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The protein encoded by IL27 is one of the subunits of a heterodimeric cytokine complex. Zusätzlich bieten wir Ihnen IL27 Kits (54) und IL27 Proteine (26) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 164 products:
Mouse (Murine) Monoclonal IL27 Primary Antibody für ICS, Neut - ABIN2689756
Hall, Silver, Hunter: The immunobiology of IL-27. in Advances in immunology 2012
Show all 7 Pubmed References
Mouse (Murine) Monoclonal IL27 Primary Antibody für FACS - ABIN4896017
Yoshida, Yoshimi, Yoshii, Kim, Dey, Xiong, Munasinghe, Yazawa, ODonovan, Maximova, Sharma, Zhu, Wang, Morse, Ozato: The transcription factor IRF8 activates integrin-mediated TGF-β signaling and promotes neuroinflammation. in Immunity 2014
Mouse (Murine) Polyclonal IL27 Primary Antibody für WB - ABIN1043831
Pflanz, Timans, Cheung, Rosales, Kanzler, Gilbert, Hibbert, Churakova, Travis, Vaisberg, Blumenschein, Mattson, Wagner, To, Zurawski, McClanahan, Gorman, Bazan, de Waal Malefyt, Rennick, Kastelein: IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells. in Immunity 2002
Mouse (Murine) Monoclonal IL27 Primary Antibody für WB - ABIN1043835
Murugaiyan, Mittal, Weiner: Identification of an IL-27/osteopontin axis in dendritic cells and its modulation by IFN-gamma limits IL-17-mediated autoimmune inflammation. in Proceedings of the National Academy of Sciences of the United States of America 2010
Human Monoclonal IL27 Primary Antibody für CyTOF, FACS - ABIN4900122
Seyerl, Kirchberger, Majdic, Seipelt, Jindra, Schrauf, Stöckl: Human rhinoviruses induce IL-35-producing Treg via induction of B7-H1 (CD274) and sialoadhesin (CD169) on DC. in European journal of immunology 2010
our results showed that SNP rs153109 displayed significant associations with dilated cardiomyopathy in Chinese Han population, whereas no differences in genotype or allele frequencies were found between dilated cardiomyopathy patients and controls at SNP rs17855750.
Human Immunodeficiency virus type-1 myeloid derived suppressor cells inhibit cytomegalovirus inflammation through IL-27 and B7-H4 (zeige VTCN1 Antikörper).
IL-27 enhances the potential of reactive oxygen species generation from monocyte-derived macrophages and dendritic cells by induction of p47(phox).
IL-27 has a unique ability to directly act on hematopoietic stem cells and promote their expansion and differentiation into myeloid progenitors in hematologic neoplasms and malaria. (Review)
IL-27 rs153109 and rs17855750 Polymorphisms are associated with Risk and Response to Therapy in Acute Lymphoblastic Leukemia.
IL-27 was down-regulated in the malignant Middle Cerebral Artery Infarction.
IL-27 may be involved in the development of coronary artery lesions in acute Kawasaki disease.
Hepatitis B virus infection can lead to overexpression of interleukin-27 gene in liver transplant patients.
this study indicates that IL-27 secreted by cervical carcinoma cells restricts the angiogenesis in a paracrine manner in the pathogenesis of cervical cancer
IL-27 signaling (IL-27 and its receptor) may be involved in the pathogenesis of HIV infection and immune reconstitution in HIV/AIDS patients who underwent HAART. IL-27 may exert effects through regulating Th1 (zeige TH1L Antikörper) / Th2 ratio.
Mechanistic studies have identified that hyperlipidemia induces IL-27 production in a TLR4 (zeige TLR4 Antikörper)-dependent manner, likely via downregulating LXR (zeige NR1H3 Antikörper) expression in dendritic cells. In this case, mice lacking IL-27 do not develop enhanced antibody responses.
IFN-gamma (zeige IFNG Antikörper) induces IL-30 production which suppresses IFN-gamma (zeige IFNG Antikörper) mediated liver inflammation.
IL-27 signaling in Foxp3 (zeige FOXP3 Antikörper)(+) Tregs essential for Tregs to control autoimmune inflammation in the central nervous system
this study has revealed an important role of thymic dendritic cells-derived IL-27 in the regulation of the phenotypic maturation of CD4 (zeige CD4 Antikörper)(+) single positive thymocytes.
TTP (zeige ZFP36 Antikörper), encoded by Zfp36 (zeige ZFP36 Antikörper), degrades p28 (zeige GSTO1 Antikörper) to inhibit IL-27 production by macrophages and is thereby a negative regulator of the antitumour response.
these data infer that endopeptidase mediated gliadin degradation by macrophages and concomitant IL-27 production drive differentiation of splenic gliadin-specific Tr1 (zeige TXNRD1 Antikörper)-like cells in celiac disease
endogenous levels of IL-27 affected the oncogenic properties of mutant p53 (zeige TP53 Antikörper) in vivo in a Li-Fraumeni mouse model. Lack of IL-27 signaling led to shortened survival times and increased incidence of osteosarcomas.
Interleukin-27 is upregulated centrally and peripherally after intracerebral hemorrhage. Interleukin-27 promotes the tissue-protecting functions of neutrophils via, at least partly, the induction of lactoferrin (zeige LTF Antikörper).
The open reading frame of IL-27 p28 gene is 720 bp, which encodes a protein of 239 amino acids with a predicted molecular mass of 26.6 kDa. The deduced amino acid sequence of IL-27 p28 showed a high degree of homology to human (63%) and mouse (58%).
The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR).
IL-27 p28 subunit
, IL-27 subunit alpha
, interleukin 30
, interleukin-27 subunit alpha
, interluekin 27
, interleukin 27
, interleukin 27 p28 subunit