anti-Discs, Large (Drosophila) Homolog-Associated Protein 1 (DLGAP1) Antikörper

Part of the postsynaptic scaffold in neuronal cells.. Zusätzlich bieten wir Ihnen DLGAP1 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
DLGAP1 9229 O14490
DLGAP1 224997 Q9D415
DLGAP1 65040 P97836
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Top anti-DLGAP1 Antikörper auf antikoerper-online.de

Showing 10 out of 70 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Huhn Kaninchen Unkonjugiert WB Western blot analysis of GKAP expression in MDAMB231 (A), HEK293T (B) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Maus Unkonjugiert ELISA, ICC, IHC, WB Red: Control Antigen (100ng);Purple: Antigen (10ng);Green: Antigen (50ng);Blue: Antigen (100ng); Dilution: 1/10000 Figure 1: Western blot analysis using GKAP mAb against HEK293 (1) and GKAP(AA: 490-663)-hIgGFc transfected HEK293 (2) cell lysate. Dilution: 1/500 - 1/2000 100 μL Anmelden zum Anzeigen 8 bis 11 Tage
$577.50
Details
Fledermaus Ziege Unkonjugiert IHC, IHC (p) Brain, cortex, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-DLGAP1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml. 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$484.00
Details
Human Kaninchen Unkonjugiert ELISA, IF, IHC, WB 100 μL Anmelden zum Anzeigen Verfügbar
$363.46
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Human Kaninchen Unkonjugiert IF, ELISA, WB 100 μL Anmelden zum Anzeigen 11 bis 14 Tage
$493.17
Details
Human Kaninchen Unkonjugiert FACS, WB Western blot analysis of DLGAP1 Antibody (N-term) (ABIN390832) in MDA-MB231 cell line lysates (35 µg/lane). DLGAP1 (arrow) was detected using the purified polyclonal antibody. Flow cytometric analysis of MDA-231 cells using DLGAP1 Antibody (N-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$385.00
Details
Human Kaninchen Unkonjugiert IHC, WB ABIN6267120 at 1/100 staining Human thyroid cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. Western blot analysis of extracts of rat brain tissue, using Phospho-GKAP (Ser346) Antibody. 100 μL Anmelden zum Anzeigen 11 bis 12 Tage
$390.77
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of Phospho-GKAP (Ser25) in lysates of Mouse brain, using Phospho-GKAP (Ser25) Antibody(ABIN6268165). 100 μL Anmelden zum Anzeigen 11 bis 12 Tage
$450.00
Details
Human Kaninchen Unkonjugiert EIA, WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$484.00
Details
Human Maus Unkonjugiert ELISA, IF, IHC, IHC (p), WB 100 μL Anmelden zum Anzeigen 11 bis 14 Tage
$551.83
Details

Am meisten referenzierte anti-DLGAP1 Antikörper

  1. Human Polyclonal DLGAP1 Primary Antibody für IHC, ELISA - ABIN1003103 : Takeuchi, Hata, Hirao, Toyoda, Irie, Takai: SAPAPs. A family of PSD-95/SAP90-associated proteins localized at postsynaptic density. in The Journal of biological chemistry 1997 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal DLGAP1 Primary Antibody für IHC (p), WB - ABIN541356 : Kindler, Rehbein, Classen, Richter, Böckers: Distinct spatiotemporal expression of SAPAP transcripts in the developing rat brain: a novel dendritically localized mRNA. in Brain research. Molecular brain research 2004 (PubMed)
    Show all 3 Pubmed References

  3. Mammalian Monoclonal DLGAP1 Primary Antibody für ISt, IHC - ABIN1304945 : Bangash, Park, Melnikova, Wang, Jeon, Lee, Syeda, Kim, Kouser, Schwartz, Cui, Zhao, Speed, Kee, Tu, Hu, Petralia, Linden, Powell, Savonenko, Xiao, Worley: Enhanced polyubiquitination of Shank3 and NMDA receptor in a mouse model of autism. in Cell 2011 (PubMed)
    Show all 2 Pubmed References

  4. Human Monoclonal DLGAP1 Primary Antibody für ICC, IHC - ABIN969175 : Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ... in American journal of human genetics 2009 (PubMed)
    Show all 2 Pubmed References

  5. Human Monoclonal DLGAP1 Primary Antibody für IHC, ELISA - ABIN966203 : Davila, Froeling, Tan, Bonnard, Boland, Snippe, Hibberd, Seielstad: New genetic associations detected in a host response study to hepatitis B vaccine. in Genes and immunity 2010 (PubMed)
    Show all 2 Pubmed References

  6. Rat (Rattus) Monoclonal DLGAP1 Primary Antibody für ICC, IF - ABIN5682677 : Grabrucker, Jannetti, Eckert, Gaub, Chhabra, Pfaender, Mangus, Reddy, Rankovic, Schmeisser, Kreutz, Ehret, Boeckers, Grabrucker: Zinc deficiency dysregulates the synaptic ProSAP/Shank scaffold and might contribute to autism spectrum disorders. in Brain : a journal of neurology 2014 (PubMed)

Weitere Antikörper gegen DLGAP1 Interaktionspartner

Human Discs, Large (Drosophila) Homolog-Associated Protein 1 (DLGAP1) Interaktionspartner

  1. Study presents evidence that the expression of GKAP modulates the activity of the glutamate-to-NMDAR signaling pathway and promotes invasiveness in mouse neuroendocrine (PanNET) and in both mouse and human ductal (PDAC) cancer cell lines.

  2. Association of two significant SNPs of DLGAP1 with cognitive flexibility in Attention Deficit Hyperactivity Disorder was observed.

  3. This study revealed a significant variant (rs12455524) within the gene DLGAP1 for Recurrent major depression.

  4. These results strongly suggested involvement of the DLGAP1 gene product in the development of HIV-related lipoatrophy in Thai HIV patients.

  5. This study showed that DLGAP1 association with obsessive-compulsive disorder.

  6. Dimerization of DLC2 was required for its interaction with GKAP, which, in turn, potentiated GKAP self-association.

  7. Results show that the expression and distribution of NMDA receptors subunits GluN1, GluN2A and GluN2B - together with that of postsynaptic protein PSD-95 - are modified in Alzheimer's disease compared to normal aging

  8. dlgap1 showed the highest association, of snps examined, with ocd.

  9. Study identified six genetic variants, (rs145691437, rs3786431, rs201567254, rs3745051 and rs11662259) and one rare missense mutation (c.1922A>G). SNP- and haplotype-based analyses showed no association of these SNPs with schizophrenia.

  10. The GKAP controls the forces operating on microtubules and play a fundamental role in centrosome positioning and cell polarity.

Mouse (Murine) Discs, Large (Drosophila) Homolog-Associated Protein 1 (DLGAP1) Interaktionspartner

  1. These data suggest that Dlgap1 knockout leads to post-synaptic density disruption and reduced sociability, consistent with reports of DLGAP1 haploinsufficient variants in schizophrenia and autism spectrum disorder.

  2. GKAP-DLC2 interaction organizes the postsynaptic scaffold complex to enhance synaptic NMDA receptor activity.

  3. Expression of Dlgap1 in the mouse prefrontal cortex is modulated by a sequence variant (B2 SINE indel) in the 3' UTR of Comt (catechol-O-methyltransferase).

  4. the loss of the SH3, protein 4.1 and/or GUK domains of Dlg1 disrupt epithelial polarity and perturb nephrogenesis either as a secondary consequence to a defect in ureteric branching morphogenesis and/or delay in mesenchyme-to- epithelial transition

  5. results suggest that inactivation of Dlg1 augments HTLV-1 Tax-mediated transformation of the T-cell line (CTLL-2)

  6. Semi-quantitative analysis of RNA levels in FMRP immunoprecipitates showed that in the mouse brain mRNAs encoding PSD components, such as Shank1, SAPAP1-3, PSD-95, and the glutamate receptor subunits NR1 and NR2B, are associated with FMRP.

DLGAP1 Antigen-Profil

Protein Überblick

Part of the postsynaptic scaffold in neuronal cells.

Genbezeichner und Symbole assoziert mit DLGAP1

  • DLG associated protein 1 (DLGAP1) Antikörper
  • discs, large (Drosophila) homolog-associated protein 1 (DLGAP1) Antikörper
  • disks large-associated protein 1 (LOC100408093) Antikörper
  • disks large-associated protein 1 (LOC100548434) Antikörper
  • DLG associated protein 1 (dlgap1) Antikörper
  • discs, large homolog-associated protein 1 (dlgap1) Antikörper
  • discs, large (Drosophila) homolog-associated protein 1 (Dlgap1) Antikörper
  • DLG associated protein 1 (Dlgap1) Antikörper
  • discs, large (Drosophila) homolog-associated protein 1b (dlgap1b) Antikörper
  • 4933422O14Rik Antikörper
  • 9630002F18 Antikörper
  • AI845682 Antikörper
  • AI848168 Antikörper
  • BB075781 Antikörper
  • D17Bwg0511e Antikörper
  • DAP-1 Antikörper
  • DAP-1-ALPHA Antikörper
  • DAP-1-BETA Antikörper
  • DKFZp469D0713 Antikörper
  • Gkap Antikörper
  • GKAP/SAPAP Antikörper
  • GKPA/SAPAP Antikörper
  • hGKAP Antikörper
  • mKIAA4162 Antikörper
  • Sapap1 Antikörper

Bezeichner auf Proteinebene für DLGAP1

discs, large (Drosophila) homolog-associated protein 1 , discs large homolog-associated protein 1 , discs, large homolog-associated protein 1 , disks large-associated protein 1 , disks large-associated protein 1-like , PSD-95/SAP90 binding protein 1 , SAP90/PSD-95-associated protein 1 , guanylate kinase-associated protein , DAP-1 beta , PSD-95/SAP90-binding protein 1 , SAP90/PSD-95 associated protein 1 , guanylate kinase associated protein , DAP-1 , SAPAP1 , rGKAP

GENE ID SPEZIES
428520 Gallus gallus
455311 Pan troglodytes
480194 Canis lupus familiaris
526435 Bos taurus
100012355 Monodelphis domestica
100174543 Pongo abelii
100342375 Oryctolagus cuniculus
100408093 Callithrix jacchus
100548434 Meleagris gallopavo
100564980 Anolis carolinensis
100591069 Nomascus leucogenys
100626809 Sus scrofa
100170582 Xenopus (Silurana) tropicalis
9229 Homo sapiens
224997 Mus musculus
65040 Rattus norvegicus
571372 Danio rerio
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