, 10kD
, complex I 10kDa subunit
, complex I, mitochondrial respiratory chain, 10-kD subunit
, complex I-9kD
, mitochondrial NADH oxidoreductase-like protein
, renal carcinoma antigen NY-REN-4
, NADH dehydrogenase (ubiquinone) flavoprotein 3-like
, NADH-ubiquinone oxidoreductase flavoprotein 3
, mitochondrial complex I subunit NDUFV3
, NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa