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The protein encoded by LAIR1 is an inhibitory receptor found on peripheral mononuclear cells, including NK cells, T cells, and B cells. Zusätzlich bieten wir Ihnen LAIR1 Proteine (29) und LAIR1 Kits (16) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 223 products:
Human Monoclonal LAIR1 Primary Antibody für FACS, IP - ABIN1690739
Poggi, Tomasello, Ferrero, Zocchi, Moretta: p40/LAIR-1 regulates the differentiation of peripheral blood precursors to dendritic cells induced by granulocyte-monocyte colony-stimulating factor. in European journal of immunology 1998
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Human Monoclonal LAIR1 Primary Antibody für FACS, IP - ABIN1690731
Poggi, Tomasello, Revello, Nanni, Costa, Moretta: p40 molecule regulates NK cell activation mediated by NK receptors for HLA class I antigens and TCR-mediated triggering of T lymphocytes. in International immunology 1997
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Human Monoclonal LAIR1 Primary Antibody für FACS - ABIN4896415
Rodríguez-Bayona, Ramos-Amaya, Brieva: Differential expression of SLAMS and other modulatory molecules by human plasma cells during normal maturation. in Immunology letters 2010
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Human Monoclonal LAIR1 Primary Antibody für FACS - ABIN2689802
Xu, Zhao, Zhao: Identification and characterization of leukocyte-associated Ig-like receptor-1 as a major anchor protein of tyrosine phosphatase SHP-1 in hematopoietic cells. in The Journal of biological chemistry 2000
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Human Monoclonal LAIR1 Primary Antibody für FACS, IP - ABIN2479896
Leopold, Charleux: [Continuous corneal suture]. in Bulletin des sociétés d'ophtalmologie de France 1976
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Human Monoclonal LAIR1 Primary Antibody für FACS - ABIN2479899
Poggi, Pella, Morelli, Spada, Revello, Sivori, Augugliaro, Moretta, Moretta: p40, a novel surface molecule involved in the regulation of the non-major histocompatibility complex-restricted cytolytic activity in humans. in European journal of immunology 1995
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Human Polyclonal LAIR1 Primary Antibody für ELISA, WB - ABIN4229006
Tang, Narayanan, Peruzzi, Apara, Natarajan, Margulies, Coligan, Borrego: A single residue, arginine 65, is critical for the functional interaction of leukocyte-associated inhibitory receptor-1 with collagens. in Journal of immunology (Baltimore, Md. : 1950) 2009
Human Monoclonal LAIR1 Primary Antibody für CyTOF, FACS - ABIN4899640
Cabezón, Sintes, Llinàs, Benitez-Ribas: Analysis of HLDA9 mAbs on plasmacytoid dendritic cells. in Immunology letters 2010
these data demonstrate that collagen can suppress the T cell cytokine response through the action of LAIR-1, and that LAIR-1-/- mice develop more severe arthritis
LAIR-1 in megakaryocytes leads to increased Src (zeige SRC Antikörper) family kinase activity and downstream signaling in response to collagen that is transmitted to platelets, rendering them hyper-reactive specifically to agonists that signal through Syk (zeige SYK Antikörper) tyrosine kinases.
The LAIR1-SHP-1 (zeige PTPN6 Antikörper)-CAMK1 (zeige CAMK1 Antikörper)-CREB (zeige CREB1 Antikörper) pathway sustains the survival and self-renewal of AML (zeige RUNX1 Antikörper) stem cells.
LAIR-1-deficient mice are healthy and fertile with normal longevity, showing increased numbers of splenic B, regulatory T, and dendritic cells.
tumor-expressed collagens can bind and trigger immune inhibitory signaling via LAIR-1, suggesting that collagens indeed may affect tumor immune evasion.
Mouse Lair-1 cytoplasmic tail can become phosphorylated, thereby recruiting SH2 (zeige MYO15 Antikörper)-containing tyrosine phosphatase-2 (SHP-2 (zeige PTPN11 Antikörper)). Unlike human LAIR-1, SHP-1 (zeige PTPN6 Antikörper) is not recruited to the mouse Lair-1 cytoplasmic tail.
analysis of leukocyte Ig-like receptor (zeige LILRA6 Antikörper) signaling and crystal structure of disulfide-linked HLA-G (zeige HLAG Antikörper) dimer
findings show that mLAIR-1 interacted with high affinity with a wide range of collagen molecules; mLAIR-1 cross-linking with its ligands inhibits CD3 (zeige CD3E Antikörper)-induced T cell stimulation in vitro
LAIR1 is used for immune evasion of Plasmodium falciparum by associating with RIFIN.
We suggest that LAIR1 and LAIR2 (zeige LAIR2 Antikörper) genetic variants are associated with regulation of gene expression and variable pemphigus foliaceus (zeige DSG1 Antikörper) susceptibility, and show indirect association of LAIR2 (zeige LAIR2 Antikörper) differential mRNA expression with pemphigus foliaceus (zeige DSG1 Antikörper) pathogenesis.
A LAIR1 insertion generates broadly reactive antibodies against malaria variant antigens;findings illustrate, with a biologically relevant example, a novel mechanism of antibody diversification by interchromosomal DNA transposition
C1q-mediated repression of human monocytes is regulated by LAIR-1
These data suggest that LAIR-1 has a relevant impact on EOC progression and may be helpful for a better understanding of molecular pathogenesis of cancer.
LAIR1 expression is a reliable and inexpensive marker capable of independently predicting time to first treatment in newly diagnosed unselected patients with chronic lymphocytic leukemia.
The expression of LAIR -1 on pDCs of juvenile systemic lupus erythematosus patients was significantly lower than that of control patients.
a novel pathway for the immunomodulatory functions of SP-D (zeige SFTPD Antikörper) mediated via binding of its collagenous domains to LAIR-1.
LAIR-1 may play an important role in immune imbalance in children with immune thrombocytopenia.
The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including NK cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily.
leukocyte-associated immunoglobulin-like receptor 1
, leukocyte-associated Ig-like receptor 1
, leukocyte-associated Ig-like receptor-1