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NAT1 is one of two arylamine N-acetyltransferase (NAT) genes in the human genome, and is orthologous to the mouse and rat Nat2 genes. Zusätzlich bieten wir Ihnen NAT1 Kits (8) und und viele weitere Produktgruppen zu diesem Protein an.
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identified a novel endogenous role for human NAT1 (zeige EIF4G2 Antikörper) that might explain some of its effects in cancer cell growth and survival
N-acetyltransferase polymorphisms are associated with risk of lymphoma subtypes.
The association of colorectal adenomas with the rs6983267 variant at 8q24 was considered as 'highly credible', the 'less credible' associations were identified with a further four variants of four independent genes: MTHFR (zeige MTHFR Antikörper) c.677C>T p.A222V(rs1801133), TP53 (zeige TP53 Antikörper) c.215C>G p.R72P (rs1042522), NQO1 (zeige NQO1 Antikörper) c.559C>T p.P187S (rs1800566), and NAT1 (zeige EIF4G2 Antikörper) alleles imputed as fast acetylator genotypes. [meta-analysis]
NAT1 (zeige EIF4G2 Antikörper) genotype affects thioguanine nucleotide levels in patients treated with thiopurines and aminosalicylates and could therefore influence the toxicity and efficacy of these drugs.
NAT1 (zeige EIF4G2 Antikörper) genetic polymorphisms were found to be a risk factor for smokers in the Black population of South Africa with esophageal squamous cell carcinoma.
NAT1 (zeige EIF4G2 Antikörper) has a role in the metabolic pathway of nicotine/cotinine and/or their metabolites.
We report that miR (zeige MLXIP Antikörper)-1290 directly targets the NAT1 (zeige EIF4G2 Antikörper) 3'-UTR (zeige UTS2R Antikörper) and that NAT1 (zeige EIF4G2 Antikörper) protein expression is correlated with improved OS of breast cancer patients.
Arylamine N-acetyltransferase polymorphisms in Han Chinese patients with ankylosing spondylitis and their correlation to the adverse drug reactions to sulfasalazine
Candidate gene NAT1 (zeige EIF4G2 Antikörper) were elevated in male breast cancer biopsies compared to those from female patients without regard to Estrogen Receptors status.
Data suggest that NAT1 (zeige EIF4G2 Antikörper)/NAT2 (zeige SLC38A1 Antikörper) participate in biotransformation of many aromatic/heterocyclic amines; molecular models have been developed regarding acetylation mechanism, active site structure, and substrate/inhibitor-binding specificity. [REVIEW]
This gene is one of two arylamine N-acetyltransferase (NAT) genes in the human genome, and is orthologous to the mouse and rat Nat2 genes. The enzyme encoded by this gene catalyzes the transfer of an acetyl group from acetyl-CoA to various arylamine and hydrazine substrates. This enzyme helps metabolize drugs and other xenobiotics, and functions in folate catabolism. Multiple transcript variants encoding different isoforms have been found for this gene.
, N-acetyltransferase (arylamine N-acetyltransferase)
, N-acetyltransferase 1 (arylamine N-acetyltransferase)
, N-acetyltransferase type 1
, arylamide acetylase 1
, arylamine N-acetyltransferase 1
, monomorphic arylamine N-acetyltransferase