Keratin 19 Proteine (KRT19)

The protein encoded by KRT19 is a member of the keratin family. Zusätzlich bieten wir Ihnen Keratin 19 Antikörper (1063) und Keratin 19 Kits (47) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
KRT19 3880 P08727
KRT19 16669 P19001
KRT19 360626 Q63279
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Top Keratin 19 Proteine auf

Showing 10 out of 34 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
Escherichia coli (E. coli) Human His tag Validation with Western Blot 50 μg Anmelden zum Anzeigen 11 Days
Insect cells (Sf9) Human DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 11 Days
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 11 Days
Escherichia coli (E. coli) Maus His tag   100 μg Anmelden zum Anzeigen 15 bis 18 Tage
Escherichia coli (E. coli) Human Unkonjugiert   100 μg Anmelden zum Anzeigen 11 bis 16 Tage
Escherichia coli (E. coli) Human Unkonjugiert SDS-PAGE analysis of Human Keratin 19 Protein. 100 μg Anmelden zum Anzeigen 11 bis 18 Tage
Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 15 bis 19 Tage
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage

KRT19 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , ,
, , ,
Mouse (Murine)

Rat (Rattus)

Weitere Proteine zu Keratin 19 (KRT19) Interaktionspartnern

Human Keratin 19 (KRT19) Interaktionspartner

  1. The findings reveal KRT19 expression in hepatocellular carcinoma is regulated by cross-talk between cancer-associated fibroblasts and hepatocellular carcinoma cells, illuminating new therapeutic targets for this aggressive disease.

  2. Low CK19 expression is associated with Thyroid Papillary Carcinoma.

  3. Cyfra 21.1 is a tool available to independently predict survival of DTC patients not achieving excellent response after primary treatment.

  4. elevated level of preoperative serum Cyfra 21-1 indicates an advanced stage of tumor

  5. CYFRA 21-1 assessed at the end of RT or ChT seems to be a prognostic marker for tumor response. A high concentration of CYFRA 21-1 after treatment increases the risk of death. CYFRA 21-1 might be suggested in the monitoring of carcinomas of head and neck cancer (HNC).

  6. the modulation of KRT19 expression could be involved in cancer stem cell reprogramming and drug sensitivity.

  7. Data indicate that de novo expression of KRT7 and KRT19 resulting in altered plasticity and stem cell characteristics of epithelial cells might be a crucial factor in increasing the risk of tumor development in end-stage kidneys.

  8. High expression of CK-19 is associated with intrahepatic cholangiocarcinoma.

  9. KRT19 intracellularly binds to HER2, playing a critical role in HER2 activation

  10. The combined use of CK19 and CD56 is helpful in discriminating papillary thyroid carcinoma and its variants from other mimicking thyroid lesions.

  11. CYFRA 21-1 can be useful as a tumor marker for evaluating tumor progression and treatment efficacy in patients with extramammary Paget's disease.

  12. YAP1 activation was more commonly found in CCAs than in pure HCCs. However, a differing pattern of YAP1 expression between cHC-CCAs and CK19(+) HCCs and the poor prognosis of YAP1 positive hepatic carcinomas suggests that YAP1 may have a preferential role in aggressive tumor behavior, rather than in the determination of cellular lineage in hepatic carcinomas

  13. Circulating tumor cells expressing cytokeratin and tumor-initiating cell markers, including ALDH, CD133, and CD44, were identified in patients with pancreatic adenocarcinoma. These TIC-like CTCs were associated with poor prognosis after surgical resection and with an increased incidence of tumor recurrence

  14. Aberrant decreased miR-26a could promote cell proliferation by regulating KRT19 which plays important role in the pathogenesis of cholangiocarcinoma.

  15. The detection of TK1 combined with that of cytokeratin-19 fragment (CYFRA21-1), CEA or NSE increased the diagnostic value of TK1 for lung squamous cell carcinoma, adenocarcinoma and small cell lung cancer, respectively.

  16. Our results are of special importance against the background that CK19 positive carcinomas revealed a significantly poorer prognosis and therefore emphasize its prognostic and possible diagnostic role in tongue cancer.

  17. (18)F-FDG-PET can be used to predict K19 expression in hepatocellular carcinoma and should thereby aid in the development of novel therapeutic strategies targeting K19(+) hepatocellular carcinoma cancer stem cells

  18. Immunohistochemical assessment of both CK19 and SCCAg status in histologically negative sentinel lymph nodes may be a valuable approach for predicting recurrence and survival after curative surgery for cervical squamous cell carcinoma.

  19. Positive CK-19 expression can be used as a predictor of poor prognosis of PNET

  20. Data suggest that high cytokeratin 19 (CK19) levels in peripheral blood may independently predict non-sentinel lymph node (nSLN) metastasis in breast cancer patients.

Mouse (Murine) Keratin 19 (KRT19) Interaktionspartner

  1. Cytokeratin-19 (CK-19)+ specific deletion of tumor suppressors p53 and Retinoblastoma (Rb) indicated that carcinomas at the injury site originates from cholangiocytes or liver progenitor cells.

  2. Demonstrate that K19 plays an important role in the ductular reaction that constitutes the basic regenerative response to chronic liver injury.

  3. Branched desmin-deficient (DKO) myofibers show significantly faster rates of calcium ion (Ca2+) clearance, with milder branching phenotype observed in DKO muscle suggesting that absence of keratin-19 corrects the defect created by absence of desmin alone.

  4. the structural response of each genotype is distinct, suggesting multiple mechanisms by which desmin and keratin influence the biomechanical properties of myofibers

  5. The expression of CK19 and EGFR in lymphatic metastasis of laryngeal carcinoma was higher than in controls.

  6. Results suggest that keratin filaments containing K19- and desmin-based intermediate filaments can play independent, complementary, or antagonistic roles in the physiology and morphology of fast-twitch skeletal muscle.

  7. a dual mechanism of how PDX-1 negatively regulates Krt19 ductal specific gene expression

  8. expression of nestin and cytokeratin 19 is a normal property of embryonic stem cells preceding differentiation into C-peptide/insulin-producing cells without any selection for nestin-positive phenotypes

  9. loss of the keratin cytoskeleton causes defects in the trophoblast giant cell layer

  10. transduction of PDX1 in primary pancreatic ductal cells suppresses K19 expression, and short interfering RNA to PDX1 in Min6 insulinoma cells and results in the induction of normally undetectable K19

  11. This is the first demonstration of a mammalian phenotype associated with a genetic perturbation of keratin 19.

  12. Keratin absence or mutation is well tolerated after pancreatic but not liver injury, whereas excessive overexpression is toxic to the pancreas but not the liver when induced under basal conditions.

  13. A CK19(CreERT) knockin mouse line allows for conditional DNA recombination in epithelial cells in multiple endodermal organs.

  14. gene expression of krt8, krt18, and krt19 and correlation with gene expression profiles and cell differentiation are compared in human and mouse embryonic stem cells

  15. Plastin 1 accumulates in the terminal web and interacts with keratin 19, possibly contributing to anchoring the rootlets to the keratin network.

Keratin 19 (KRT19) Protein Überblick

Protein Überblick

The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21.

Genbezeichner und Symbole assoziert mit Keratin 19 Proteine (KRT19)

  • keratin 19 (KRT19)
  • keratin 19 (Krt19)
  • keratin 19 (krt19)
  • keratin 19 L homeolog (krt19.L)
  • keratin, type I cytoskeletal 19 (LOC100344434)
  • keratin, type I cytoskeletal 19 (LOC101117946)
  • AI663979 Protein
  • ck19 Protein
  • EndoC Protein
  • GK-19 Protein
  • k1cs Protein
  • k19 Protein
  • Ka19 Protein
  • Krt-1.19 Protein
  • Krt1-19 Protein
  • krt9 Protein
  • krt15 Protein
  • KRT19 Protein
  • MGC76282 Protein
  • MGC83069 Protein

Bezeichner auf Proteinebene für Keratin 19 Proteine (KRT19)

40-kDa keratin intermediate filament , CK-19 , cytokeratin 19 , cytokeratin-19 , keratin, type I cytoskeletal 19 , keratin, type I, 40-kd , keratin-19 , keratin complex 1, acidic, gene 19 , K19 , type I keratin KA19 , keratin 19 , Keratin, type I cytoskeletal 19 , keratin, type I cytoskeletal 19-like , keratin 19, type I

3880 Homo sapiens
16669 Mus musculus
360626 Rattus norvegicus
394514 Xenopus (Silurana) tropicalis
395861 Gallus gallus
432054 Xenopus laevis
454663 Pan troglodytes
514812 Bos taurus
779233 Xenopus laevis
100173010 Pongo abelii
100398836 Callithrix jacchus
100587819 Nomascus leucogenys
100685481 Canis lupus familiaris
100713456 Cavia porcellus
100515339 Sus scrofa
100344434 Oryctolagus cuniculus
100147127 Equus caballus
101117946 Ovis aries
106501743 Capra hircus
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