anti-Lamin B Receptor (LBR) Antikörper

The protein encoded by LBR belongs to the ERG4/ERG24 family. Zusätzlich bieten wir Ihnen Lamin B Receptor Proteine (4) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
LBR 3930 Q14739
LBR 98386 Q3U9G9
LBR 89789 O08984
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Top anti-Lamin B Receptor Antikörper auf antikoerper-online.de

Showing 10 out of 85 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-LBR Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: RPMI 8226 cell lysate LBR is supported by BioGPS gene expression data to be expressed in RPMI 8226 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$319.00
Details
Human Ziege Unkonjugiert IHC, IHC (p) Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$484.00
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, IHC (p), WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$727.83
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p) Immunohistochemistry-Paraffin: Lamin B Receptor Antibody [NBP2-14185] - Staining of human lymph node shows distinct nuclear membranous positivity in lymphoid cells. Immunocytochemistry/Immunofluorescence: Lamin B Receptor Antibody [NBP2-14185] Staining of human cell line U-2 OS shows positivity in nuclear membrane and mitochondria. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$494.38
Details
Human Kaninchen Unkonjugiert ICC, IF, WB Immunocytochemistry/Immunofluorescence: Lamin B Receptor Antibody  - Staining of human cell line RH-30 shows localization to nuclear membrane. Western Blot: Lamin B Receptor Antibody  - Western blot analysis in human cell line RT-4, human cell line U-251 MG, human plasma, human liver tissue and human tonsil tissue. 100 μL Anmelden zum Anzeigen 10 bis 13 Tage
$494.38
Details
Human Kaninchen Unkonjugiert ELISA, IHC, WB Western blot analysis of Hela whole cell lysates, using LBR Antibody. The lane on the left is treated with the antigen-specific peptide. ABIN6277599 at 1/100 staining Mouse heart tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL Anmelden zum Anzeigen 11 bis 12 Tage
$390.77
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse embryo labeled with Rabbit Anti Lamin B Receptor Polyclonal Antibody, Unconjugated (ABIN709391) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded humanlung carcinoma labeled with Rabbit Anti Lamin B Receptor Polyclonal Antibody, Unconjugated (ABIN709391) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$317.90
Details
Human Kaninchen Unkonjugiert ELISA, IHC (p), WB   100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$280.00
Details
Human Maus Unkonjugiert IF, IHC (p), WB Western Blot analysis of LBR expression in transfected 293T cell line by LBR MaxPab polyclonal antibody.Lane 1: LBR transfected lysate(67.65 KDa).Lane 2: Non-transfected lysate. Immunofluorescence of purified MaxPab antibody to LBR on HeLa cell. [antibody concentration 10 ug/ml] 50 μg Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
Details
Human Kaninchen Unkonjugiert IHC, WB Immunohistochemistry of paraffin-embedded rat brain using LBR antibody at dilution of 1:200 (40x lens). 100 μL Anmelden zum Anzeigen 16 Days
$366.77
Details

Weitere Antikörper gegen Lamin B Receptor Interaktionspartner

Fruit Fly (Drosophila melanogaster) Lamin B Receptor (LBR) Interaktionspartner

  1. dLBR is not a limiting component of the nuclear architecture in Drosophila cells during the first 2 days of development

Zebrafish Lamin B Receptor (LBR) Interaktionspartner

  1. Data indicate that the LBR of zebrafish and mammals are both required for correct development of embryos.

Xenopus laevis Lamin B Receptor (LBR) Interaktionspartner

  1. LBR targets the membrane precursor vesicles to chromatin by interacting with importin beta in a LBR phosphorylation-dependent manner during the NE assembly at the end of mitosis

Human Lamin B Receptor (LBR) Interaktionspartner

  1. The authors demonstrate that human LBR is essential for cholesterol synthesis.

  2. These observations point to a new mechanism regulating the localization of LBR, which is governed by an ELYS-mediated phosphorylation network.

  3. The primary response of cells to various stresses leading to senescence consists of the down-regulation of LBR and LB1 to attain reversal of the chromatin architecture.

  4. We have shown here that lamin B receptor (LBR) showed a change in localization in both BrdU-induced and replicative senescent cells.

  5. Data indicate that proto-oncogene protein c-akt (Akt) phosphorylates distinct sites than SRPK1 protein within the arginine-serine (RS) domain of Lamin B Receptor (LBR).

  6. Lamin B receptor mRNA expression was directly associated with tumor grade in breast cancer patients(grade 1 vs. grade 3 - 0.00 vs. 0.00; p = 0.0479) and Nottingham Prognostic Index (NPI1 vs. NPI3 - 0.00 vs. 0.00; p = 0.0551).

  7. Mutation in LBR gene is associated with pelger-huet anomaly and a mild skeletal phenotype.

  8. Lymphohematopoietic licence: sterol C-14 reductase activity of lamin B receptor (Lbr) is essential for neutrophil differentiation.

  9. LBR missense mutations can abolish sterol reductase activity, causing lethal Greenberg dysplasia but not Pelger anomaly

  10. The LBR knockdown cells retain an ovoid shaped nucleus with reduced levels of lamin A/C during in vitro granulopoiesis induced with retinoic acid.

  11. Our studies reveal for the first time a mechanism that controls the timing of nuclear envelope reassembly through modification of the integral nuclear membrane protein lamin B receptor

  12. a highly significant gene-dosage effect between the gene copy number and the nuclear segmentation index of neutrophils

  13. LBR is heavily expressed in papillary thyroid carcinoma cells, but an abnormal folding of the protein might explain its lack of immunohistochemical reactivity and be associated with the anomalous folding of the nuclear membrane.

  14. LBR targets the membrane precursor vesicles to chromatin by interacting with importin beta in a LBR phosphorylation-dependent manner during the NE assembly at the end of mitosis

  15. LBR mutant variants and sterol reductases can severely interfere with the regular organization of the nuclear envelope and the endoplasmic reticulum.

  16. results suggest that LMNA, ZMPSTE24, and LBR sequence variations are not major genetic determinants involved in scleroderma pathogenesis

  17. The binding of lamin B receptor to chromatin is regulated by phosphorylation in the arginine-serine repeat-containing REGION

  18. Mutations in the gene encoding the lamin B receptor produce an altered nuclear morphology in granulocytes (Pelger-Huet anomaly).

  19. Autosomal recessive HEM/Greenberg skeletal dysplasia is caused by 3 beta-hydroxysterol delta 14-reductase deficiency due to mutations in this gene.

  20. examination of temporal association with protamine 1 during spermiogenesis

Mouse (Murine) Lamin B Receptor (LBR) Interaktionspartner

  1. Lbr deficiency could be related to Premature Ageing reflected by enhanced accumulation of protein glycation as a biomarker for ageing.

  2. The diffusional mobility of full-length LBR shows significant regional variation along the nuclear envelope, consistent with the existence of discrete LBR microdomains and the occurrence of multiple, asymmetrically-spaced anastomoses along the nuclear envelope-endoplasmic reticulum interface. Native LBR may be "configured" by long-range interactions between adjacent transmembrane domains and parts of the NH2 region.

  3. These results show a moderate skin differentiation phenotype, which indicates that upregulation of LBR is not the sole contributor to the Hutchinson-Gilford progeria syndrome phenotype.

  4. The N-terminal portion of LBR is probably responsible for the binding to HP1b.

  5. Study identified LBR- and lamin-A/C-dependent mechanisms tethering heterochromatin to the nuclear envelope. The two tethers are sequentially used during cellular differentiation and development: first the LBR- and then the lamin-A/C-dependent tether.

  6. LBR deficiency affects not only nuclear architecture but also proliferation, cell viability, and gene expression of hematopoietic cells

  7. sterol Delta(14) reductase domain of LBR plays a critical role in cholesterol biosynthesis and that this process is essential to both myeloid cell growth and functional maturation.

  8. Lbr, under transcriptional regulation of C/EBPepsilon, is necessary for morphological but not necessarily functional granulocyte maturation.

  9. lamin B receptor, although residing in nuclear membranes, may contribute to cholesterol biosynthesis in Tm7sf2((-/-)) mice

Lamin B Receptor (LBR) Antigen-Profil

Protein Überblick

The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.

Genbezeichner und Symbole assoziert mit anti-Lamin B Receptor (LBR) Antikörper

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  • lbr-A Antikörper
  • LMN2R Antikörper
  • Nbp60 Antikörper
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  • sb:cb406 Antikörper
  • TDRD18 Antikörper
  • wu:fb75h08 Antikörper
  • wu:fc47b04 Antikörper
  • wu:fd36b07 Antikörper
  • Xp58 Antikörper
  • zgc:86649 Antikörper

Bezeichner auf Proteinebene für anti-Lamin B Receptor (LBR) Antikörper

CG17952-PA , CG17952-PB , CG17952-PC , LBR-PA , LBR-PB , LBR-PC , lamin B receptor , lamin-B receptor , lamin-B receptor-like , integral nuclear envelope inner membrane protein , tudor domain containing 18 , ichthyosis , Lamin-B receptor

GENE ID SPEZIES
100056997 Equus caballus
37482 Drosophila melanogaster
368360 Danio rerio
378609 Xenopus laevis
457776 Pan troglodytes
490391 Canis lupus familiaris
700801 Macaca mulatta
100145693 Xenopus (Silurana) tropicalis
100415074 Callithrix jacchus
100470463 Ailuropoda melanoleuca
100594061 Nomascus leucogenys
3930 Homo sapiens
98386 Mus musculus
89789 Rattus norvegicus
509348 Bos taurus
396285 Gallus gallus
100174610 Pongo abelii
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