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ENG encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. Zusätzlich bieten wir Ihnen Endoglin Antikörper (777) und Endoglin Proteine (46) und viele weitere Produktgruppen zu diesem Protein an.
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Human ENG ELISA Kit für Sandwich ELISA - ABIN414754
Silva, Teixeira, Oliveira, Almeida, Almeida, Águas, Vasconcelos: Endothelial Dysfunction and Nailfold Videocapillaroscopy Pattern as Predictors of Digital Ulcers in Systemic Sclerosis: a Cohort Study and Review of the Literature. in Clinical reviews in allergy & immunology 2015
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Human ENG ELISA Kit für Sandwich ELISA - ABIN624967
Levy, Finestone: Renal response to four hours of biliary obstruction in the dog. in The American journal of physiology 1983
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Human ENG ELISA Kit für Sandwich ELISA - ABIN2684119
Grisanti, Canbek, Kaiserling, Adam, Lafaut, Gelisken, Szurman, Henke-Fahle, Oficjalska-Mlynczak, Bartz-Schmidt: Expression of endoglin in choroidal neovascularization. in Experimental eye research 2004
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The variant lies in a novel binding-site for the transcription factor Sp1 (zeige SP1 ELISA Kits), known to be involved in the regulation of ENG and ACVRL1 (zeige ACVRL1 ELISA Kits) transcription.
Mobilization of the CD44 (zeige CD44 ELISA Kits)/CD105 positive synovial cells seems to play a role in the genesis of hip osteoarthritis.
Circulating tissue transglutaminase is associated with sFlt-1, soluble endoglin and VEGF in the maternal circulation of preeclampsia patients, suggesting that tTG may have a role in the pathogenesis of PE.
Gestation-adjusted sEng, sFlt-1 and PlGF (zeige PGF ELISA Kits) levels were 11%, 36%, and 30%, respectively, lower in women who later suffered miscarriage compared with unaffected pregnancies
Nuclear survivin (zeige BIRC5 ELISA Kits) expression correlates with endoglin-assessed microvascularisation in laryngeal squamous cell carcinoma.
Dendritic-cells loaded with lysates derived from CD105+ human renal cell carcinoma cancer stem cells (CSCs) induced more functionally specific active T cells and specific antibodies against CSCs, and clearly depressed the tumor growth in mice.
Report no relationship between serum endoglin levels and ovarian cancer microvessel density and tumor endoglin expression.
TGF-beta (zeige TGFB1 ELISA Kits) type I, II, and III receptors were all identified in pregnant serum; all were substantially elevated in early-onset but not late-onset PE. Endoglin was increased in both subtypes.
Study described present a series of pulmonary arterial hypertension patients with mutations in the ENG gene, some of them not previously described, exhibiting clinical and hemodynamic alterations. These results suggest the presence of these mutations may be associated with the severity of the disease.
Several germline variants in Hamartomatous Polyposis Syndrome genes were detected, among them three in ENG, two in BMPR1A (zeige BMPR1A ELISA Kits), one in PTEN, and one in SMAD4 (zeige SMAD4 ELISA Kits). Although some of the detected variants have been reported previously none could be definitely pathogenic or likely pathogenic.
systemic DPP4 (zeige DPP4 ELISA Kits) inhibition restores the impaired mononuclear cell homing in Eng+/- animals post-myocardial infarction, and enhances cardiac repair, which might be explained by restoring the balance between the inflammatory and regenerative macrophages present in the heart
results suggest that soluble endoglin modulates inflammatory-related diseases and open new perspectives leading to the development of novel and targeted approaches for the prevention and treatment of cardiovascular diseases
Endoglin controls blood vessel diameter through endothelial cell shape changes in response to haemodynamic cues.
Endoglin prevents vascular malformation by regulating flow-induced cell migration and specification through VEGFR2 (zeige KDR ELISA Kits) signalling.
Identification of novel regulators of developmental hematopoiesis using Endoglin regulatory elements as molecular probes
Endoglin has an important role in VSMC recruitment and blood vessel maturation during angiogenesis.
the TGFbeta1 (zeige TGFB1 ELISA Kits) coreceptor Eng selectively regulates expression of multiple transient receptor potential channels in the setting of left or right ventricular pressure overload
Endothelial cell-specific endoglin expression in islets of Langerhans is sensitive to VEGF and plays partial roles in driving islet vascular development, however such regulation appears to be distinct to mechanisms required to modulate islet viability and size.
Study provides evidence that the expression of endoglin is required for the establishment of uterine receptivity and the decidualization process, which mediate embryo adhesion or the attachment reaction.
The changes in CD90 (zeige THY1 ELISA Kits) and CD105 expression in the testis and ovary of mice are reported.
This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
endoglin (Osler-Rendu-Weber syndrome 1)
, CD105 antigen
, cell surface MJ7/18 antigen
, transmembrane glycoprotein