anti-Keratin 14 (KRT14) Antikörper

KRT14 encodes a member of the keratin family, the most diverse group of intermediate filaments. Zusätzlich bieten wir Ihnen Keratin 14 Proteine (17) und Keratin 14 Kits (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
KRT14 3861 P02533
KRT14 16664 Q61781
KRT14 287701 Q6IFV1
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Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Rind (Kuh) Meerschweinchen Unkonjugiert IHC (fro), IHC (p), WB   0.1 mL 6 bis 8 Tage
Human Kaninchen Unkonjugiert IHC (p), WB Cytokeratin 14 was detected in paraffin-embedded sections of human oesophagus squama cancer tissues using rabbit anti- Cytokeratin 14 Antigen Affinity purified polyclonal antibody (Catalog # ) at 1 µg/mL. The immunohistochemical section was developed using SABC method (Catalog # SA1022). Cytokeratin 14 was detected in paraffin-embedded sections of human oesophagus squama cancer tissues using rabbit anti- Cytokeratin 14 Antigen Affinity purified polyclonal antibody (Catalog # ) at 1 µg/mL. The immunohistochemical section was developed using SABC method (Catalog # SA1022). 100 μg 4 bis 6 Tage
Meerschweinchen Kaninchen Unkonjugiert WB WB Suggested Anti-KRT14 Antibody Titration:  1.25ug/ml  ELISA Titer:  1:312500  Positive Control:  Human Thymus Host:  Mouse  Target Name:  KRT14  Sample Tissue:  Mouse Testis  Antibody Dilution:  1ug/ml 100 μL 2 bis 3 Tage
Human Kaninchen Unkonjugiert ELISA, IHC (p), WB Immunohistochemistry (IHC) analysis of paraffin-embedded Rat Brain, antibody was diluted at 1:100. 100 μL Verfügbar
Human Kaninchen Unkonjugiert WB Western blot analysis of Cytokeratin 14 expression in A549 (A), Raw264.7 (B), H9C2 (C) whole cell lysates. 200 μL 13 bis 14 Tage
Human Kaninchen Unkonjugiert IC, IF, IHC, WB Immunofluorescent analysis of Cytokeratin 14 staining in MCF7 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of Cytokeratin 14 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL 13 bis 14 Tage
Human Maus Unkonjugiert FACS, IHC (fro), IF, IHC (p), WB   20 μg 6 bis 8 Tage
Human Kaninchen Unkonjugiert ICC, IHC (fro), IF, IHC (p), IHC, WB WB Image Sample(30 μg of whole cell lysate) A:HeLa S3, 7.5% SDS PAGE antibody diluted at 1:3000 ICC/IF Image Cytokeratin 14 antibody detects Cytokeratin 14 protein at cytoplasm by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: Cytokeratin 14 protein stained by Cytokeratin 14 antibody , diluted at 1:200. Red: alpha Tubulin, a cytoskeleton marker, stained by alpha Tubulin antibody [GT114] , diluted at 1:1000. Blue: Hoechst 33342 staining. 100 μL 3 bis 4 Tage
Human Maus FITC FACS, IF   0.1 mg 6 bis 8 Tage
Human Kaninchen Unkonjugiert IF, IHC, ELISA, WB Western blot analysis of extracts from NIH-3T3 cells, using Keratin 14 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using Keratin 14 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg 2 bis 3 Tage

Am meisten referenzierte anti-Keratin 14 Antikörper

  1. Human Monoclonal KRT14 Primary Antibody für ICC, FACS - ABIN335329 : Bauwens, De Groot, Ramaekers, Veldman, Huizing: Expression of intermediate filament proteins in the adult human vestibular labyrinth. in The Annals of otology, rhinology, and laryngology 1992 (PubMed)
    Show all 9 Pubmed References

  2. Cow (Bovine) Polyclonal KRT14 Primary Antibody für IHC (fro), IHC (p) - ABIN113455 : Herrmann, van der Hoeven, Grone, Stewart, Langbein, Kaiser, Liebisch, Gosch, Buchkremer, Drobnik, Schmitz, Stremmel: Mice with targeted disruption of the fatty acid transport protein 4 (Fatp 4, Slc27a4) gene show features of lethal restrictive dermopathy. in The Journal of cell biology 2003 (PubMed)
    Show all 8 Pubmed References

  3. Human Monoclonal KRT14 Primary Antibody für ICC, FACS - ABIN335217 : Bonfrer, Groeneveld, Korse, van Dalen, Oomen, Ivanyi: Monoclonal antibody M3 used in tissue polypeptide-specific antigen assay for the quantification of tissue polypeptide antigen recognizes keratin 18. in Tumour biology 1994 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen Keratin 14 Interaktionspartner

Human Keratin 14 (KRT14) Interaktionspartner

  1. we summarized the various aspects of the presence of KRT5 and KRT14 in the epidermis, their relation to the incidence and severity of epidermolysis bullosa simplex phenotypes, and the processes with which these proteins can affect them.

  2. Recessive KRT14 epidermolysis bullosa simplex (EBS) should be clinically differentiated from other EB forms, and also from epidermolytic ichthyosis due to the presence of hyperkeratotic lesions in addition to blisters

  3. Data indicate keratins K5/K14 and p53 homolog p63 as markers of breast epithelial stem cells.

  4. High CK14 expression is associated with lymph node metastasis in oral squamous cell carcinoma.

  5. Efficient homology-directed repair of a dominant negative KRT14 mutation via CRISPR/Cas9 nickases in epidermolysis bullosa simplex patients' keratinocytes has been reported.

  6. Immunocytochemical staining using cocktail antibody targeting p63/CK14 was useful for the differential diagnosis of FA and DCIS in FNAC of the breast.

  7. the findings show that squamous and micropapillary bladder cancers have different expression patterns of CK14 and FOXA1 and suggest that they arise from distinct precursors.

  8. PADI4 contributes to gastric tumorigenesis by upregulating CXCR2, KRT14 and TNF-alpha expression.

  9. this study adds a further 10 novel mutations to the catalogued genotype-phenotype correlations in epidermolysis bullosa simplex and demonstrates a potential modifying effect of SNPs on the phenotype. We therefore support the notion of full DNA sequencing of both KRT5 and KRT14 genes so as to not miss any variants in the genes contributing to the phenotype.

  10. The novel c.1234A>G(p.Ile412Val) mutation of the KRT14 gene is probably responsible for the disease.

  11. Keratin14/p63-positive epithelial proliferations suggest benign breast disease.

  12. K14 was coexpressed with alphav-integrin in fetal and adult corneas and cultured corneolimbal epithelium, and colony-forming efficiency (an indicator of stem cell activity) was similar in cells from both sources.

  13. Loss of keratin 14 is associated with epidermolysis bullosa.

  14. contributes to collective invasion of salivary adenoid cystic carcinoma and may be a biomarker of worse prognosis

  15. vimentin regulates the differentiation switch via modulation of K5/K14 expression. Moreover, because there was a significant correlation between high vimentin-K14 expression and recurrence/poor survival in oral cancer patients, vimentin-K14 together may prove to be the novel markers for the prognostication of human oral cancer.

  16. We concluded that smoking habits were capable of inducing changes in global DNA methylation, miR-9-3 methylation status and K19 expression.

  17. data demonstrates that keratinocyte migration requires the interaction between vimentin and keratins at the -YRKLLEGEE- sequence at the helical 2B domain of viment

  18. Immunocytochemistry using this antibody cocktail comprises five antibodies recognising p63, and cytokeratins ( 7, 18, 5 and 14) showed good sensitivity and specificity for diagnosing breast cancers. Thus, this method is useful for mammary cytology using FNA

  19. identification of 29 different mutations in KRT5 and KRT14, 11 of which were novel, in a Polish cohort of epidermolysis bullosa simplex patients

  20. findings reveal K14 as a key regulator of metastasis and establish the concept that K14(+) epithelial tumor cell clusters disseminate collectively to colonize distant organs

Mouse (Murine) Keratin 14 (KRT14) Interaktionspartner

  1. keratin 1 (K1) is essential for the persistent infection caused by LCMV strain MX, and its absence very effectively slows down the course of infection

  2. Cumulatively, these data indicate that altered CK14 (high) and CK18 (low) expression is perhaps an early event in bladder cancer tumorigenesis in females at least and is characteristic of both urothelial superficial pre-neoplastic and neoplastic lesions.

  3. KRT14 is expressed in a subpopulation of bladder basal cells with pivotal role in regeneration and tumorigenesis.

  4. CDK1, Aurora-B, and Rho-kinase phosphorylate keratin 5/14.

  5. RA regulates Krt5 and Krt14 expression independently of stem cell character in developing salivary epithelium. The stem cell gene Kit is regulated inversely from Krt5/Krt14 by RA signaling.

  6. Analysis of K14 variants with single or multiple substitutions of cysteine residues points to a spatial and temporal hierarchy in how Cys-4/Cys-40 and Cys-367 regulate keratin assembly in vitro and filament dynamics in live keratinocytes

  7. Disulfide bonding is a novel and important mechanism regulating the assembly, intracellular organization, and dynamics of K14-containing intermediate filaments in skin keratinocytes.

  8. K14-VEGF transgenic mouse a valuable model to study novel immunotherapies for psoriasis

  9. autoantibodies in Scurfy mice and patients with IPEX target keratin 14

  10. nipple connective tissue and its development: insights from the keratin 14-PTHrP mouse

  11. The keratin-14 IL-4 transgenic (Tg) mouse model of atopic dermatitis (AD) is characterized by skin infiltration of T cells, early up-regulation of T(h)2 cytokines and late surge of T(h)1 cytokines.

  12. These studies provide a potential mechanism by which deltaNp63 directly governs the expression of K14 in a keratinocyte-specific manner.

  13. Study describes the expression profile of claudins and keratin markers in the accelerated epidermal permeability barrier formation of K14-CaSR transgenic mice during development as compared to the wild type from E12.5 to newborn stages.

  14. IL-6 and IFN-gamma stimulated VEGF-A mRNA production in the skin and in primary keratinocytes of keratin 14 IL-4 transgenic mice

  15. DeltaNp63 alone can restore the expression of the basal keratins and reinitiate the failed epidermal differentiation program in the skin of p63 null animals.

Xenopus laevis Keratin 14 (KRT14) Interaktionspartner

  1. findings indicate that ouro1 and ouro2 participate in the process of tail regression as immune antigens and highlight the possibility that the acquired immune system contributes not only to self-defense but also to remodeling processes in morphogenesis.

Keratin 14 (KRT14) Antigen-Profil

Protein Überblick

This gene encodes a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12-p11.

Genbezeichner und Symbole assoziert mit anti-Keratin 14 (KRT14) Antikörper

  • keratin 14 (KRT14) Antikörper
  • keratin 14 (Krt14) Antikörper
  • keratin 14, type I L homeolog (krt14.L) Antikörper
  • AI626930 Antikörper
  • CK14 Antikörper
  • EBS3 Antikörper
  • EBS4 Antikörper
  • K14 Antikörper
  • Ka14 Antikörper
  • Krt-1.14 Antikörper
  • Krt1-14 Antikörper
  • NFJ Antikörper
  • ouro2 Antikörper

Bezeichner auf Proteinebene für anti-Keratin 14 (KRT14) Antikörper

CK-14 , cytokeratin 14 , cytokeratin-14 , keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner) , keratin, type I cytoskeletal 14 , keratin-14 , epidermolysis bullosa simplex, Dowling-Meara, Koebner , keratin complex 1, acidic, gene 14 , K14 , type I keratin Ka14 , cytokeratin VII , cytokeratin-7 , epidermal keratin VII , type I alpha-keratin 14 , keratin 14 , ouroboros 2 , keratin, type I cytoskeletal 14-like

3861 Homo sapiens
16664 Mus musculus
287701 Rattus norvegicus
404111 Bos taurus
408039 Gallus gallus
100310818 Xenopus laevis
100400152 Callithrix jacchus
100713272 Cavia porcellus
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