anti-Discs, Large Homolog 5 (Drosophila) (DLG5) Antikörper

DLG5 encodes a member of the family of discs large (DLG) homologs, a subset of the membrane-associated guanylate kinase (MAGUK) superfamily.

Alle Antikörper anzeigen	Gen	GeneID	UniProt
Anti-Human DLG5	DLG5	9231	Q8TDM6
Anti-Maus DLG5	DLG5	71228
Anti-Ratte DLG5	DLG5	305645

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Top anti-DLG5 Antikörper auf antikoerper-online.de

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Katalog Nr.	Reaktivität	Wirt	Konjugat	Applikation	Menge	Anbieter	Lieferzeit	Preis	Details
ABIN440510	Human	Kaninchen	Unkonjugiert	IP	100 μL	Anmelden zum Anzeigen	7 bis 9 Tage	$556.31	Details
ABIN440555	Human	Kaninchen	Unkonjugiert	IP, WB	100 μL	Anmelden zum Anzeigen	7 bis 9 Tage	$556.31	Details
ABIN563986	Human	Maus	Unkonjugiert	ELISA, WB	100 μg	Anmelden zum Anzeigen	11 bis 12 Tage	$440.00	Details
ABIN563985	Human	Maus	Unkonjugiert	ELISA, WB	50 μL	Anmelden zum Anzeigen	11 bis 12 Tage	$305.71	Details
ABIN2598598	Human	Maus	Unkonjugiert	ELISA, WB	100 μg	Anmelden zum Anzeigen	7 bis 9 Tage	$837.83	Details
ABIN1978476	Meerschweinchen	Kaninchen	Unkonjugiert	IP	100 μL	Anmelden zum Anzeigen	7 bis 9 Tage	$595.83	Details
ABIN1978475	Rind (Kuh)	Kaninchen	Unkonjugiert	IP, WB	100 μL	Anmelden zum Anzeigen	7 bis 9 Tage	$595.83	Details
ABIN5076288	Human	Kaninchen	Unkonjugiert	ICC, IF	100 μL	Anmelden zum Anzeigen	10 bis 13 Tage	$491.63	Details
ABIN5013462	Human	Kaninchen	Unkonjugiert	ICC, IHC, WB	100 μg	Anmelden zum Anzeigen	15 bis 18 Tage	$350.00	Details
ABIN5013461	Maus	Kaninchen	Unkonjugiert	ICC, IHC, WB	100 μg	Anmelden zum Anzeigen	15 bis 18 Tage	$360.00	Details

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Weitere Antikörper gegen DLG5 Interaktionspartner

Human Discs, Large Homolog 5 (Drosophila) (DLG5) Interaktionspartner

both polymorphisms of DLG5 are correlated with inflammatory bowel disease susceptibility in an ethnic-specific manner.
Low expression of DLG5 is associated with Crohn's disease.
Data found that Dlg5 expression was significantly lower in human hepatocellular carcinoma (HCC (zeige FAM126A Antikörper)) tissues and indicate that Dlg5 acts as a novel regulator of invadopodium-associated invasion via Girdin (zeige CCDC88A Antikörper) and by interfering with the interaction between Girdin (zeige CCDC88A Antikörper) and Tks5 (zeige SH3PXD2A Antikörper), which might be important for Tks5 (zeige SH3PXD2A Antikörper) phosphorylation in HCC (zeige FAM126A Antikörper) cells.
DLG5 inhibits the association between MST1 (zeige MST1 Antikörper)/2 and large tumor suppressor (zeige LATS1 Antikörper) homologs 1/2 (LATS1 (zeige LATS1 Antikörper)/2), uses its scaffolding function to link MST1 (zeige MST1 Antikörper)/2 with MARK3 (zeige MARK3 Antikörper), and inhibits MST1 (zeige MST1 Antikörper)/2 kinase activity
study has identified several new proteins like RHOC (zeige RHOC Antikörper), DLG5, UGDH (zeige UGDH Antikörper), TMOD3 (zeige TMOD3 Antikörper) in addition to known chemoresistance associated proteins in non-small cell lung carcinoma.
These data suggest that inhibition of Dlg5 by DNA hypermethylation contributes to provoke invasive phenotypes in bladder tumor.
Findings demonstrate that Dlg5 interacts with and inhibits the activity of Girdin (zeige CCDC88A Antikörper), thereby suppressing the migration of prostate cancer cells.
DLG5 plays a role in cell migration, cell adhesion, precursor cell division, cell proliferation, epithelial cell polarity maintenance, and transmission of extracellular signals to the membrane and cytoskeleton.
Overexpression of Dlg5 enhances the degradation of TGFBRI.
Polymorphisms in the DLG5 gene were found to be associated with Crohn's disease patients in Malaysia.

Mouse (Murine) Discs, Large Homolog 5 (Drosophila) (DLG5) Interaktionspartner

Dlg5 is required for Hh-induced enrichment of Kif7 (zeige KIF7 Antikörper) and Gli2 (zeige GLI2 Antikörper) at the tip of the cilium but is dispensable for Gpr161 (zeige GPR161 Antikörper) exit from the cilium and the consequent suppression of Gli3 (zeige GLI3 Antikörper) processing into its repressor form
DLG5 is a MAGUK protein that regulates spine formation, synaptogenesis, and synaptic transmission in cortical neurons.
Dlg5 maintains apical aPKC and regulates progenitor differentiation during lung morphogenesis.
Data report that Discs large (zeige DLG4 Antikörper) 5 (Dlg5), a member of the MAGUK family, is an interactor of CitK required for CitK polarization.

DLG5 Antigen-Profil

Protein Überblick

This gene encodes a member of the family of discs large (DLG) homologs, a subset of the membrane-associated guanylate kinase (MAGUK) superfamily. The MAGUK proteins are composed of a catalytically inactive guanylate kinase domain, in addition to PDZ and SH3 domains, and are thought to function as scaffolding molecules at sites of cell-cell contact. The protein encoded by this gene localizes to the plasma membrane and cytoplasm, and interacts with components of adherens junctions and the cytoskeleton. It is proposed to function in the transmission of extracellular signals to the cytoskeleton and in the maintenance of epithelial cell structure. Alternative splice variants have been described but their biological nature has not been determined.

Genbezeichner und Symbole assoziert mit DLG5

discs large MAGUK scaffold protein 5 (DLG5) Antikörper
discs, large homolog 5 (Drosophila) (DLG5) Antikörper
discs, large homolog 5a (Drosophila) (dlg5a) Antikörper
discs, large homolog 5 (Drosophila) (Dlg5) Antikörper
discs large MAGUK scaffold protein 5 (Dlg5) Antikörper

4933429D20Rik Antikörper
dlg5 Antikörper
LP-DLG Antikörper
mKIAA0583 Antikörper
P-DLG5 Antikörper
PDLG Antikörper
T25557 Antikörper
wu:fc28f03 Antikörper

Bezeichner auf Proteinebene für DLG5

discs, large homolog 5 (Drosophila) , discs large homolog 5 , discs large protein , discs, large homolog 5 , disks large homolog 5 , discs large protein LP-DLG , discs large protein P-dlg , large type of P-DLG , placenta and prostate DLG

GENE ID	SPEZIES
703123	Macaca mulatta
423728	Gallus gallus
535699	Bos taurus
489061	Canis lupus familiaris
448848	Sus scrofa
569065	Danio rerio
100225167	Taeniopygia guttata
9231	Homo sapiens
71228	Mus musculus
305645	Rattus norvegicus

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