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KLF5 encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. Zusätzlich bieten wir Ihnen KLF5 Kits (9) und KLF5 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 77 products:
Human Polyclonal KLF5 Primary Antibody für IF (p), IHC (p) - ABIN739515
Zhang, Ha, Larouche, Swanson, Goldowitz: Kruppel-Like Factor 4 Regulates Granule Cell Pax6 Expression and Cell Proliferation in Early Cerebellar Development. in PLoS ONE 2015
Human Polyclonal KLF5 Primary Antibody für FACS, IF - ABIN391515
Guo, Dong, Zhang, Zhao, Sun, Li, Dong: Pro-proliferative factor KLF5 becomes anti-proliferative in epithelial homeostasis upon signaling-mediated modification. in The Journal of biological chemistry 2009
Show all 2 Pubmed References
Human Polyclonal KLF5 Primary Antibody für ICC, IF - ABIN4329154
Chen, Lin, Tang: Matrix-Stiffness-Regulated Inverse Expression of Krüppel-Like Factor 5 and Krüppel-Like Factor 4 in the Pathogenesis of Renal Fibrosis. in The American journal of pathology 2015
any one of Klf2 (zeige KLF2 Antikörper), Klf4 (zeige KLF4 Antikörper) and Klf5 was sufficient to support self-renewal of mouse embryonic stem cells, whereas the removal of all three compromised it.
the regulatory crosstalk between KLF5, miR (zeige MLXIP Antikörper)-29a, and Fbw7/CDC4 (zeige FBXW7 Antikörper) cooperatively promotes atherosclerotic development
KLF5 as an essential factor required for acinar-to-ductal metaplasia and oncogenic KRAS-induced pancreatic tumor formation.
lf5 ChIP-seq revealed that Klf5 binding overlaps that of MyoD (zeige MYOD1 Antikörper) and Mef2 (zeige MEF2C Antikörper), and Klf5 physically associates with both MyoD (zeige MYOD1 Antikörper) and Mef2 (zeige MEF2C Antikörper). In addition, MyoD (zeige MYOD1 Antikörper) recruitment was greatly reduced in the absence of Klf5. These results indicate that Klf5 is an essential regulator of skeletal muscle differentiation, acting in concert with myogenic transcription factors such as MyoD (zeige MYOD1 Antikörper) and Mef2 (zeige MEF2C Antikörper).
KLF5 regulates intestinal barrier function by mediating the transcription of DSG2 (zeige DSG2 Antikörper), a gene encoding a major component of desmosome structures
Klf5 suppresses Fgf4 (zeige FGF4 Antikörper)-Fgfr (zeige FGFR2 Antikörper)-ERK (zeige EPHB2 Antikörper) signalling, thus preventing precocious activation of the primitive endoderm specification programme
In conclusion, the results of this study suggest that the presence of KLF5 in postn (zeige POSTN Antikörper)-positive cells contributes to the pathogenesis of aortic thickening induced by DOCA-salt hypertension.
these studies demonstrate dual functions of Klf5 in regulating hematopoietic stem and progenitor proliferation and localization in the bone marrow, as well as lineage choice after GMP (zeige NT5C2 Antikörper), promoting increased neutrophil output at the expense of eosinophil production.
Collectively, we identify a novel regulatory pathway in which 1, 25(OH)2D3 induces VDR (zeige CYP27B1 Antikörper) expression and promotes VDR (zeige CYP27B1 Antikörper) interaction with p50 subunit of NF-kappaB (zeige NFKB1 Antikörper), which in turn attenuates the association of KLF5 with p50 subunit of NF-kappaB (zeige NFKB1 Antikörper) and thus exerts anti-inflammatory and anti-proliferative effects on macrophages.
KLF5-dependent regulation of Myo9b (zeige MYO9B Antikörper)/RhoA (zeige RHOA Antikörper) is required for podosome formation and macrophage migration during abdominal aortic aneurysm.
correlation between the KLF5 and ZEB1 (zeige ZEB1 Antikörper) transcription levels in the pancreatic tumor tissues
The present study has identified that KLF5, a target of miR (zeige MLXIP Antikörper)-145-5p, is a key marker gene in cancer. miR (zeige MLXIP Antikörper)-145-5p may also contribute to the dysregulation of other functional genes during tumor development.
the knockdown of HDAC1 (zeige HDAC1 Antikörper)/2 upregulated KLF5 protein but not KLF5 mRNA, and the increase in KLF5 protein level by silencing HDAC1 (zeige HDAC1 Antikörper)/2 was at least in part due to decreased proteasomal degradation.
KLF5 expression in tumor stroma was closely associated with clinicopathological features such as tumor size, invasion depth, cell grade and lymph node metastasis, as well as poor prognosis in patients with gastric cancer.
KLF5 has a role in regulating IL1beta (zeige IL1B Antikörper) induced intervertebral disc metabolism
Levels of KLF5 are increased in human pancreatic ductal adenocarcinoma.
Data demonstrate that KLF5 inhibits ccRCC growth as a tumor suppressor and highlight the potential of 5-Aza-CdR (zeige RUNX1T1 Antikörper) to release KLF5 expression as a therapeutic modality for the treatment of ccRCC.
The present study found that the KLF4 (zeige KLF4 Antikörper) and KLF5 3'-UTR (zeige UTS2R Antikörper) contains one conserved target site of miR (zeige MLXIP Antikörper)-506 and miR (zeige MLXIP Antikörper)-124, and the overexpression of miR (zeige MLXIP Antikörper)-506 and miR (zeige MLXIP Antikörper)-124 inhibited the H2O2-induced upregulation of KLF4 (zeige KLF4 Antikörper) and KLF5 in HCMs.
miR (zeige MLXIP Antikörper)-5195-3p suppressed proliferation and invasion of human bladder cancer cells via suppression of KLF5.
miR (zeige MLXIP Antikörper)-217 suppresses triple-negative breast cancer cell growth, migration, and invasion. MiR (zeige MLXIP Antikörper)-217 suppresses triple-negative breast cancer, at least partially, through down-regulating the KLF5 expression.
This gene encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. Since the protein localizes to the nucleus and binds the epidermal growth factor response element, it is thought to be a transcription factor.
Kruppel-like factor 5 (intestinal)
, Krueppel-like factor 5-like
, Kruppel-like factor 5
, basic-transcription-element-binding-protein 2
, basic transcription element binding protein 2
, basic transcription element binding protein BTEB2
, BTE-binding protein 2
, Krueppel-like factor 5
, basic transcription element-binding protein 2
, intestinal-enriched krueppel-like factor
, transcription factor BTEB2
, GC box binding protein 2
, GC-box-binding protein 2
, colon krueppel-like factor
, colon kruppel-like factor
, intestinal-enriched kruppel-like factor