anti-Deleted in Azoospermia-Like (DAZL) Antikörper

The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. Zusätzlich bieten wir Ihnen DAZL Proteine (11) und DAZL Kits (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
DAZL 1618 Q92904
DAZL 680486  
DAZL 13164 Q64368
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Top anti-DAZL Antikörper auf antikoerper-online.de

Showing 10 out of 83 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-DAZL Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:12500<br><b>Positive Control: </b>721_B cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Ziege Unkonjugiert IHC, ELISA, WB ABIN185441 (0.1µg/ml) staining of human ovary lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Human Ziege Unkonjugiert IHC (p), IHC, ELISA, WB ABIN250853 (0.1ug/ml) staining of Human Ovary lysate (35ug protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Immunohistochemistry-Paraffin: DAZL Antibody [ABIN250853] - Stainingof paraffin embedded Mouse Testis. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$485.88
Details
Rind (Kuh) Ziege Unkonjugiert EIA, IHC (p), WB   0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
$455.40
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: DAZL Antibody [NBP1-85306] - Staining of human cell line A-431 shows positivity in cytoplasm. Western Blot: DAZL Antibody [NBP1-85306] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Negative control (vector only transfected HEK293T lysate).Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY400541) 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details
Human Kaninchen Unkonjugiert WB WB Image DAZL antibody detects DAZL protein by western blot analysis. Whole cell extracts (30 μg) and Mouse tissue extracts (50 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with DAZL antibody , diluted at a dilution of 1:1000. 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
$358.60
Details
Human Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Rind (Kuh) Ziege Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$610.50
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of extracts of SW480 cells, using DAZL antibody. 100 μL Anmelden zum Anzeigen 16 Days
$476.15
Details

DAZL Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-DAZL Antikörper

  1. Human Polyclonal DAZL Primary Antibody für IHC (p), IHC - ABIN250853 : Hermann, Sukhwani, Lin, Sheng, Tomko, Rodriguez, Shuttleworth, McFarland, Hobbs, Pandolfi, Schatten, Orwig: Characterization, cryopreservation, and ablation of spermatogonial stem cells in adult rhesus macaques. in Stem cells (Dayton, Ohio) 2007 (PubMed)
    Show all 7 Pubmed References

  2. Cynomolgus Monoclonal DAZL Primary Antibody für IF, IHC (p) - ABIN2473235 : Fabre, Bureau, Pouliquen, Lorans: Binding sites for human interleukin 1 alpha, gamma interferon and tumor necrosis factor on cultured fibroblasts of normal cornea and keratoconus. in Current eye research 1991 (PubMed)
    Show all 4 Pubmed References

  3. Human Polyclonal DAZL Primary Antibody für IF (p), IHC (p) - ABIN1385600 : Zhang, Zhao, Zhang, Hao, Yu, Min, Li, Ma, Chen, Yi, Tang, Meng, Liu, Wang, Shen, Zhang: Decrease in male mouse fertility by hydrogen sulfide and/or ammonia can Be inheritable. in Chemosphere 2018 (PubMed)

  4. Human Polyclonal DAZL Primary Antibody für ICC, IF - ABIN4304346 : Djureinovic, Fagerberg, Hallström, Danielsson, Lindskog, Uhlén, Pontén: The human testis-specific proteome defined by transcriptomics and antibody-based profiling. in Molecular human reproduction 2014 (PubMed)

Weitere Antikörper gegen DAZL Interaktionspartner

Human Deleted in Azoospermia-Like (DAZL) Interaktionspartner

  1. computational analysis of free energy change due to this point mutation using GROMOS96 indicated decreased stability of the DAZL protein. The N109T variant in an infertile male population may provide a genetic marker for mutational analysis of DAZL

  2. Data suggest that DAZL may be one such factor in human female fertility

  3. Through the translational regulation of novel RNA targets SMC1B (zeige SMC1B Antikörper) and TEX11 (zeige TEX11 Antikörper), DAZL may have a key role in regulating chromosome cohesion and DNA recombination; two processes fundamental in determining oocyte quality and whose establishment in foetal life may support lifelong fertility.

  4. hypermethylation of DAZL and BOULE (zeige BOLL Antikörper) promoters in human sperm is associated with human infertility

  5. data can be used to further elucidate the role of NANOS3 (zeige NANOS3 Antikörper) and DAZL in germ cell development both in vitro and in vivo

  6. DAZL was not expressed either in normal cultures or lesions from cervixes with papillomavirus infections and cervical intraepithelial neoplasia.

  7. analysis demonstrated that SNP260 of DAZL did not contribute to oligo/azoospermia while SNP386 was correlated to male infertility

  8. Neither the A260G nor the A386G polymorphism of DAZL appeared to be involved in male infertility.

  9. demonstrate that Boll (zeige BOLL Antikörper) is also transiently expressed during oogenesis in the fetal mouse ovary, but is simultaneously co-expressed within the same germ cells as Dazl

  10. Abnormal DNA methylation (zeige HELLS Antikörper) of the DAZL promoter might represent an epigenetic marker of male infertility.

Zebrafish Deleted in Azoospermia-Like (DAZL) Interaktionspartner

  1. Cortical depth and differential transport of vegetally localized dorsal and germ line determinants, Wnt8a (zeige WNT8A Antikörper), grip2a, and Dazl, in the zebrafish embryo have been presented.

  2. that DAZL specifically binds the HuB 3'UTR (zeige UTS2R Antikörper) and protects the message from degradation and/or enhances HuB translation, leading to the germ cell specific expression of HuB protein.

  3. DAZL relieves miRNA-mediated repression of germline mRNAs by controlling poly(A) tail length in zebrafish

  4. Data show that DAZ-like protein directly promotes the translation of the target mRNAs in vertebrates.

Cow (Bovine) Deleted in Azoospermia-Like (DAZL) Interaktionspartner

  1. analysis of genomic structure and transcript variants of the bovine DAZL gene

Xenopus laevis Deleted in Azoospermia-Like (DAZL) Interaktionspartner

  1. The dynamic intracellular localization suggests that Dazl is a multifunctional protein regulating RNA metabolism required for Xenopus germline development

  2. Daz- and pumilio-like genes are asymmetrically localized in Pelophylax (Rana) oocytes and are expressed during early spermatogenesis.

  3. Dazl has the ability to stimulate translation and function at the level of translation initiation.

Mouse (Murine) Deleted in Azoospermia-Like (DAZL) Interaktionspartner

  1. Down-regulated expression of Sox9 (zeige SOX9 Antikörper) and Dazl may play important roles in MBP (zeige MBP Antikörper)-induced testis injury.

  2. DAZL and CPEB1 (zeige CPEB1 Antikörper) regulate mRNA translation during oocyte maturation.

  3. findings demonstrate that DAZL associates with mRNA of Tet1 (zeige TET1 Antikörper), a catalyst of 5-hydroxylation of methyl-cytosine, and enhances Tet1 (zeige TET1 Antikörper) mRNA translation; DAZL enhances TET1 (zeige TET1 Antikörper)-mediated cytosine hydroxymethylation in embryonic stem cells that are actively reprogramming to a pluripotent ground state

  4. Both yeast and mouse contain an RNA-binding protein, Rim4 (zeige RIMS4 Antikörper) and DAZL, respectively, that functions in translation and forms SDS (zeige SDS Antikörper)-resistant aggregates during gametogenesis.

  5. Our findings strengthen the importance of RA and Dazl in the meiotic transition, provide important details about the Stra8 (zeige STRA8 Antikörper) pathway, and open avenues to investigate early meiosis through analysis of Rec8 (zeige REC8 Antikörper) induction and function

  6. Data indicate that the germ cell-specific RNA binding protein DAZL limits both pluripotency and somatic differentiation in nascent primordial germ cells (PGCs).

  7. demonstrate that Boll (zeige BOLL Antikörper) is also transiently expressed during oogenesis in the fetal mouse ovary, but is simultaneously co-expressed within the same germ cells as Dazl

  8. Studies indicate that in Dazl-Knockout mice, cord/tubule-like structures, OSE invaginations and clusters of steroidogenic cells became increasingly prominent with age, but these abnormal structures remained benign.

  9. alternative splicing of exon8 of mDazl leads to the generation of the novel splice variant, Dazl-Delta8.

  10. DAZL was translocated to stress granules upon heat stress. Furthermore, stress granule assembly was significantly diminished in the early male germ cells of Dazl-knockout mice. DAZL induced the sequestration of signaling molecules such as RACK (zeige GNB2L1 Antikörper).

Pig (Porcine) Deleted in Azoospermia-Like (DAZL) Interaktionspartner

  1. cloning & characterization of the Deleted in AZoospermia Like (pDAZL) gene; pDAZL gene might be a good candidate gene of litter size trait & provides some marker information for marker-assisted selection.

  2. DNA methylation (zeige HELLS Antikörper) may suppress DAZL expression in somatic cells by interfering with Sp1 (zeige SP1 Antikörper) binding.

  3. The porcine DAZL coding sequence is highly homologous to those reported for the human and mouse cDNAs, and DAZL expression increases during oocyte maturation.

  4. MK is able to maintain a proliferative PGC (zeige PGC Antikörper) phenotype mediated by the suppression of DAZL in early germ cells

  5. DAZL enhances in vitro derived porcine germ cell formation and meiosis.

  6. DAZL c.570+385 A>G and DAZL c.735+150 C>A locus were the potential molecular markers for improving the sperm quality traits in pigs.

DAZL Antigen-Profil

Protein Überblick

The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. Two transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit DAZL

  • deleted in azoospermia like (DAZL) Antikörper
  • deleted in azoospermia-like (DAZL) Antikörper
  • deleted in azoospermia-like (dazl) Antikörper
  • deleted in azoospermia-like (Dazl) Antikörper
  • deleted in azoospermia-like L homeolog (dazl.L) Antikörper
  • deleted in azoospermia like (dazl) Antikörper
  • deleted in azoospermia like (Dazl) Antikörper
  • Daz-like Antikörper
  • Dazh Antikörper
  • DAZL Antikörper
  • dazl-a Antikörper
  • dazl-B Antikörper
  • Dazl1 Antikörper
  • Dazla Antikörper
  • spgyla Antikörper
  • Tpx-2 Antikörper
  • Tpx2 Antikörper
  • Xdazl Antikörper

Bezeichner auf Proteinebene für DAZL

DAZ homolog , DAZ-like autosomal , SPGY-like-autosomal , deleted in azoospermia-like 1 , germline specific RNA binding protein , spermatogenesis gene on the Y-like autosomal , deleted in azoospermia-like , DAZ-like protein , deleted in azoospermia-like protein , deleted in azoospermia protein 3 , xtdazl , DAZ-like protein A , DAZ-like protein B , Deleted in azoospermia-like-B , deleted in azoospermia-like-A , xDazl-A , xDazl-B , Deleted in azoospermia-like 1

GENE ID SPEZIES
1618 Homo sapiens
460209 Pan troglodytes
695763 Macaca mulatta
58039 Danio rerio
477055 Canis lupus familiaris
530116 Bos taurus
680486 Rattus norvegicus
394676 Xenopus (Silurana) tropicalis
374054 Gallus gallus
398041 Xenopus laevis
13164 Mus musculus
100410648 Callithrix jacchus
100453294 Pongo abelii
100484743 Ailuropoda melanoleuca
100542379 Meleagris gallopavo
100556590 Anolis carolinensis
100579498 Nomascus leucogenys
100625706 Sus scrofa
100722319 Cavia porcellus
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