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The protein encoded by KRT19 is a member of the keratin family. Zusätzlich bieten wir Ihnen Keratin 19 Antikörper (1071) und Keratin 19 Kits (47) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 34 products:
CYFRA 21-1 assessed at the end of RT or ChT (zeige ChT Proteine) seems to be a prognostic marker for tumor response. A high concentration of CYFRA 21-1 after treatment increases the risk of death. CYFRA 21-1 might be suggested in the monitoring of carcinomas of head and neck cancer (HNC (zeige MMP8 Proteine)).
the modulation of KRT19 expression could be involved in cancer stem cell reprogramming and drug sensitivity.
Data indicate that de novo expression of KRT7 (zeige KRT7 Proteine) and KRT19 resulting in altered plasticity and stem cell characteristics of epithelial cells might be a crucial factor in increasing the risk of tumor development in end-stage kidneys.
High expression of CK-19 is associated with intrahepatic cholangiocarcinoma.
KRT19 intracellularly binds to HER2 (zeige ERBB2 Proteine), playing a critical role in HER2 (zeige ERBB2 Proteine) activation
The combined use of CK19 and CD56 (zeige NCAM1 Proteine) is helpful in discriminating papillary thyroid carcinoma and its variants from other mimicking thyroid lesions.
YAP1 (zeige YAP1 Proteine) activation was more commonly found in CCAs than in pure HCCs (zeige HCCS Proteine). However, a differing pattern of YAP1 (zeige YAP1 Proteine) expression between cHC-CCAs and CK19(+) HCCs (zeige HCCS Proteine) and the poor prognosis of YAP1 (zeige YAP1 Proteine) positive hepatic carcinomas suggests that YAP1 (zeige YAP1 Proteine) may have a preferential role in aggressive tumor behavior, rather than in the determination of cellular lineage in hepatic carcinomas
Circulating tumor cells expressing cytokeratin and tumor-initiating cell markers, including ALDH, CD133, and CD44, were identified in patients with pancreatic adenocarcinoma. These TIC-like CTCs were associated with poor prognosis after surgical resection and with an increased incidence of tumor recurrence
Aberrant decreased miR (zeige MLXIP Proteine)-26a could promote cell proliferation by regulating KRT19 which plays important role in the pathogenesis of cholangiocarcinoma.
The detection of TK1 (zeige TK1 Proteine) combined with that of cytokeratin-19 fragment (CYFRA21-1), CEA (zeige CEACAM5 Proteine) or NSE (zeige ENO2 Proteine) increased the diagnostic value of TK1 (zeige TK1 Proteine) for lung squamous cell carcinoma, adenocarcinoma and small cell lung cancer, respectively.
Cytokeratin-19 (CK-19)+ specific deletion of tumor suppressors p53 (zeige TP53 Proteine) and Retinoblastoma (Rb) indicated that carcinomas at the injury site originates from cholangiocytes or liver progenitor cells.
Demonstrate that K19 plays an important role in the ductular reaction that constitutes the basic regenerative response to chronic liver injury.
Branched desmin (zeige DES Proteine)-deficient (DKO) myofibers show significantly faster rates of calcium ion (Ca2 (zeige CA2 Proteine)+) clearance, with milder branching phenotype observed in DKO muscle suggesting that absence of keratin-19 corrects the defect created by absence of desmin (zeige DES Proteine) alone.
the structural response of each genotype is distinct, suggesting multiple mechanisms by which desmin and keratin influence the biomechanical properties of myofibers
The expression of CK19 and EGFR (zeige EGFR Proteine) in lymphatic metastasis of laryngeal carcinoma was higher than in controls.
Results suggest that keratin filaments containing K19- and desmin (zeige DES Proteine)-based intermediate filaments can play independent, complementary, or antagonistic roles in the physiology and morphology of fast-twitch skeletal muscle.
a dual mechanism of how PDX-1 (zeige PDX1 Proteine) negatively regulates Krt19 ductal specific gene expression
expression of nestin (zeige NES Proteine) and cytokeratin 19 is a normal property of embryonic stem cells preceding differentiation into C-peptide/insulin (zeige INS Proteine)-producing cells without any selection for nestin (zeige NES Proteine)-positive phenotypes
loss of the keratin cytoskeleton causes defects in the trophoblast giant cell layer
transduction of PDX1 (zeige PDX1 Proteine) in primary pancreatic ductal cells suppresses K19 expression, and short interfering RNA to PDX1 (zeige PDX1 Proteine) in Min6 insulinoma (zeige RPS15 Proteine) cells and results in the induction of normally undetectable K19
The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21.
40-kDa keratin intermediate filament
, cytokeratin 19
, keratin, type I cytoskeletal 19
, keratin, type I, 40-kd
, keratin complex 1, acidic, gene 19
, type I keratin KA19
, keratin 19
, Keratin, type I cytoskeletal 19
, keratin, type I cytoskeletal 19-like
, keratin 19, type I