G Protein-Coupled Receptor MRGX2 Proteine (MRGPRX2)

seven transmembrane domain G-protein coupled receptor\; most often found in sensory neurons [RGD, Feb 2006].. Zusätzlich bieten wir Ihnen G Protein-Coupled Receptor MRGX2 Antikörper (70) und G Protein-Coupled Receptor MRGX2 Kits (4) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
MRGPRX2 117194 Q96LB1
MRGPRX2 243978 Q3UG50
Ratte MRGPRX2 MRGPRX2 404640  
Direkt bei antikoerper-online bestellen
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Online bestellen
  • orders@antikoerper-online.de

Top G Protein-Coupled Receptor MRGX2 Proteine auf antikoerper-online.de

Showing 4 out of 4 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 50 bis 55 Tage
$7,493.38
Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 50 bis 55 Tage
$5,262.31
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details
Wheat germ Human Unkonjugiert   2 μg Anmelden zum Anzeigen 11 bis 12 Tage
$491.43
Details

MRGPRX2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
,
Mouse (Murine)

Weitere Proteine zu G Protein-Coupled Receptor MRGX2 (MRGPRX2) Interaktionspartnern

Human G Protein-Coupled Receptor MRGX2 (MRGPRX2) Interaktionspartner

  1. Isoliquiritigenin (ISL) dose dependently inhibits C48/80-induced MRGPRX2-expressing HEK293 cell activation. ISL inhibits IgE-independent allergy via the Mrgprx2 pathway.

  2. Study reports that a cysteine protease mucunain, active component of cowhage (itch-inducing spicules or trichomes that cover the seedpods of the tropical plant Mucuna pruriens) that is routinely used in human studies of histamine-independent itch, activates human MRGPRX1 and MRGPRX2 receptors and induces degranulation of human mast cells.

  3. Low levels of MRGPRX2 were detected in non-asthma lung mast cells, but its expression was significantly up-regulated in asthma lung mast cells.

  4. the present study demonstrates that FceRI and MRGPRX2 function can be inversely regulated by SCF in an acute scenario, suggesting that the signaling requirements differ profoundly between the routes.

  5. The authors discuss the possibility that MRGPRX2 responds to various as-yet-unidentified endogenous ligands that have specific characteristics, and propose that MRGPRX2 plays an important role in regulating inflammatory responses to endogenous harmful stimuli, such as protein breakdown products released from damaged or dying cells.

  6. these peptides are identified as fragments of albumin. The isolated fragments activate MRGPRX2 and degranulate MRGPRX2 expressing LAD 2 cells in dose-dependent manner. The isolated basic peptides generated from human albumin are able to degranulate mast cells via the MRGPRX2.

  7. The results showed a kind of mechanism that sinomenine-induced anaphylactoid reactions were mediated by MRGPRX2 via activating PLC molecular signaling pathways to provoke mast cells Ca(2+) mobilization and degranulation.

  8. data suggest that mast cells play important roles in both gingival homeostasis and periodontal disease by orchestrating an interaction between gingival epithelial cells and neutrophils via MRGPRX2-mediated degranulation

  9. MRGX2 is related to nociception, adrenal gland secretion and mast cell degranulation. (Review)

  10. contributes to larger and longer lasting wheal reactions to intradermally injected neuropeptides in patients with chronic urticaria

  11. Ectopic expression of MrgX2 in rat basophilic leukemia RBL-2H3 cells and murine bone marrow mast cells renders these cells responsive to human beta-defensin for degranulation.

  12. identified MrgX2 as a novel G protein-coupled receptor for the antibacterial peptide LL-37 and demonstrated that unlike most G protein-coupled receptors it is resistant to agonist-induced receptor phosphorylation, desensitization, and internalization.

  13. cortistatin-14 shown to be a high affinity ligand for G protein coupled receptor MrgX2 which is expressed in dorsal root ganglion

  14. MRGX2 amino acid substitutions may alter the interactions between MRGX2 protein and its ligand, thus, potentially led to adaptive changes of the pain-perception-related nervous system during human evolution.

  15. Mas, MrgD, and MRG mediated Ang IV-stimulated AA release that was highest for Mas. While Ang III activated Mas and MrgX2, Ang II stimulated AA release via Mas and MRG.

Mouse (Murine) G Protein-Coupled Receptor MRGX2 (MRGPRX2) Interaktionspartner

  1. The results showed a kind of mechanism that sinomenine-induced anaphylactoid reactions were mediated by MRGPRX2 via activating PLC molecular signaling pathways to provoke mast cells Ca(2+) mobilization and degranulation.

G Protein-Coupled Receptor MRGX2 (MRGPRX2) Protein Überblick

Protein Überblick

seven transmembrane domain G-protein coupled receptor\; most often found in sensory neurons

Genbezeichner und Symbole assoziert mit MRGPRX2

  • MAS related GPR family member X2 (MRGPRX2)
  • MAS-related GPR, member X2 (Mrgprx2)
  • MAS related GPR family member X2 (Mrgprx2)
  • G370024M05Rik Protein
  • MrgB1 Protein
  • MrgB10 Protein
  • Mrgprb1 Protein
  • Mrgprb10 Protein
  • MRGX2 Protein

Bezeichner auf Proteinebene für MRGPRX2

G protein-coupled receptor MRGX2 , mas-related G-protein coupled receptor member X2 , MAS-related GPR, member B10 , mas-related G-protein coupled receptor member B10 , MAS-related G protein-coupled receptor, member B1 , MAS-related gene B1

GENE ID SPEZIES
117194 Homo sapiens
243978 Mus musculus
404640 Rattus norvegicus
466465 Pan troglodytes
100434444 Pongo abelii
692078 Macaca mulatta
Ausgewählte Anbieter für G Protein-Coupled Receptor MRGX2 Proteine (MRGPRX2)
Haben Sie etwas anderes gesucht?