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Caveolae are small domains on the inner cell membrane involved in vesicular trafficking and signal transduction. Zusätzlich bieten wir Ihnen Flotillin 1 Kits (12) und Flotillin 1 Proteine (11) und viele weitere Produktgruppen zu diesem Protein an.
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Chicken Monoclonal Flotillin 1 Primary Antibody für IF, WB - ABIN968194
Yamamori, Itakura, Sugaya, Katsumata, Sakagami, Takahashi: Differential expression of SNAP-25 family proteins in the mouse brain. in The Journal of comparative neurology 2011
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Chicken Monoclonal Flotillin 1 Primary Antibody für IF, WB - ABIN968195
Bickel, Scherer, Schnitzer, Oh, Lisanti, Lodish: Flotillin and epidermal surface antigen define a new family of caveolae-associated integral membrane proteins. in The Journal of biological chemistry 1997
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Human Polyclonal Flotillin 1 Primary Antibody für ELISA, IHC - ABIN249540
Vassilieva, Gerner-Smidt, Ivanov, Nusrat: Lipid rafts mediate internalization of beta1-integrin in migrating intestinal epithelial cells. in American journal of physiology. Gastrointestinal and liver physiology 2008
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Human Polyclonal Flotillin 1 Primary Antibody für IHC, IHC (p) - ABIN4312169
Walton, Frey, Vandre, Kwiek, Ishikawa, Takizawa, Robinson, Ackerman: Expression of flotillins in the human placenta: potential implications for placental transcytosis. in Histochemistry and cell biology 2013
Human Polyclonal Flotillin 1 Primary Antibody für IF (p), IHC (p) - ABIN872879
Matsuzaka, Tanihata, Komaki, Ishiyama, Oya, Rüegg, Takeda, Hashido: Characterization and Functional Analysis of Extracellular Vesicles and Muscle-Abundant miRNAs (miR-1, miR-133a, and miR-206) in C2C12 Myocytes and mdx Mice. in PLoS ONE 2016
FLOT1 is associated with aggressive characteristics of HCC (zeige FAM126A Antikörper)
This study presents the endocytic pathways of internalization for muscarinic type 3 receptor and flotillin-1/2 in salivary gland epithelial cells. knockdown of flot-1 or -2 by flotillin (zeige FLOT2 Antikörper)-specific siRNA prevented internalization and reduced the endocytic efficiency of muscarinic type 3 receptor.
Data show that overexpression of 4.1N (zeige EPB41L1 Antikörper) protein decreased expression of flotillin-1, decreased activation of beta-catenin (zeige CTNNB1 Antikörper)/Wnt (zeige WNT2 Antikörper) pathway in non-small-cell lung cancer (NSCLC) cells.
Upregulation of flotillin-1 promotes invasion and metastasis by activating TGF-beta (zeige TGFB1 Antikörper) signaling in nasopharyngeal carcinoma.
Flotillin-1 protein is upregulated in human endometrial cancer and localization shifts from epithelial to stromal with increasing tumor grade
Expression of flotillin-1 was associated with H-Ras (zeige HRAS Antikörper) in breast cancer, especially in TNBC (p < 0.001).
findings revealed the expression of flotillin 1 in gastric cancer samples is significantly higher than that of noncancer/normal tissues; findings suggest that flotillin 1 may be a novel biomarker for gastric cancer
miR (zeige MLXIP Antikörper)-506 expression was down-regulated in clear cell renal cell carcinoma (zeige MOK Antikörper) (ccRCC) and correlated with advanced histologic grade, clinical stage, tumor stage, positive lymph node metastasis, and distant metastasis. FLOT1, a potential target gene of miR (zeige MLXIP Antikörper)-506, was inversely correlated with miR (zeige MLXIP Antikörper)-506 expression in ccRCC tissues.
polycystins are necessary for assembly of a novel flotillin (zeige FLOT2 Antikörper)-containing ciliary signaling complex and provide a molecular rationale for the common renal pathologies caused by OFD1 (zeige OFD1 Antikörper) and polycystin mutations.
Findings suggest that FLOT1 plays an important role in the proliferation and recurrence of transitional cell carcinoma.
an involvement of LRAP (zeige AMELX Antikörper) in lipid-raft-dependent signaling pathways are mediated by flotillin-1.
Downregulation of microRNA-182-5p contributes to renal cell carcinoma (zeige MOK Antikörper) proliferation via activating the AKT (zeige AKT1 Antikörper)/FOXO3a (zeige FOXO3 Antikörper) signaling pathway with FLOT1 being a target.
The role of flotillin 1 and flotillin 2 (zeige FLOT2 Antikörper) in regulating amyloid beta production in a mouse model of cerebral amyloidosis, remains unlear.
elevated levels of Flotillin-1 in hippocampal tissue of mice trained in the Morris water maze confirmed the relevance of Flotillin-1 for memory-related processes in a mammalian system.
a novel signaling network containing FRS2 (zeige FRS2 Antikörper), CAP and flotillin-1
flotillins have a role in NPC1L1 (zeige NPC1L1 Antikörper)-mediated cholesterol uptake and NPC1L1 (zeige NPC1L1 Antikörper)-flotillins-postive cholesterol-enriched membrane microdomains are involved in the mechanism for efficient cholesterol absorption
Data suggest that the association between flotillin 1/2 microdomains and cortical cytoskeleton has important functions during neutrophil migration, in uropod formation, and in the regulation of myosin IIa.
LGI3 (zeige LGI3 Antikörper) interacts with Flo1 in the brain, and LGI3 (zeige LGI3 Antikörper)/Flo1 mediates APP (zeige APP Antikörper) trafficking and exosome formation in neuronal cells: reveals the details of the intracellular transport system and even the secretion pathway in the brain.
Flotillin-1 and caveolin-3 (zeige CAV3 Antikörper) may regulate muscle energy metabolism through the spatial and temporal segregation of key components of the insulin (zeige INS Antikörper) signaling, including GLUT4 (zeige SLC2A4 Antikörper) transport.
Flotillin-1 regulates ephrinB2 (zeige EFNB2 Antikörper) protein levels through ADAM10 (zeige ADAM10 Antikörper), and is required for appropriate neural tube morphogenesis in the Xenopus embryo.
At late tail bud stages, flotillin1A is expressed in branchial arch mesenchyme, the overlying branchial ectoderm and in dorsal somitic mesoderm, whereas flotillin1B expression is more restricted in the dorsal neural tube and head sensory structures.
These results provide the first in vivo evidence that Flotillins regulate E-cadherin (zeige CDH1 Antikörper)-mediated cell-cell junctions to allow epiboly progression.
Analysis of reggie mRNA and protein expression patterns during early zebrafish development revealed that re-1a mRNA is present at high levels in expression domains that overlap with the combined expression pattern of both re-2 (zeige GPR161 Antikörper) genes except at the somites.
Caveolae are small domains on the inner cell membrane involved in vesicular trafficking and signal transduction. FLOT1 encodes a caveolae-associated, integral membrane protein. The function of flotillin 1 has not been determined.
, integral membrane component of caveolae
, flotillin 1c
, flotillin 1a
, flotillin 1