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Microtubule-associated protein that exhibits cell cycle- dependent localization and can inhibit cell proliferation and migration (By similarity).. Zusätzlich bieten wir Ihnen MARVELD1 Antikörper (14) und viele weitere Produktgruppen zu diesem Protein an.
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MARVELD1 mediated the invasion of trophoblast cells via regulation of the expression of integrin beta4 during placenta development.
MARVELD1 is a microtubule-associated protein (zeige SPAG5 Proteine) that plays an important role in cell cycle progression and migration
MARVELD1 substantially inhibits nonsense-mediated RNA decay by decreasing the pioneer round of translation but not steady-state translation, and is an important component of the molecular machinery containing UPF1 (zeige UPF1 Proteine) and Y14 (zeige RBM8A Proteine). MARVELD1 promotes the dissociation of SMG1 from UPF1 (zeige UPF1 Proteine), resulting in the repression of serine phosphorylation of UPF1 (zeige UPF1 Proteine), and subsequently blocks the recruitment of SMG5 (zeige SMG5 Proteine).
Study demonstrates that MARVELD1-mediated balance of integrin beta1 and beta4 regulates cell surface ultrastructure and epithelial-mesenchymal transition phenotype of non-small cell lung cancer (NSCLC).
MARVELD1 silencing is an appealing diagnostic biomarker for lung cancer.
Importin-beta1 mediates the non-classical nucleocytoplasmic transport of MARVELD1.
MARVELD1 plays a role in pre-mRNA processing of integrin beta1.
Our findings suggest that MARVELD1 is a tumor suppressor by negatively regulating proliferation, tumor growth and chemosensitivity of HCC cells via increasing p53 and p16 in vitro and in vivo.
MARVELD1 protein is located in nucleus instead of cell membrane in several different tumors, in males and in females.
Microtubule-associated protein that exhibits cell cycle- dependent localization and can inhibit cell proliferation and migration (By similarity).
MARVEL (membrane-associating) domain containing 1
, MARVEL domain-containing protein 1
, putative MARVEL domain-containing protein 1