Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) Proteine (MMP3)

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Zusätzlich bieten wir Ihnen Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) Antikörper (376) und Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) Kits (163) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
MMP3 4314 P08254
MMP3 17392 P28862
MMP3 171045  
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Top Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) Proteine auf antikoerper-online.de

Showing 10 out of 54 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,749.58
Details
Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$5,370.21
Details
HEK-293 Cells Maus Unkonjugiert   10 μg Anmelden zum Anzeigen 10 bis 12 Tage
$222.28
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HEK-293 Cells Human Unkonjugiert   10 μg Anmelden zum Anzeigen 10 bis 12 Tage
$222.28
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Escherichia coli (E. coli) Human Unkonjugiert 10 μg Anmelden zum Anzeigen 6 bis 7 Tage
$474.41
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Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$717.00
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Human Cells Human His tag   50 μg Anmelden zum Anzeigen 4 Days
$522.50
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Escherichia coli (E. coli) Human Unkonjugiert Validation with Western Blot 10 μg Anmelden zum Anzeigen 4 bis 8 Tage
$218.90
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Escherichia coli (E. coli) Ratte His tag,T7 tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$640.00
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Escherichia coli (E. coli) Maus His tag,T7 tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$733.00
Details

MMP3 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , ,
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Mouse (Murine) ,
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Rat (Rattus) ,
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Weitere Proteine zu Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) Interaktionspartnern

Human Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) Interaktionspartner

  1. MMP3 (rs591058) gene polymorphism is associated with lumbar disc degeneration among women, and the TT genotype confers a lower risk of LDD.

  2. BMAL1 Deficiency Contributes to Mandibular Dysplasia by Upregulating MMP3.

  3. No significant associations were observed with either MMP-2(-1306) C/T or MMP-3(-1171) 5A/6A.

  4. rs3025058 in MMP3 and rs2276109 in MMP12 might not contribute to the risk of developing rheumatic heart disease in a Han population in Southern China.

  5. study to explore the relationship between 2 polymorphisms (MMP-1-755 T/G [rs498186] and MMP-3 A/C [rs632478]) and disc degeneration; a significant association was found between the MMP-3 polymorphism and disc degeneration; the homozygote CC was associated with an increased risk of disc degeneration compared with the AA genotype

  6. Higher serum MMP-3 levels in knee osteoarthritis reflect disease "generalization".

  7. Report a positive correlation between glomerular filtration rate and MMP-3 activity in diabetic patients.

  8. The maternal and fetal MMP3 gene polymorphisms may be strong genetic markers of preeclampsia, occurring either individually or together.

  9. 2G allele of MMP-1, C allele of MMP-2 and 5A/6A genotype of MMP-3 are associated with susceptibility and disease progression of type 2 diabetic nephropathy

  10. MMP-1 genotype may accelerate the development of HIV-associated neurocognitive disorder (HAND) whereas MMP3 -1612 5A5A genotype may reduce the risk of pathogenesis of HAND.

  11. Preliminary studies indicate that baseline MMP3 and TIMP3 concentrations are associated with patient survival and disease-free time

  12. MMP-3 (Lys45Glu) polymorphisms associate with obesity risk and its severity.

  13. Data suggest that serum matrix metalloproteinase-3 (MMP-3) and the 7-joint ultrasound score (US7) scores could both effectively reflect disease activity and therapeutic responses in patients with moderate to severe rheumatoid arthritis (RA).

  14. results demonstrated that measurement of MMP-3 could become a marker of disease activity in rheumatoid arthritis patients

  15. The results indicated that the 5A allele of the MMP3 gene-promoter region could be associated with oral submucous fibrosis risk factor, but not oral squamous cell carcinoma, in an Indian population

  16. C/EBPbeta upregulation promoted tumor cell invasion in an MMP3-dependent manner in vitro and was associated with metastatic status in colorectal cancer

  17. MMP3 (and MMP-1 and MMP-2) are independently associated with markers of arterial stiffening in patients with type 1 diabetes.

  18. None of the studied polymorphisms showed statistically significant association with the risk of varicose veins of the lower extremities.

  19. A significant increase in the frequency of the MMP3-1171dupA (rs3025058) polymorphism genotype among patients with unstable angina was detected.

  20. No interaction between MMP-3 5A/6A polymorphism and the risk of recurrence in total IS patients was found. The variant 5A/6A+5A/5A genotype and the 5A allele were significantly associated with a high risk of recurrence for large-artery atherosclerosis (LAA) (multivariate-adjusted, P=0.002, 0.001, respectively), but not for small-artery occlusion and cardioembolism.

Mouse (Murine) Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) Interaktionspartner

  1. that the impact of MMP3 on neuronal morphology may be regionspecific

  2. BMAL1 Deficiency Contributes to Mandibular Dysplasia by Upregulating MMP3.

  3. Estrogen-related receptor gamma (ERRgamma) overexpression in chondrocytes directly upregulates matrix metalloproteinase (MMP)-3 and MMP13, which are known to play crucial roles in cartilage destruction in osteoarthritis (OA).

  4. MMP3 contributes to the pathogenesis of ARDS by affecting the pulmonary inflammatory response in female mice in relevant models of lung injury.

  5. endogenously secreted chemerin plays an autocrine/paracrine role in white adipose tissue, identifying chemerin as a therapeutic target to modulate adipose remodelling.

  6. Overexpression of Mmp3 in 3T3-L1 preadipocytes inhibited differentiation. High fat diet-induced obesity downregulates adipocyte MMP3 expression to trigger adipogenesis, and adipocyte TIMP4 may modulate this process to regulate hyperplastic vs. hypertrophic adipose tissue expansion, fat distribution, and metabolic health in a sex- and depot-dependent manner.

  7. Matrix metalloprotease 3 (MMP3), an endogenous neuronal activator of microglia, increased cytokine release from YAC128 microglia compared to wildtype microglia. We found elevated MMP levels in Huntington's Disease (HD) CSF, and MMP levels correlate with disease severity in HD. These data support a novel role for MMPs and microglial activation in HD pathogenesis.

  8. These results indicate that periodic induction, via use of an eye drop, of AAV-mediated secretion of MMP-3 into aqueous humour could have therapeutic potential for those cases of glaucoma that are sub-optimally responsive to conventional pressure-reducing medications.

  9. Data show that loss of loss of matrix metalloproteinase-3 (MMP-3) repressed the upregulation of the chemokines monocyte chemoattractant protein (MCP)-1 and (C-X-C motif) ligand 1 (CXCL1).

  10. Mmp3-knockout mice maintained higher arterial oxygenation compared to wild-type mice in a model of acute lung injury.

  11. NMP4 deficiency suppressed the arthritis-induced increase in bone resorption, expression of RANKL and MMP-3 mRNA.

  12. MMP-3 produced in blood vessel endothelial cells after spinal cord injury serves as an endogenous molecule for microglial activation followed by p38MAPK activation and proNGF production

  13. genetic inactivation of MMP-3 has profound effects on the structural integrity and plasticity response of the visual cortex of adult mice

  14. study found significant increases of MMP-3 and MMP-12 mRNA levels and MMP12 zymographic activities in response to Cryptococcus neoformans infection but not C. gattii infection

  15. This study demonstrates the sequential involvement of Wnt5, MMP-3, DMP-1 expression, and DMP-1 degradation products by MMP-3, in effecting IL-1beta-induced proliferation of ESC-derived odontoblast-like cells.

  16. Study suggests that MMP-3 modulates intracellular MAP kinase signaling pathway and as such, influences a molecular chaperone that regulates cytoskeletal components important for neurite outgrowth, neuronal migration and dendritic arborization

  17. Data indicate that interferon regulatory factor-8 (IRF8) regulates tumor behavior in an matrix metalloproteinase 3 (MMP3)-dependent manner.

  18. Established are novel molecular mechanisms underlying oxidative stress-mediated dopaminergic neuronal death in which MMP3 activation is a key upstream event that leads to Nox1 induction and eventual dopaminergic neuronal death.

  19. Our findings suggest that increased numbers of CD11c(+) macrophages and elevated levels of TNF-alpha and MMP-3 in AT and ST may explain the relationship between hyperlipidaemia and OA.

  20. These results demonstrated the role of MMP-3 in blood-spinal cord disruption after spinal cord injury for the first time

Pig (Porcine) Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) Interaktionspartner

  1. The present study was aimed to determine the association between metalloproteinase 3 (MMP3), transforming growth factor beta 1 (TGFbeta1) and collagen type X alpha I (COL10A1) gene polymorphisms with traits related to leg weakness in pigs.

  2. the identification of MMP1 and MMP10 genes in swine is reported.

  3. contribution of MMPs to the inflammatory breakdown of the blood-CSF barrier in vitro

  4. Results indicate that leukemia inhibitory factor (LIF) and Oncostatin M increase the expression of MMP-1, MMP-3, and TIMP-1 several fold, and that their expression is reduced to basal levels in the presence of the LIF antagonist MH35-BD.

Rabbit Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) Interaktionspartner

  1. Compromised autophagy may be related to the osteoarthritis progression; JNK and p38 MAPKs up-regulate MMP3 and down-regulate autophagy.

  2. the total content and active forms of matrix metalloproteinases (MMPs)-1, -3, and -13 was measured to assess the potential role of the mechanical environment in regulation of matrix turnover by ligament fibroblasts.

  3. chitosan-pDNA nanoparticles encoding shRNA targeting MMP-3 and -13 had great potential in silencing the dedifferentiation-related genes for regenerating prolonged and endurable cartilage.

  4. Ulinastatin effectively inhibited the increased expression of MMP-2, MMP-3, and iNOS in degenerated NP cells induced by IL-1beta in vitro.

  5. Exposure to long periods of light irrespective of its characteristics leads to the increased expression of some matrix metalloprpteases.

  6. Tongxinluo can inhibit the expression of MMP-3 and 9 and increase the expression of PPARgamma in atherosclerotic rabbits.

Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) Protein Überblick

Protein Überblick

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

Genbezeichner und Symbole assoziert mit MMP3

  • matrix metallopeptidase 3 (MMP3)
  • matrix metallopeptidase 3 (Mmp3)
  • matrix metallopeptidase 3 (stromelysin 1, progelatinase) (MMP3)
  • matrix metallopeptidase 3 L homeolog (mmp3.L)
  • chds6 Protein
  • mmp-3 Protein
  • mmp3 Protein
  • MMP10 Protein
  • mmp13 Protein
  • sl-1 Protein
  • SLN-1 Protein
  • SLN1 Protein
  • stmy Protein
  • stmy1 Protein
  • STR-1 Protein
  • str1 Protein

Bezeichner auf Proteinebene für MMP3

matrix metalloproteinase 3 (stromelysin 1, progelatinase) , matrix metalloproteinase-3 , proteoglycanase , stromelysin-1 , transin-1 , EMS-2 , MMP-3 , SL-1 , matrix metalloproteinase 3 , progelatinase , stromelysin 1 , PTR1 protein , stromelysin , metalloproteinase 3 receptor , matrix metallopeptidase 3 (stromelysin 1, progelatinase) , matrix metallopeptidase 3 L homeolog , matrix metalloproteinase 13 (collagenase 3)

GENE ID SPEZIES
4314 Homo sapiens
17392 Mus musculus
171045 Rattus norvegicus
396769 Sus scrofa
100009111 Oryctolagus cuniculus
100034195 Equus caballus
403445 Canis lupus familiaris
281309 Bos taurus
101118895 Ovis aries
446898 Xenopus laevis
Ausgewählte Anbieter für Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) Proteine (MMP3)
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