anti-Dedicator of Cytokinesis 4 (DOCK4) Antikörper

DOCK4 is a member of the dedicator of cytokinesis (DOCK) family and encodes a protein with a DHR-1 (CZH-1) domain, a DHR-2 (CZH-2) domain and an SH3 domain. Zusätzlich bieten wir Ihnen DOCK4 Kits (6) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
DOCK4 238130 P59764
DOCK4 9732 Q8N1I0
DOCK4    
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Top anti-DOCK4 Antikörper auf antikoerper-online.de

Showing 10 out of 37 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Human Maus Unkonjugiert IF, ELISA, WB 100 μg 11 bis 14 Tage
$551.83
Details
Human Maus Unkonjugiert IF, IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to DOCK4 on formalin-fixed paraffin-embedded human breast cancer. [antibody concentration 3 ug/ml] DOCK4 monoclonal antibody (M01), clone 3E7 Western Blot analysis of DOCK4 expression in Hela NE 100 μg 11 bis 12 Tage
$440.00
Details
Human Kaninchen Unkonjugiert ICC, IHC, WB Western Blot; Sample: Human Hela cell lysate; ;Primary Ab: 1µg/ml Rabbit Anti-Human DOCK4 Antibody;Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody;(Catalog: SAA544Rb19) Figure. Western Blot; Sample: Recombinant protein. 100 μg 13 bis 16 Tage
$350.00
Details
Human Maus Unkonjugiert ELISA, WB DOCK4 monoclonal antibody (M01A), clone 3E7 Western Blot analysis of DOCK4 expression in Hela NE DOCK4 monoclonal antibody (M01A), clone 3E7. Western Blot analysis of DOCK4 expression in HeLa. 200 μL 11 bis 12 Tage
$440.00
Details
Human Maus Unkonjugiert ELISA, WB Western Blot detection against Immunogen (37.11 KDa) . 50 μL 11 bis 12 Tage
$305.71
Details
Human Kaninchen Cy7 IF (p)   100 μL 14 bis 21 Tage
$416.90
Details
Human Kaninchen HRP IHC (p), WB   100 μL 14 bis 21 Tage
$416.90
Details
Human Kaninchen Cy5.5 IF (p)   100 μL 14 bis 21 Tage
$416.90
Details
Human Kaninchen Alexa Fluor 555 IF (p)   100 μL 14 bis 21 Tage
$416.90
Details
Human Kaninchen Alexa Fluor 488 IF (p)   100 μL 14 bis 21 Tage
$416.90
Details

Am meisten referenzierte anti-DOCK4 Antikörper

  1. Human Monoclonal DOCK4 Primary Antibody für IF, IHC (p) - ABIN564203 : Eiring, Neviani, Santhanam, Oaks, Chang, Notari, Willis, Gambacorti-Passerini, Volinia, Marcucci, Caligiuri, Leone, Perrotti: Identification of novel posttranscriptional targets of the BCR/ABL oncoprotein by ribonomics: requirement of E2F3 for BCR/ABL leukemogenesis. in Blood 2008 (PubMed)

Weitere Antikörper gegen DOCK4 Interaktionspartner

Mouse (Murine) Dedicator of Cytokinesis 4 (DOCK4) Interaktionspartner

  1. Dock4 binds to SH3YL1 through the C-terminal proline-rich region.

  2. The Atypical guanine nucleotide exchange factor Dock4 regulates neurite differentiation through modulation of Rac1 GTPase and actin dynamics.

  3. Rac-DOCK4-actin-binding protein harmonin-activated signaling pathway is possibly involved in regulating actin cytoskeleton organization in stereocilia of the inner ear.

Human Dedicator of Cytokinesis 4 (DOCK4) Interaktionspartner

  1. DOCK4 over expression suppresses selfrenewal and tumorigenicity of glioblastoma (GBM) stem-like cells. Accordingly in the frame of GBM median of survival, increased level of DOCK4 predicts improved patient survival.

  2. DOCK4 signalling is necessary for lateral filopodial protrusions and tubule remodelling prior to vascular lumen formation

  3. These data identify DOCK4 as a putative 7q gene whose reduced expression can lead to erythroid dysplasia

  4. activator DOCK4 as a key component of the TGF-beta/Smad pathway that promotes lung ADC cell extravasation and metastasis.

  5. The study found significant associations between autism and a SNP of the DOCK4 gene.

  6. The Atypical guanine nucleotide exchange factor Dock4 regulates neurite differentiation through modulation of Rac1 GTPase and actin dynamics.

  7. This study revealed ROCK4 as novel schizophrenia candidate genes in the Jewish population.

  8. novel epigenetic alterations in myelodysplastic leukocytes and implicate DOCK4 as a pathogenic gene located on the 7q chromosomal region.

  9. Evidence for the involvement of DOCK4 in autism susceptibility was supported by independent replication of association at rs2217262 and the finding of a deletion segregating in a sib-pair family

  10. Data suggest that exonic deletions of DOCK4 may act as a risk factor for reading impairment. Genomic disruption of both DOCK4 and CNTNAP5 genes may have an additive effect and may result in a more severe autism spectrum phenotype.

  11. Taken together, these results suggest that Dock4 plays an important role in the regulation of cell migration through activation of Rac1, and that RhoG is a key upstream regulator for Dock4.

  12. DOCK4 may be regulated by PIP(3) to exert its function

  13. DOCK4 interacts with the beta-catenin degradation complex, consisting of the proteins adenomatosis polyposis coli, Axin and glycogen synthase kinase 3beta.

  14. Cell migration is regulated by platelet-derived growth factor receptor endocytosis, which involves DOCK4.

DOCK4 Antigen-Profil

Protein Überblick

This gene is a member of the dedicator of cytokinesis (DOCK) family and encodes a protein with a DHR-1 (CZH-1) domain, a DHR-2 (CZH-2) domain and an SH3 domain. This membrane-associated, cytoplasmic protein functions as a guanine nucleotide exchange factor and is involved in regulation of adherens junctions between cells. Mutations in this gene have been associated with ovarian, prostate, glioma, and colorectal cancers. Alternatively spliced variants which encode different protein isoforms have been described, but only one has been fully characterized.

Genbezeichner und Symbole assoziert mit DOCK4

  • dedicator of cytokinesis 4 (DOCK4) Antikörper
  • dedicator of cytokinesis 4 (NAEGRDRAFT_81257) Antikörper
  • dedicator of cytokinesis 4 (Dock4) Antikörper
  • 5330406C03 Antikörper
  • 6330411N01Rik Antikörper
  • AF263288 Antikörper
  • C030023J22 Antikörper
  • DOCK4 Antikörper
  • mKIAA0716 Antikörper

Bezeichner auf Proteinebene für DOCK4

dedicator of cytokinesis 4 , dedicator of cytokinesis protein 4-like , dedicator of cytokinesis protein 4

GENE ID SPEZIES
463661 Pan troglodytes
703726 Macaca mulatta
8858503 Naegleria gruberi strain NEG-M
100055674 Equus caballus
100355539 Oryctolagus cuniculus
100406117 Callithrix jacchus
100464976 Ailuropoda melanoleuca
100547814 Meleagris gallopavo
100604748 Nomascus leucogenys
238130 Mus musculus
9732 Homo sapiens
417779 Gallus gallus
482407 Canis lupus familiaris
100520706 Sus scrofa
534227 Bos taurus
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