Interferon Regulatory Factor 2 Binding Protein 2 Proteine (IRF2BP2)

IRF2BP2 encodes an interferon regulatory factor-2 (IRF2) binding protein that interacts with the C-terminal transcriptional repression domain of IRF2. Zusätzlich bieten wir Ihnen IRF2BP2 Antikörper (64) und IRF2BP2 Kits (6) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
IRF2BP2 270110 E9Q1P8
IRF2BP2 359948 Q7Z5L9
Ratte IRF2BP2 IRF2BP2 679357  
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Showing 3 out of 3 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 60 Days
$9,626.73
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 60 Days
$9,626.73
Details
Hefe Zebrafisch His tag   1 mg 60 bis 71 Tage
$3,389.83
Details

IRF2BP2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine)

Human

Weitere Proteine zu Interferon Regulatory Factor 2 Binding Protein 2 (IRF2BP2) Interaktionspartnern

Mouse (Murine) Interferon Regulatory Factor 2 Binding Protein 2 (IRF2BP2) Interaktionspartner

  1. Irf2bp2 gene expression was decreased in CD4 T cells upon activation. Ectopic expression of IRF2BP2 led to a reduction in CD25 expression and STAT5 phosphorylation, along with an impaired proliferative capacity. IRF2BP2 overexpression in differentiated Th cells resulted in reduced IL-4 and pro-TGF-beta production in Th2 and iTregs but had no effect on IFN-gamma or IL-17 expression in Th1 and Th17 cells, respectively.

  2. IRF2BP2 as a novel negative regulator in controlling pathological Cardiac Hypertrophy at the transcriptional level was defined.

  3. Ablation of IRF2BP2 in macrophages worsens atherosclerosis in mice.

  4. IRF2BP2 is a novel ischemia-induced coactivator of VEGFA expression that may contribute to revascularization of ischemic cardiac and skeletal muscles.

Human Interferon Regulatory Factor 2 Binding Protein 2 (IRF2BP2) Interaktionspartner

  1. findings showed that the IRF2BP2-RARalpha fusion has the capacity to transform primary hematopoietic stem/progenitor cells and induced an ATRA-responsive acute promyelocytic leukemia (APL); this provides further evidence that formation of RARA fusion genes represent disease-defining mutations in APL pathogenesis

  2. A novel IRFBP2 mutation was identified in a family with autosomal dominant CVID. Transduction experiments suggest that the mutant protein has an effect on B-cell differentiation and is likely a monogenic cause of the family's CVID phenotype.

  3. ETO2 and IRF2BP2 interacting with the NCOR1/SMRT co-repressor complex, suppresses the expression of erythroid genes until erythroid differentiation.

  4. A deletion variant that lowers IRF2BP2 expression predisposes to coronary artery disease in humans.

  5. analysis of an IRF2BP2-CDX1 fusion gene brought about by translocation t(1;5)(q42;q32) in mesenchymal chondrosarcoma

  6. Nuclear localization of IRF2BP2 depends on phosphorylation near a conserved NLS. Changes in phosphorylation status likely control nucleocytoplasmic localization of IRF2BP2 during muscle differentiation.

  7. results indicate that DIF-1 plays a key role in breast cancer cell survival

  8. Data demonstrate that IRF-2BP2 is a negative regulator of the NFAT1 transcription factor and suggest that NFAT1 repression occurs at the transcriptional level.

  9. IRF2BP2 works with TEAD transcription factors to upregulate the expression of VEGFA in skeletal and cardiac muscle. IRF2BP2 protein levels are increased in response to tissue ischemia.

  10. Identification of IRF-2 binding protein 1 and IRF-2 binding protein 2 as co-repressor molecules for interferon regulatory factor-2.

IRF2BP2 Protein Überblick

Protein Überblick

This gene encodes an interferon regulatory factor-2 (IRF2) binding protein that interacts with the C-terminal transcriptional repression domain of IRF2. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Genbezeichner und Symbole assoziert mit IRF2BP2

  • interferon regulatory factor 2 binding protein 2 (Irf2bp2)
  • interferon regulatory factor 2 binding protein 2 (IRF2BP2)
  • interferon regulatory factor 2 binding protein 2 L homeolog (irf2bp2.L)
  • interferon regulatory factor 2 binding protein 2a (irf2bp2a)
  • interferon regulatory factor 2 binding protein 2b (irf2bp2b)
  • 5n852 Protein
  • E130305N23Rik Protein
  • fj35c12 Protein
  • IRF-2-binding protein 2-B Protein
  • IRF-2BP2 Protein
  • IRF-2BP2-B Protein
  • irf2bp2 Protein
  • irf2bp2-A Protein
  • irf2bp2a Protein
  • irf2bp2b Protein
  • wu:fa12b04 Protein
  • wu:fb73g01 Protein
  • wu:fj35c12 Protein
  • zgc:56251 Protein
  • zgc:63864 Protein

Bezeichner auf Proteinebene für IRF2BP2

IRF-2-binding protein 2 , interferon regulatory factor 2-binding protein 2 , IRF-2BP2 , putative nuclear protein of bilaterial origin (49.6 kD) (5N852) , IRF-2-binding protein 2-A , IRF-2-binding protein 2-B , IRF-2BP2-A , IRF-2BP2-B , interferon regulatory factor 2 binding protein 2 , interferon regulatory factor 2-binding protein 2-A , interferon regulatory factor 2-binding protein 2-B , LOW QUALITY PROTEIN: interferon regulatory factor 2-binding protein 2

GENE ID SPEZIES
270110 Mus musculus
359948 Homo sapiens
380260 Xenopus laevis
335866 Danio rerio
406614 Danio rerio
100716743 Cavia porcellus
679357 Rattus norvegicus
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