anti-Lysine (K)-Specific Demethylase 4A (KDM4A) Antikörper

KDM4A is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. Zusätzlich bieten wir Ihnen KDM4A Kits (5) und KDM4A Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
KDM4A 9682 O75164
KDM4A 230674 Q8BW72
KDM4A 313539  
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Top anti-KDM4A Antikörper auf antikoerper-online.de

Showing 10 out of 125 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert ChIP, ICC, IF, IP, WB Western Blot: Lysine (K)-specific Demethylase 4A/KDM4A/JMJD2A Antibody [ABIN43320645] - Detection of Human and Mouse Lysine (K)-specific Demethylase 4A/KDM4A/JMJD2A on HeLa whole cell lysate using ABIN43320645. Lysine (K)-specific Demethylase 4A/KDM4A/JMJD2A was also immunoprecipitated by rabbit anti-Lysine (K)-specific Demethylase 4A/KDM4A/JMJD2A antibody ABIN43320644. Western Blot: Lysine (K)-specific Demethylase 4A/KDM4A/JMJD2A Antibody  - Nuclear extract (50 ug) from HeLa, 293T, and mouse NIH3T3 cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-JMJD2A antibody used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$556.31
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: Lysine (K)-specific Demethylase 4A/KDM4A/JMJD2A Antibody [NBP1-87855] - Staining of human testis shows strong cytoplasmic positivity in cells in seminiferus ducts. Western Blot: Lysine (K)-specific Demethylase 4A/KDM4A/JMJD2A Antibody [NBP1-87855] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details
Human Kaninchen Unkonjugiert ELISA, WB 25 μg Anmelden zum Anzeigen 2 bis 3 Tage
$185.00
Details
Human Kaninchen Unkonjugiert ICC, IHC, WB Western Blot; Sample: Mouse Cerebrum lysate; Primary Ab: 2µg/ml Rabbit Anti-Human KDM4A Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) 100 μg Anmelden zum Anzeigen 13 bis 16 Tage
$350.00
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of JMJD2A(arrow) using rabbit polyclonal JMJD2A (N-term)(ABIN387900). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the JMJD2A gene (Lane 2) (Origene Technologies). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
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Human Kaninchen Unkonjugiert EIA, WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert IHC (p), ELISA, WB Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$484.00
Details
Human Kaninchen Unkonjugiert DB Dot blot analysis of anti-Phospho-JMJD2A-Y547 Phospho-specific Pab (ABIN650862) on nitrocellulose membrane.  50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5 µg/mL. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Maus Unkonjugiert ICC, IHC, ELISA, WB Figure 1: Immunofluorescence analysis of NTERA-2 cells using KDM4A mouse mAb (green) . Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin. Figure 2: Immunohistochemical analysis of paraffin-embedded colon cancer tissues (left) and human larynx cancer tissues (right) using KDM4A mouse mAb with DAB staining. 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$393.80
Details
Human Kaninchen Unkonjugiert WB Western Blot: Lysine (K)-specific Demethylase 4A/KDM4A/JMJD2A Antibody  - Sample (30 ug of whole cell lysate) A: Raji 7.5% SDS PAGE diluted at 1:1000 0.1 mL Anmelden zum Anzeigen 8 bis 11 Tage
$514.63
Details

KDM4A Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Rat (Rattus)


Am meisten referenzierte anti-KDM4A Antikörper

  1. Human Polyclonal KDM4A Primary Antibody für ChIP, ICC - ABIN4332064 : Shin, Janknecht: Activation of androgen receptor by histone demethylases JMJD2A and JMJD2D. in Biochemical and biophysical research communications 2007 (PubMed)
    Show all 11 Pubmed References

  2. Mammalian Monoclonal KDM4A Primary Antibody für ISt, IHC - ABIN1304721 : Black, Allen, Van Rechem, Forbes, Longworth, Tschöp, Rinehart, Quiton, Walsh, Smallwood, Dyson, Whetstine: Conserved antagonism between JMJD2A/KDM4A and HP1? during cell cycle progression. in Molecular cell 2010 (PubMed)
    Show all 3 Pubmed References

  3. Human Monoclonal KDM4A Primary Antibody für ICC, IHC - ABIN969230 : Suzuki, Yamashita, Shirota, Sakakibara, Chiba, Mizushima-Sugano, Nakai, Sugano: Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. in Genome research 2004 (PubMed)
    Show all 3 Pubmed References

  4. Human Polyclonal KDM4A Primary Antibody für ICC, IF - ABIN4332072 : Verrier, Escaffit, Chailleux, Trouche, Vandromme: A new isoform of the histone demethylase JMJD2A/KDM4A is required for skeletal muscle differentiation. in PLoS genetics 2011 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen KDM4A Interaktionspartner

Human Lysine (K)-Specific Demethylase 4A (KDM4A) Interaktionspartner

  1. JMJD2A regulated aerobic glycolysis by regulating LDHA (zeige LDHA Antikörper) expression. Therefore, the novel JMJD2A-LDHA (zeige LDHA Antikörper) signaling pathway could contribute to the Warburg effects in NPC (zeige NPC1 Antikörper) progression.

  2. These results reveal KDM4A as a key epigenetic silencer of TRAIL and DR5 (zeige TNFRSF10B Antikörper) in tumors.

  3. Findings inidicate a unique breast cancer stem-like cells (BCSC) culture system for drug screening and offer preclinical proof of concept for lysine demethylase (zeige MBD2 Antikörper) 4A (KDM4A) inhibition as a new strategy to treat triple-negative breast cancer.

  4. The pyruvate dehydrogenase (zeige PDP Antikörper) kinases (PDKs) PDK1 (zeige PDK1 Antikörper) and PDK3 (zeige PDK3 Antikörper) are direct targets of KDM4A and E2F1 (zeige E2F1 Antikörper) and modulate the switch between glycolytic metabolism and mitochondrial oxidation.

  5. results suggest that KDM4A possesses the potential to act as an oxygen sensor in the context of chromatin modifications, with possible implications for epigenetic regulation in hypoxic disease states

  6. Here we show that JMJD2A, the first identified Jumonji (zeige JARID2 Antikörper) C domain-containing histone demethylase (zeige MBD2 Antikörper), is the histone demethylase (zeige MBD2 Antikörper) responsible for SUMO-2 (zeige SUMO2 Antikörper)/3 enrichment on the Kaposi's sarcoma associated herpesvirus genome during viral reactivation

  7. Lgr4 activates Jmjd2a/AR signaling pathway to promote interaction AR with PSA promoter, causing reduction of prostate cancer apoptosis and cell cycle arrest.

  8. We demonstrate the previously unreported inhibitory action of PKF118-310 on KDM4A. Our findings open up the possibility of developing the first KDM4A-specific inhibitors and derivatives.

  9. KDM4A downregulation promotes autophagy in glioma cell lines.

  10. ERG (zeige ERG Antikörper) promotes prostate tumorigenesis together with KDM4A through the upregulation of YAP1 (zeige YAP1 Antikörper). A corollary is that KDM4A as well as YAP1 (zeige YAP1 Antikörper) inhibitors may prove beneficial for the therapy of ERG (zeige ERG Antikörper)-overexpressing prostate tumors.

Mouse (Murine) Lysine (K)-Specific Demethylase 4A (KDM4A) Interaktionspartner

  1. Jmjd2 class demethylases are critical epigenetic regulators involved in etiopathology of depression and related disorders.

  2. High Jmjd2a expression is associated with neuropathic pain.

  3. This study dissects an important dual role for maternal Kdm4a in determining faithful early embryonic development and the implantation process.

  4. We propose the inhibition of KDM4A activity as a strategy to suppress IL-6 (zeige IL6 Antikörper) production and attenuate colitis induction.

  5. The authors show that Jmjd2a and Jmjd2c (zeige KDM4C Antikörper) both localize to H3K4me3-positive promoters, where they have widespread and redundant roles in preventing accumulation of H3K9me3 and H3K36me3.

  6. these data reveal a JMJD2A/ETV1 (zeige ETV1 Antikörper)/YAP1 (zeige YAP1 Antikörper) axis that promotes prostate cancer initiation and that may be a suitable target for therapeutic inhibition.

  7. Results indicate that SCF (zeige KITLG Antikörper)(Fbxo22 (zeige FBXO22 Antikörper))-KDM4A is an E3 ubiquitin ligase (zeige MUL1 Antikörper) that targets methylated p53 (zeige TP53 Antikörper) and regulates key senescent processes.

  8. These findings together demonstrate the essential role of KDM4A and KDM4C (zeige KDM4C Antikörper) in orchestrating mESC differentiation to endothelial cells through the activation of Flk1 (zeige KDR Antikörper) and VE-cadherin (zeige CDH5 Antikörper) promoters, respectively

  9. As well as three novel motifs in JMJD2A-regulated genes.

  10. JMJD2A bound to the FHL1 (zeige FHL1 Antikörper) promoter in response to TAC (zeige IL2RA Antikörper), upregulated FHL1 (zeige FHL1 Antikörper) expression, and downregulated H3K9 trimethylation. JMJD2A promotes cardiac hypertrophy under pathological conditions by a novel mechanism.

Cow (Bovine) Lysine (K)-Specific Demethylase 4A (KDM4A) Interaktionspartner

  1. Histone demethylases KDM3A (zeige KDM3A Antikörper), KDM4A, and KDM4C (zeige KDM4C Antikörper) were expressed before and after embryonic genome activation, whereas KDM5B (zeige KDM5B Antikörper) was mainly expressed during the blastocyst period.

KDM4A Antigen-Profil

Protein Überblick

This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor.

Genbezeichner und Symbole assoziert mit KDM4A

  • lysine demethylase 4A (KDM4A) Antikörper
  • lysine-specific demethylase 4A (LOC100228023) Antikörper
  • lysine (K)-specific demethylase 4A (KDM4A) Antikörper
  • lysine (K)-specific demethylase 4A (Kdm4a) Antikörper
  • lysine demethylase 4A (Kdm4a) Antikörper
  • D4Ertd222e Antikörper
  • JHDM3A Antikörper
  • Jmjd2 Antikörper
  • Jmjd2a Antikörper
  • mKIAA0677 Antikörper
  • TDRD14A Antikörper

Bezeichner auf Proteinebene für KDM4A

jumonji domain containing 2A , lysine (K)-specific demethylase 4A , lysine-specific demethylase 4A , jumonji domain-containing protein 2A , JmjC domain-containing histone demethylation protein 3A , jumonji domain-containing 2A , lysine-specific demethylase 4A-like , jmjC domain-containing histone demethylation protein 3A , jumonji C domain-containing histone demethylase 3A , jumonji domain containing 2 , tudor domain containing 14A

GENE ID SPEZIES
424571 Gallus gallus
456829 Pan troglodytes
701272 Macaca mulatta
100172003 Pongo abelii
100353935 Oryctolagus cuniculus
100228023 Taeniopygia guttata
100294710 Sus scrofa
100473204 Ailuropoda melanoleuca
100544296 Meleagris gallopavo
9682 Homo sapiens
230674 Mus musculus
313539 Rattus norvegicus
482530 Canis lupus familiaris
512622 Bos taurus
Ausgewählte Anbieter für anti-KDM4A (KDM4A) Antikörper
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